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A scalable and robust 3D tissue transcriptomics profile can enable a holistic understanding of tissue organization and provide deeper insights into human biology and disease. Most predictive algorithms that infer ST directly from histology…

It remains challenging to assess driver fatigue from untrimmed videos under constrained computational budgets, due to the difficulty of modeling long-range temporal dependencies in subtle facial expressions. Some existing approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Changdao Chen

We evaluate a co-evolutionary calibration framework for the Heston model in which a genetic algorithm (GA) over parameters is coupled to an evolving neural inverse map from option surfaces to parameters. While GA-history sampling can reduce…

Pricing of Securities · Quantitative Finance 2025-12-04 Julian Gutierrez

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

Traffic forecasting, a crucial application of spatio-temporal graph (STG) learning, has traditionally relied on deterministic models for accurate point estimations. Yet, these models fall short of quantifying future uncertainties. Recently,…

Machine Learning · Computer Science 2024-08-08 Lequan Lin , Dai Shi , Andi Han , Junbin Gao

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Spatial intelligence is the ability of a machine to perceive, reason, and act in three dimensions within space and time. Recent advancements in large-scale auto-regressive models have demonstrated remarkable capabilities across various…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Junyi Chen , Di Huang , Weicai Ye , Wanli Ouyang , Tong He

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context.…

Applications · Statistics 2025-02-20 Bencong Zhu , Alberto Cassese , Marina Vannucci , Michele Guindani , Qiwei Li

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

Methodology · Statistics 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

Transformer Semantic Genetic Programming (TSGP) is a semantic search approach that uses a pre-trained transformer model as a variation operator to generate offspring programs with high semantic similarity to a given parent. Unlike other…

Machine Learning · Computer Science 2026-05-01 Philipp Anthes , Dominik Sobania , Franz Rothlauf

Spatiotemporal learning is challenging due to the intricate interplay between spatial and temporal dependencies, the high dimensionality of the data, and scalability constraints. These challenges are further amplified in scientific domains,…

Machine Learning · Computer Science 2025-04-17 David Keetae Park , Xihaier Luo , Guang Zhao , Seungjun Lee , Miruna Oprescu , Shinjae Yoo

Transformer-based models have achieved remarkable success in natural language and vision tasks, but their application to gene expression analysis remains limited due to data sparsity, high dimensionality, and missing values. We present…

Machine Learning · Computer Science 2025-04-15 Shuai Jiang , Saeed Hassanpour

Convolutional neural networks have been widely applied to hyperspectral image classification. However, traditional convolutions can not effectively extract features for objects with irregular distributions. Recent methods attempt to address…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Di Wang , Bo Du , Liangpei Zhang

A comprehensive three-dimensional (3D) map of tissue architecture and gene expression is crucial for illuminating the complexity and heterogeneity of tissues across diverse biomedical applications. However, most spatial transcriptomics (ST)…

Hyperspectral image denoising faces the challenge of multi-dimensional coupling of spatially non-uniform noise and spectral correlation interference. Existing deep learning methods mostly focus on RGB images and struggle to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Haoyue Li , Di Wu

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi

Forecasting high-resolution land subsidence is a critical yet challenging task due to its complex, non-linear dynamics. While standard architectures like ConvLSTM often fail to model long-range dependencies, we argue that a more fundamental…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wendong Yao , Binhua Huang , Soumyabrata Dev

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

In standard genetic programming (stdGP), solutions are varied by modifying their syntax, with uncertain effects on their semantics. Geometric-semantic genetic programming (GSGP), a popular variant of GP, effectively searches the semantic…

Neural and Evolutionary Computing · Computer Science 2025-01-31 Philipp Anthes , Dominik Sobania , Franz Rothlauf

In recent years, there has been a rapid development of spatio-temporal prediction techniques in response to the increasing demands of traffic management and travel planning. While advanced end-to-end models have achieved notable success in…

Machine Learning · Computer Science 2023-11-09 Zhonghang Li , Lianghao Xia , Yong Xu , Chao Huang