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Complex spatial and temporal patterns of gene expression underlie embryo differentiation, yet methods do not yet exist for the efficient genome-wide determination of spatial expression patterns during development. In situ imaging of…

Genomics · Quantitative Biology 2013-08-15 Peter A. Combs , Michael B. Eisen

Accurate hand gesture prediction is crucial for effective upper-limb prosthetic limbs control. As the high flexibility and multiple degrees of freedom exhibited by human hands, there has been a growing interest in integrating deep networks…

Human-Computer Interaction · Computer Science 2026-04-07 Wenjuan Zhong , Yuyang Zhang , Peiwen Fu , Wenxuan Xiong , Mingming Zhang

Glaucoma is one of the major eye diseases that leads to progressive optic nerve fiber damage and irreversible blindness, afflicting millions of individuals. Glaucoma forecast is a good solution to early screening and intervention of…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Xikai Yang , Jian Wu , Xi Wang , Yuchen Yuan , Ning Li Wang , Pheng-Ann Heng

Search-Based Software Testing (SBST) automates test input generation but is frequently hindered by challenging fitness landscapes characterized by numerous deceptive local optima that impede search progress, as well as extended plateaus…

Software Engineering · Computer Science 2026-04-13 Jeongjin Han , Seunghoon Sim , Jian Lee , Seongyoon Park

While pathology foundation models have transformed cancer image analysis, they often lack integration with molecular data at single-cell resolution, limiting their utility for precision oncology. Here, we present PAST, a pan-cancer…

Quantitative Methods · Quantitative Biology 2025-07-10 Changchun Yang , Haoyang Li , Yushuai Wu , Yilan Zhang , Yifeng Jiao , Yu Zhang , Rihan Huang , Yuan Cheng , Yuan Qi , Xin Guo , Xin Gao

High-quality 3D texture generation remains a fundamental challenge due to the view-inconsistency inherent in current mainstream multi-view diffusion pipelines. Existing representations either rely on UV maps, which suffer from distortion…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Ziteng Lu , Yushuang Wu , Chongjie Ye , Yuda Qiu , Jing Shao , Xiaoyang Guo , Jiaqing Zhou , Tianlei Hu , Kun Zhou , Xiaoguang Han

Predicting the risk of developing breast cancer is an important clinical tool to guide early intervention and tailoring personalized screening strategies. Early risk models have limited performance and recently machine learning-based…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Zhengbo Zhou , Dooman Arefan , Margarita Zuley , Jules Sumkin , Shandong Wu

Spatial transcriptomics reveals gene expression patterns within tissue context, enabling precision oncology applications such as treatment response prediction, but its high cost and technical complexity limit clinical adoption. Predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Won June Cho , Hongjun Yoon , Daeky Jeong , Hyeongyeol Lim , Yosep Chong

In Earth sciences, unobserved factors exhibit non-stationary spatial distributions, causing the relationships between features and targets to display spatial heterogeneity. In geographic machine learning tasks, conventional statistical…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Siqi Du , Hongsheng Huang , Kaixin Shen , Ziqi Liu , Shengjun Tang

Learning time-series representations for discriminative tasks, such as classification and regression, has been a long-standing challenge in the healthcare domain. Current pre-training methods are limited in either unidirectional next-token…

Artificial Intelligence · Computer Science 2024-08-27 Ziyang Song , Qincheng Lu , He Zhu , David Buckeridge , Yue Li

Accurate forecasting of spatiotemporal data remains challenging due to complex spatial dependencies and temporal dynamics. The inherent uncertainty and variability in such data often render deterministic models insufficient, prompting a…

Machine Learning · Computer Science 2024-11-05 Mingze Gong , Lei Chen , Jia Li

Fine-grained visual classification (FGVC) remains highly sensitive to geometric variability, where objects appear under arbitrary orientations, scales, and perspective distortions. While equivariant architectures address this issue, they…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Johann Schmidt , Sebastian Stober

Spatial boundaries, such as ecological transitions or climatic regime interfaces, capture steep environmental gradients, and shifts in their structure can signal emerging environmental changes. Quantifying uncertainty in spatial boundary…

Applications · Statistics 2025-12-18 Stephen Tivenan , Indranil Sahoo , Yanjun Qian

We introduce a nonstationary spatio-temporal statistical model for gridded data on the sphere. The model specifies a computationally convenient covariance structure that depends on heterogeneous geography. Widely used statistical models on…

Applications · Statistics 2016-02-25 Stefano Castruccio , Joseph Guinness

Inferring spatially resolved gene expression from histology images offers a cost-effective complement to spatial transcriptomics (ST). However, existing methods reduce this task to a simple morphology-to-expression mapping, where visual…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Spatial transcriptomics allows researchers to visualize and analyze gene expression within the precise location of tissues or cells. It provides spatially resolved gene expression data but often lacks cellular resolution, necessitating cell…

Quantitative Methods · Quantitative Biology 2025-10-27 Jiasen Zhang , Xi Qiao , Liangliang Zhang , Weihong Guo

Facial expression spotting is a significant but challenging task in facial expression analysis. The accuracy of expression spotting is affected not only by irrelevant facial movements but also by the difficulty of perceiving subtle motions…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Yicheng Deng , Hideaki Hayashi , Hajime Nagahara

Motivation: Traditional image attribution methods struggle to satisfactorily explain predictions of neural networks. Prediction explanation is important, especially in medical imaging, for avoiding the unintended consequences of deploying…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Joseph Paul Cohen , Rupert Brooks , Sovann En , Evan Zucker , Anuj Pareek , Matthew P. Lungren , Akshay Chaudhari

Unsupervised domain adaptation techniques, extensively studied in hyperspectral image (HSI) classification, aim to use labeled source domain data and unlabeled target domain data to learn domain invariant features for cross-scene…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Jie Feng , Tianshu Zhang , Junpeng Zhang , Ronghua Shang , Weisheng Dong , Guangming Shi , Licheng Jiao

Spatio-Temporal Graph (STG) forecasting is a fundamental task in many real-world applications. Spatio-Temporal Graph Neural Networks have emerged as the most popular method for STG forecasting, but they often struggle with temporal…

Machine Learning · Computer Science 2023-09-26 Yutong Xia , Yuxuan Liang , Haomin Wen , Xu Liu , Kun Wang , Zhengyang Zhou , Roger Zimmermann
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