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Causal structure learning is a key problem in many domains. Causal structures can be learnt by performing experiments on the system of interest. We address the largely unexplored problem of designing a batch of experiments that each…

Machine Learning · Computer Science 2021-11-25 Scott Sussex , Andreas Krause , Caroline Uhler

We study the identification of causal effects in the presence of different types of constraints (e.g., logical constraints) in addition to the causal graph. These constraints impose restrictions on the models (parameterizations) induced by…

Artificial Intelligence · Computer Science 2025-10-15 Yizuo Chen , Adnan Darwiche

Causal discovery is crucial for understanding complex systems and informing decisions. While observational data can uncover causal relationships under certain assumptions, it often falls short, making active interventions necessary. Current…

Machine Learning · Computer Science 2024-06-18 Yuxuan Wang , Mingzhou Liu , Xinwei Sun , Wei Wang , Yizhou Wang

Causal discovery from observational and interventional data is challenging due to limited data and non-identifiability: factors that introduce uncertainty in estimating the underlying structural causal model (SCM). Selecting experiments…

Machine Learning · Computer Science 2022-10-24 Panagiotis Tigas , Yashas Annadani , Andrew Jesson , Bernhard Schölkopf , Yarin Gal , Stefan Bauer

Identifying the effects of causes and causes of effects is vital in virtually every scientific field. Often, however, the needed probabilities may not be fully identifiable from the data sources available. This paper shows how partial…

Artificial Intelligence · Computer Science 2023-01-31 Ang Li , Scott Mueller , Judea Pearl

In many scientific experiments, the data annotating cost constraints the pace for testing novel hypotheses. Yet, modern machine learning pipelines offer a promising solution, provided their predictions yield correct conclusions. We focus on…

In this paper, we compute the tightest possible bounds on the probability that the optimal value of a combinatorial optimization problem in maximization form with a random objective exceeds a given number, assuming only knowledge of the…

Optimization and Control · Mathematics 2022-11-24 Divya Padmanabhan , Selin Damla Ahipasaoglu , Arjun Ramachandra , Karthik Natarajan

One of the most common mistakes made when performing data analysis is attributing causal meaning to regression coefficients. Formally, a causal effect can only be computed if it is identifiable from a combination of observational data and…

Artificial Intelligence · Computer Science 2019-10-31 Daniel Kumor , Bryant Chen , Elias Bareinboim

High-throughput gene perturbation experiments can test several genetic interventions in parallel, yet experimental budgets remain limited. A central goal is hit discovery: identifying as many perturbations as possible whose phenotypic…

Machine Learning · Computer Science 2026-05-12 Andrea Rubbi , Arpit Merchant , Samuel Ogden , Amir Akbarnejad , Pietro Liò , Sattar Vakili , Mo Lotfollahi

Interdiction problems ask about the worst-case impact of a limited change to an underlying optimization problem. They are a natural way to measure the robustness of a system, or to identify its weakest spots. Interdiction problems have been…

Optimization and Control · Mathematics 2015-11-10 Stephen R. Chestnut , Rico Zenklusen

Individual treatment effects are not point-identified from data. The Probability of Necessity and Sufficiency (PNS) circumvents this limitation by characterizing individual-level causality through intersection bounds derived from combined…

Machine Learning · Statistics 2026-05-11 Gandharv Patil , Keyi Tang , Raquel Aoki , Leo Guelman

We consider the minimum cost intervention design problem: Given the essential graph of a causal graph and a cost to intervene on a variable, identify the set of interventions with minimum total cost that can learn any causal graph with the…

Machine Learning · Computer Science 2018-10-30 Erik M. Lindgren , Murat Kocaoglu , Alexandros G. Dimakis , Sriram Vishwanath

Selective inference (SI) has been actively studied as a promising framework for statistical hypothesis testing for data-driven hypotheses. The basic idea of SI is to make inferences conditional on an event that a hypothesis is selected. In…

Machine Learning · Statistics 2023-12-29 Tomohiro Shiraishi , Daiki Miwa , Vo Nguyen Le Duy , Ichiro Takeuchi

Causal inference methods are widely applied in the fields of medicine, policy, and economics. Central to these applications is the estimation of treatment effects to make decisions. Current methods make binary yes-or-no decisions based on…

Machine Learning · Computer Science 2020-04-24 Will Y. Zou , Smitha Shyam , Michael Mui , Mingshi Wang , Jan Pedersen , Zoubin Ghahramani

Scientific hypotheses typically concern specific aspects of complex, imperfectly understood or entirely unknown mechanisms, such as the effect of gene expression levels on phenotypes or how microbial communities influence environmental…

Methodology · Statistics 2025-03-05 Elisabeth Ailer , Niclas Dern , Jason Hartford , Niki Kilbertus

We conjecture that the worst case number of experiments necessary and sufficient to discover a causal graph uniquely given its observational Markov equivalence class can be specified as a function of the largest clique in the Markov…

Artificial Intelligence · Computer Science 2012-06-18 Frederick Eberhardt

The No Unmeasured Confounding Assumption is widely used to identify causal effects in observational studies. Recent work on proximal inference has provided alternative identification results that succeed even in the presence of unobserved…

Machine Learning · Statistics 2022-10-17 Benjamin Kompa , David R. Bellamy , Thomas Kolokotrones , James M. Robins , Andrew L. Beam

We study the problem of set discovery where given a few example tuples of a desired set, we want to find the set in a collection of sets. A challenge is that the example tuples may not uniquely identify a set, and a large number of…

Databases · Computer Science 2022-10-05 Arif Hasnat , Davood Rafiei

Identifying cause-effect relations among variables is a key step in the decision-making process. While causal inference requires randomized experiments, researchers and policymakers are increasingly using observational studies to test…

Optimization and Control · Mathematics 2021-11-22 Md Saiful Islam , Md Sarowar Morshed , Md. Noor-E-Alam

Causal knowledge can be used to support decision-making problems. This has been recognized in the causal bandits literature, where a causal (multi-armed) bandit is characterized by a causal graphical model and a target variable. The arms…

Machine Learning · Computer Science 2025-10-14 Francisco N. F. Q. Simoes , Itai Feigenbaum , Mehdi Dastani , Thijs van Ommen