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Blood vessel networks in the brain play a crucial role in stroke research, where understanding their topology is essential for analyzing blood flow dynamics. However, extracting detailed topological vessel network information from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Joël Mathys , Andreas Plesner , Jorel Elmiger , Roger Wattenhofer

Single-cell RNA sequencing (scRNA-seq) has the potential to provide powerful, high-resolution signatures to inform disease prognosis and precision medicine. This paper takes an important first step towards this goal by developing an…

Quantitative Methods · Quantitative Biology 2021-10-15 Bryan He , Matthew Thomson , Meena Subramaniam , Richard Perez , Chun Jimmie Ye , James Zou

Progress in anatomical 3D shape classification is limited by the complexity of mesh data and the lack of standardized benchmarks, highlighting the need for robust learning methods and reproducible evaluation. We introduce two key steps…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Tomáš Krsička , Tibor Kubík

Clustering analysis is fundamental in single-cell RNA sequencing (scRNA-seq) data analysis for elucidating cellular heterogeneity and diversity. Recent graph-based scRNA-seq clustering methods, particularly graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-07-15 Ping Xu , Pengfei Wang , Zhiyuan Ning , Meng Xiao , Min Wu , Yuanchun Zhou

Computer vision and machine learning tools offer an exciting new way for automatically analyzing and categorizing information from complex computer simulations. Here we design an ensemble machine learning framework that can independently…

Computer Vision and Pattern Recognition · Computer Science 2021-09-06 Maarja Bussov , Joonas Nättilä

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Genomics · Quantitative Biology 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

Geometrical structures and the internal local region relationship, such as symmetry, regular array, junction, etc., are essential for understanding a 3D shape. This paper proposes a point cloud feature extraction network named PointSCNet,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Xingye Chen , Yiqi Wu , Wenjie Xu , Jin Li , Huaiyi Dong , Yilin Chen

Accurate multi-class tubular modeling is critical for precise lesion localization and optimal treatment planning. Deep learning methods enable automated shape modeling by prioritizing volumetric overlap accuracy. However, the inherent…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Minghui Zhang , Yaoyu Liu , Xin You , Hanxiao Zhang , Yun Gu

Automated phenotyping of plants for breeding and plant studies promises to provide quantitative metrics on plant traits at a previously unattainable observation frequency. Developers of tools for performing high-throughput phenotyping are,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-04 Katherine Margaret Frances James , Karoline Heiwolt , Daniel James Sargent , Grzegorz Cielniak

A hierarchical ensemble pipeline is introduced to address anomaly detection in multivariate telemetry data provided by European Space Agency (ESA). The method integrates shapelet-based and statistical feature extraction, per-channel…

Machine Learning · Computer Science 2026-05-12 Lorenzo Riccardo Allegrini , Geremia Pompei

With the rapid adoption of machine learning techniques for large-scale applications in science and engineering comes the convergence of two grand challenges in visualization. First, the utilization of black box models (e.g., deep neural…

Since the PointNet was proposed, deep learning on point cloud has been the concentration of intense 3D research. However, existing point-based methods usually are not adequate to extract the local features and the spatial pattern of a point…

Computer Vision and Pattern Recognition · Computer Science 2020-04-01 Weikun Wu , Yan Zhang , David Wang , Yunqi Lei

Topology Bench is a comprehensive topology dataset designed to accelerate benchmarking studies in optical networks. The dataset, focusing on core optical networks, comprises publicly accessible and ready-to-use topologies, including (a) 105…

Networking and Internet Architecture · Computer Science 2024-11-08 Robin Matzner , Akanksha Ahuja , Rasoul Sadeghi , Michael Doherty , Alejandra Beghelli , Seb J. Savory , Polina Bayvel

We present a novel method for automated identification of putative cell types from single-cell RNA-seq (scRNA-seq) data. By iteratively applying a machine learning approach to an initial clustering of gene expression profiles of a given set…

Quantitative Methods · Quantitative Biology 2020-04-22 Zhichao Miao , Pablo Moreno , Ni Huang , Irene Papatheodorou , Alvis Brazma , Sarah A Teichmann

We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Benjamin Gutierrez Becker , Ignacio Sarasua , Christian Wachinger

Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells, which has given us insights into cell-cell communication, cell differentiation, and differential gene expression. However, analyzing scRNA-seq data is a…

Machine Learning · Computer Science 2023-06-27 Yuta Hozumi , Gu-Wei Wei

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

Training deep learning models on single-cell datasets with hundreds of millions of cells requires loading data from disk, as these datasets exceed available memory. While random sampling provides the data diversity needed for effective…

Machine Learning · Computer Science 2026-01-30 Davide D'Ascenzo , Sebastiano Cultrera di Montesano

Despite the breakthroughs in biomarker discovery facilitated by differential gene analysis, challenges remain, particularly at the single-cell level. Traditional methodologies heavily rely on user-supplied cell annotations, focusing on…

Genomics · Quantitative Biology 2023-12-29 Chenyu Liu , Yong Jin Kweon , Jun Ding

In high-dimensional and high-stakes contexts, ensuring both rigorous statistical guarantees and interpretability in feature extraction from complex tabular data remains a formidable challenge. Traditional methods such as Principal Component…

Machine Learning · Computer Science 2025-03-25 Xiaochen Zhang , Haoyi Xiong