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Reward finetuning has emerged as a promising approach to aligning foundation models with downstream objectives. Remarkable success has been achieved in the language domain by using reinforcement learning (RL) to maximize rewards that…

Machine Learning · Computer Science 2024-03-29 Fei Deng , Qifei Wang , Wei Wei , Matthias Grundmann , Tingbo Hou

This paper presents a controlled empirical study of biologically motivated local learning for handwritten digit recognition. We evaluate an STDP-inspired competitive proxy and a practical hybrid benchmark built on the same spiking…

Machine Learning · Computer Science 2026-03-03 Debjyoti Chakraborty

Discrete diffusion models have recently emerged as strong alternatives to autoregressive language models, matching their performance through large-scale training. However, inference-time control remains relatively underexplored. In this…

Machine Learning · Computer Science 2026-04-09 Meihua Dang , Jiaqi Han , Minkai Xu , Kai Xu , Akash Srivastava , Stefano Ermon

Autoregressive generative models naturally generate variable-length sequences, while non-autoregressive models struggle, often imposing rigid, token-wise structures. We propose Edit Flows, a non-autoregressive model that overcomes these…

Machine Learning · Computer Science 2025-11-13 Marton Havasi , Brian Karrer , Itai Gat , Ricky T. Q. Chen

We address the problem of fine-tuning diffusion models for reward-guided generation in biomolecular design. While diffusion models have proven highly effective in modeling complex, high-dimensional data distributions, real-world…

To fully leverage the capabilities of diffusion models, we are often interested in optimizing downstream reward functions during inference. While numerous algorithms for reward-guided generation have been recently proposed due to their…

Machine Learning · Computer Science 2025-04-18 Masatoshi Uehara , Xingyu Su , Yulai Zhao , Xiner Li , Aviv Regev , Shuiwang Ji , Sergey Levine , Tommaso Biancalani

Recent research has shown that fine-tuning diffusion models (DMs) with arbitrary rewards, including non-differentiable ones, is feasible with reinforcement learning (RL) techniques, enabling flexible model alignment. However, applying…

Machine Learning · Computer Science 2025-03-12 Zhiwei Jia , Yuesong Nan , Huixi Zhao , Gengdai Liu

Recent advances in one-step text-to-image generation have enabled real-time synthesis with remarkable efficiency and quality. Previous reinforcement learning methods for one-step generators combine image-space reward optimization with…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Junyi Wu , Weijian Luo , Haoyang Zheng , Ruizhe Zhang , Guang Lin

Differentially private (DP) synthetic data generation plays a pivotal role in developing large language models (LLMs) on private data, where data owners cannot provide eyes-on access to individual examples. Generating DP synthetic data…

Recently, DNA storage has surfaced as a promising alternative for data storage, presenting notable benefits in terms of storage capacity, cost-effectiveness in maintenance, and the capability for parallel replication. Mathematically, the…

Information Theory · Computer Science 2024-01-31 Yi Lu , Yun Ma , Chenghao Li , Xin Zhang , Guangxiang Si

Recent works have shown promising results of prompt tuning in stimulating pre-trained language models (PLMs) for natural language processing (NLP) tasks. However, to the best of our knowledge, existing works focus on prompt-tuning…

Computation and Language · Computer Science 2022-05-24 Yuan Yao , Bowen Dong , Ao Zhang , Zhengyan Zhang , Ruobing Xie , Zhiyuan Liu , Leyu Lin , Maosong Sun , Jianyong Wang

Low precision deep neural network (DNN) training is one of the most effective techniques for boosting DNNs' training efficiency, as it trims down the training cost from the finest bit level. While existing works mostly fix the model…

Machine Learning · Computer Science 2022-03-16 Zhongzhi Yu , Yonggan Fu , Shang Wu , Mengquan Li , Haoran You , Yingyan Lin

Large language models (LLMs) have achieved significant success across various domains. However, training these LLMs typically involves substantial memory and computational costs during both forward and backward propagation. While…

Machine Learning · Computer Science 2025-03-03 Sunghyeon Woo , Baeseong Park , Byeongwook Kim , Minjung Jo , Se Jung Kwon , Dongsuk Jeon , Dongsoo Lee

This paper introduces a novel framework for DNA sequence generation, comprising two key components: DiscDiff, a Latent Diffusion Model (LDM) tailored for generating discrete DNA sequences, and Absorb-Escape, a post-training algorithm…

Genomics · Quantitative Biology 2024-04-18 Zehui Li , Yuhao Ni , William A V Beardall , Guoxuan Xia , Akashaditya Das , Guy-Bart Stan , Yiren Zhao

Masked diffusion language models enable parallel token generation and offer improved decoding efficiency over autoregressive models. However, their performance degrades significantly when generating multiple tokens simultaneously, due to a…

Computation and Language · Computer Science 2026-05-12 Houxing Ren , Mingjie Zhan , Zimu Lu , Ke Wang , Yunqiao Yang , Haotian Hou , Junting Pan , Hongsheng Li

Diffusion-based Image Editing has achieved significant success in recent years. However, it remains challenging to achieve high-quality image editing while maintaining the background similarity without sacrificing speed or memory…

Graphics · Computer Science 2025-09-03 Siyi Liu , Weiming Chen , Yushun Tang , Zhihai He

Discrete diffusion models excel at visual synthesis but rely on slow, iterative decoding. Existing single-step distillation methods attempt to bypass this bottleneck, either by training auxiliary score networks that effectively double…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Chaoyang Wang , Yunhai Tong

Recent studies have demonstrated the strong empirical performance of diffusion models on discrete sequences across domains from natural language to biological sequence generation. For example, in the protein inverse folding task,…

Steering methods influence Large Language Model behavior by identifying semantic directions in hidden representations, but are typically realized through inference-time activation interventions that apply a fixed, global modification to the…

Computation and Language · Computer Science 2026-03-04 Chung-En Sun , Ge Yan , Zimo Wang , Tsui-Wei Weng

Discrete Diffusion Language Models (DLMs) offer a promising non-autoregressive alternative for text generation, yet effective mechanisms for inference-time control remain relatively underexplored. Existing approaches include sampling-level…

Computation and Language · Computer Science 2026-01-30 Eden Avrahami , Eliya Nachmani
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