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Scientific and environmental imagery often suffer from complex mixtures of noise related to the sensor and the environment. Existing restoration methods typically remove one degradation at a time, leading to cascading artifacts,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Rupa Kurinchi-Vendhan , Pratyusha Sharma , Antonio Torralba , Sara Beery

Nuclear Magnetic Resonance (NMR) spectroscopy is a central characterization method for molecular structure elucidation, yet interpreting NMR spectra to deduce molecular structures remains challenging due to the complexity of spectral data…

Chemical Physics · Physics 2025-07-15 Qingsong Yang , Binglan Wu , Xuwei Liu , Bo Chen , Wei Li , Gen Long , Xin Chen , Mingjun Xiao

Faithfully representing chemical environments is essential for describing materials and molecules with machine learning approaches. Here, we present a systematic classification of these representations and then investigate: (i) the…

Materials Science · Physics 2020-10-28 Berk Onat , Christoph Ortner , James R. Kermode

Molecular property prediction, crucial for early drug candidate screening and optimization, has seen advancements with deep learning-based methods. While deep learning-based methods have advanced considerably, they often fall short in fully…

Biomolecules · Quantitative Biology 2024-07-01 Taojie Kuang , Yiming Ren , Zhixiang Ren

Molecular representation learning (MRL) is a key step to build the connection between machine learning and chemical science. In particular, it encodes molecules as numerical vectors preserving the molecular structures and features, on top…

Quantitative Methods · Quantitative Biology 2023-11-30 Zhichun Guo , Kehan Guo , Bozhao Nan , Yijun Tian , Roshni G. Iyer , Yihong Ma , Olaf Wiest , Xiangliang Zhang , Wei Wang , Chuxu Zhang , Nitesh V. Chawla

The requirement for accelerated and quantitatively accurate screening of nuclear magnetic resonance spectra across the small molecules chemical compound space is two-fold: (1) a robust `local' machine learning (ML) strategy capturing the…

Chemical Physics · Physics 2020-12-04 Amit Gupta , Sabyasachi Chakraborty , Raghunathan Ramakrishnan

Accurate prediction of nuclear magnetic resonance (NMR) chemical shifts is fundamental to spectral analysis and molecular structure elucidation, yet existing machine learning methods rely on limited, labor-intensive atom-assigned datasets.…

Machine Learning · Computer Science 2026-01-27 Yongqi Jin , Yecheng Wang , Jun-jie Wang , Rong Zhu , Guolin Ke , Weinan E

Cross-modal retrieval (CMR) has been extensively applied in various domains, such as multimedia search engines and recommendation systems. Most existing CMR methods focus on image-to-text retrieval, whereas audio-to-text retrieval, a less…

Sound · Computer Science 2023-09-19 Kaiyi Luo , Xulong Zhang , Jianzong Wang , Huaxiong Li , Ning Cheng , Jing Xiao

Learning scientific document representations can be substantially improved through contrastive learning objectives, where the challenge lies in creating positive and negative training samples that encode the desired similarity semantics.…

Computation and Language · Computer Science 2022-10-20 Malte Ostendorff , Nils Rethmeier , Isabelle Augenstein , Bela Gipp , Georg Rehm

The applications of machine learning techniques to chemistry and materials science become more numerous by the day. The main challenge is to devise representations of atomic systems that are at the same time complete and concise, so as to…

Chemical Physics · Physics 2025-10-06 Michael J. Willatt , Felix Musil , Michele Ceriotti

Real-scene image super-resolution aims to restore real-world low-resolution images into their high-quality versions. A typical RealSR framework usually includes the optimization of multiple criteria which are designed for different image…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Yukai Shi , Hao Li , Sen Zhang , Zhijing Yang , Xiao Wang

Precision medicine fundamentally aims to establish causality between dysregulated biochemical mechanisms and cancer subtypes. Omics-based cancer subtyping has emerged as a revolutionary approach, as different level of omics records the…

Genomics · Quantitative Biology 2023-08-25 Ziwei Yang , Zheng Chen , Yasuko Matsubara , Yasushi Sakurai

Recent advances in Large Language Models (LLMs) have stimulated a surge of research aimed at extending their applications to the visual domain. While these models exhibit promise in generating abstract image captions and facilitating…

Computation and Language · Computer Science 2023-10-27 Geewook Kim , Hodong Lee , Daehee Kim , Haeji Jung , Sanghee Park , Yoonsik Kim , Sangdoo Yun , Taeho Kil , Bado Lee , Seunghyun Park

Accurate molecular property prediction requires integrating complementary information from molecular structure and chemical semantics. In this work, we propose LGM-CL, a local-global multimodal contrastive learning framework that jointly…

Machine Learning · Computer Science 2026-02-02 Xiayu Liu , Zhengyi Lu , Yunhong Liao , Chan Fan , Hou-biao Li

Contrastive learning (CL) has been successful as a powerful representation learning method. In this work we propose CLIM: Contrastive Learning with mutual Information Maximization, to explore the potential of CL on cross-domain sentiment…

Computation and Language · Computer Science 2020-11-13 Tian Li , Xiang Chen , Shanghang Zhang , Zhen Dong , Kurt Keutzer

Machine learning (ML) can be used to construct surrogate models for the fast prediction of a property of interest. ML can thus be applied to chemical projects, where the usual experimentation or calculation techniques can take hours or days…

Recent work has shown the potential of graph neural networks to efficiently predict material properties, enabling high-throughput screening of materials. Training these models, however, often requires large quantities of labelled data,…

Machine Learning · Computer Science 2022-11-28 Teddy Koker , Keegan Quigley , Will Spaeth , Nathan C. Frey , Lin Li

For a widely-studied data model and general loss and sample-hardening functions we prove that the losses of Supervised Contrastive Learning (SCL), Hard-SCL (HSCL), and Unsupervised Contrastive Learning (UCL) are minimized by representations…

Machine Learning · Computer Science 2025-05-08 Ruijie Jiang , Thuan Nguyen , Shuchin Aeron , Prakash Ishwar

Contrastive learning based on instance discrimination trains model to discriminate different transformations of the anchor sample from other samples, which does not consider the semantic similarity among samples. This paper proposes a new…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Hao Li , Xiaopeng Zhang , Hongkai Xiong

Deep representations have shown promising performance when transferred to downstream tasks in a black-box manner. Yet, their inherent lack of interpretability remains a significant challenge, as these features are often opaque to human…

Machine Learning · Computer Science 2024-04-24 Yifei Wang , Qi Zhang , Yaoyu Guo , Yisen Wang