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Concept Bottleneck Models (CBMs) map the black-box visual representations extracted by deep neural networks onto a set of interpretable concepts and use the concepts to make predictions, enhancing the transparency of the decision-making…

Machine Learning · Computer Science 2024-04-18 Chenming Shang , Shiji Zhou , Hengyuan Zhang , Xinzhe Ni , Yujiu Yang , Yuwang Wang

Deep neural networks have achieved remarkable success in computer vision; however, their black-box nature in decision-making limits interpretability and trust, particularly in safety-critical applications. Interpretability is crucial in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Ran Eisenberg , Amit Rozner , Ethan Fetaya , Ofir Lindenbaum

Large, publicly available clinical datasets have emerged as a novel resource for understanding disease heterogeneity and to explore personalization of therapy. These datasets are derived from data not originally collected for research…

Machine Learning · Computer Science 2025-08-14 Anish Narain , Ritam Majumdar , Nikita Narayanan , Dominic Marshall , Sonali Parbhoo

Vision-Language Models (VLMs) have enabled interpretable medical diagnosis by integrating visual perception with linguistic reasoning. Yet, existing medical chain-of-thought (CoT) models lack explicit mechanisms to represent and enforce…

Artificial Intelligence · Computer Science 2026-05-29 Jianxin Lin , Chunzheng Zhu , Peter J. Kneuertz , Yunfei Bai , Yuan Xue

Models based on human-understandable concepts have received extensive attention to improve model interpretability for trustworthy artificial intelligence in the field of medical image analysis. These methods can provide convincing…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Hongmei Wang , Junlin Hou , Hao Chen

In recent years, Visual Anomaly Detection (VAD) has gained significant attention due to its ability to identify defects using only normal images during training. Many VAD models work without supervision but are still able to provide visual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Arianna Stropeni , Valentina Zaccaria , Francesco Borsatti , Davide Dalle Pezze , Manuel Barusco , Gian Antonio Susto

Concept Bottleneck Models (CBMs) have emerged as a prominent paradigm for interpretable deep learning, learning by grounding predictions in human-understandable concepts. However, their practical deployment is hindered by the high cost of…

Machine Learning · Computer Science 2026-05-29 Ziye Chen , Hongbin Lin , Jie Li , Lijie Hu

Causal reasoning provides a language to ask important interventional and counterfactual questions beyond purely statistical association. In medical imaging, for example, we may want to study the causal effect of genetic, environmental, or…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Rajat Rasal , Daniel C. Castro , Nick Pawlowski , Ben Glocker

Deep learning-based medical image classification techniques are rapidly advancing in medical image analysis, making it crucial to develop accurate and trustworthy models that can be efficiently deployed across diverse clinical scenarios.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hangzhou He , Jiachen Tang , Lei Zhu , Kaiwen Li , Yanye Lu

Textual Concept Bottleneck Models (TCBMs) are interpretable-by-design models for text classification that predict a set of salient concepts before making the final prediction. This paper proposes Complete Textual Concept Bottleneck Model…

Computation and Language · Computer Science 2025-05-29 Milan Bhan , Yann Choho , Pierre Moreau , Jean-Noel Vittaut , Nicolas Chesneau , Marie-Jeanne Lesot

Automatic chest X-ray report generation is an important area of research aimed at improving diagnostic accuracy and helping doctors make faster decisions. Current AI models are good at finding correlations (or patterns) in medical images.…

Machine Learning · Computer Science 2025-12-16 Satyam Kumar

We propose an automated genomic interpretation module that transforms raw DNA sequences into actionable, interpretable decisions suitable for integration into medical automation and robotic systems. Our framework combines Chaos Game…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zijun Li , Jinchang Zhang , Ming Zhang , Guoyu Lu

Concept Bottleneck Models (CBMs) aim to improve interpretability in Deep Learning by structuring predictions through human-understandable concepts, but they provide no way to verify whether learned concepts align with the human's intended…

Machine Learning · Computer Science 2026-05-22 Stefano Colamonaco , David Debot , Pietro Barbiero , Giuseppe Marra

Concept Bottleneck Models (CBMs) enhance interpretability by predicting human-understandable concepts as intermediate representations. However, existing CBMs often suffer from input-to-concept mapping bias and limited controllability, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Gaoxiang Huang , Songning Lai , Yutao Yue

Concept Bottleneck Models (CBMs) enhance interpretability by introducing a layer of human-understandable concepts between inputs and predictions. While recent methods automate concept generation using Large Language Models (LLMs) and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Delong Zhao , Qiang Huang , Di Yan , Yiqun Sun , Jun Yu

Continual learning (CL) aims to enable learning systems to acquire new knowledge constantly without forgetting previously learned information. CL faces the challenge of mitigating catastrophic forgetting while maintaining interpretability…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Lu Yu , Haoyu Han , Zhe Tao , Hantao Yao , Changsheng Xu

Advancements in foundation models (FMs) have led to a paradigm shift in machine learning. The rich, expressive feature representations from these pre-trained, large-scale FMs are leveraged for multiple downstream tasks, usually via…

Machine Learning · Computer Science 2024-12-19 Jihye Choi , Jayaram Raghuram , Yixuan Li , Somesh Jha

Concept Bottleneck Models (CBMs) have become a popular approach to enable interpretability in neural networks by constraining classifier inputs to a set of human-understandable concepts. While effective, current models embed concepts in…

Machine Learning · Computer Science 2026-05-13 Daniel Uyterlinde , Swasti Shreya Mishra , Pascal Mettes

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in…

Artificial Intelligence · Computer Science 2025-05-22 Ziqing Fan , Cheng Liang , Chaoyi Wu , Ya Zhang , Yanfeng Wang , Weidi Xie

Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding