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Differentiating between the two main subtypes of Inflammatory Bowel Disease (IBD): Crohns disease (CD) and ulcerative colitis (UC) is a persistent clinical challenge due to overlapping presentations. This study introduces a novel…

Genomics · Quantitative Biology 2026-01-14 Myles Joshua Toledo Tan , Maria Kapetanaki , Panayiotis V. Benos

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Crohn's Disease (CD) and Ulcerative Colitis (UC) are the two main Inflammatory Bowel Disease (IBD) types. We developed deep learning models to identify histological disease features for both CD and UC using only endoscopic labels. We…

Automated diagnosis from chest CT has improved considerably with deep learning, but models trained on skewed datasets tend to perform unevenly across patient demographics. However, the situation is worse than simple demographic bias. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Justin Li , Daniel Ding , Asmita Yuki Pritha , Aryana Hou , Xin Wang , Shu Hu

Deep graph clustering, which aims to reveal the underlying graph structure and divide the nodes into different clusters without human annotations, is a fundamental yet challenging task. However, we observed that the existing methods suffer…

Computer Vision and Pattern Recognition · Computer Science 2022-02-28 Yue Liu , Sihang Zhou , Xinwang Liu , Wenxuan Tu , Xihong Yang

Single-cell RNA sequencing (scRNA-seq) has the potential to provide powerful, high-resolution signatures to inform disease prognosis and precision medicine. This paper takes an important first step towards this goal by developing an…

Quantitative Methods · Quantitative Biology 2021-10-15 Bryan He , Matthew Thomson , Meena Subramaniam , Richard Perez , Chun Jimmie Ye , James Zou

Reviewing radiology reports in emergency departments is an essential but laborious task. Timely follow-up of patients with abnormal cases in their radiology reports may dramatically affect the patient's outcome, especially if they have been…

Computation and Language · Computer Science 2018-12-06 Hamed Hassanzadeh , Mahnoosh Kholghi , Anthony Nguyen , Kevin Chu

This study proposes an efficient neural network with convolutional layers to classify significantly class-imbalanced clinical data. The data are curated from the National Health and Nutritional Examination Survey (NHANES) with the goal of…

Quantitative Methods · Quantitative Biology 2020-04-24 Aniruddha Dutta , Tamal Batabyal , Meheli Basu , Scott T. Acton

Single-cell RNA sequencing (scRNA-seq) is essential for unraveling cellular heterogeneity and diversity, offering invaluable insights for bioinformatics advancements. Despite its potential, traditional clustering methods in scRNA-seq data…

Machine Learning · Computer Science 2025-10-01 Ping Xu , Zhiyuan Ning , Meng Xiao , Guihai Feng , Xin Li , Yuanchun Zhou , Pengfei Wang

The automated Interstitial Lung Diseases (ILDs) classification technique is essential for assisting clinicians during the diagnosis process. Detecting and classifying ILDs patterns is a challenging problem. This paper introduces an…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Masum Shah Junayed , Afsana Ahsan Jeny , Md Baharul Islam , Ikhtiar Ahmed , A F M Shahen Shah

Differentiating between Intestinal Tuberculosis (ITB) and Crohn's Disease (CD) poses a significant clinical challenge due to their similar symptoms, clinical presentations, and imaging features. This study leverages Computed Tomography…

Image and Video Processing · Electrical Eng. & Systems 2024-10-25 Shashwat Gupta , L. Gokulnath , Akshan Aggarwal , Mahim Naz , Rajnikanth Yadav , Priyanka Bagade

Intelligent analysis of medical imaging plays a crucial role in assisting clinical diagnosis, especially for identifying subtle pathological features. This paper introduces a novel multi-branch ConvNeXt architecture designed specifically…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Irash Perera , Uthayasanker Thayasivam

Crops hold paramount significance as they serve as the primary provider of energy, nutrition, and medicinal benefits for the human population. Plant diseases, however, can negatively affect leaves during agricultural cultivation, resulting…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Shashwat Jha , Vishvaditya Luhach , Gauri Shanker Gupta , Beependra Singh

Molecular subtypes of colorectal cancer (CRC) significantly influence treatment decisions. While convolutional neural networks (CNNs) have recently been introduced for automated CRC subtype identification using H&E stained histopathological…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Hadar Hezi , Daniel Shats , Daniel Gurevich , Yosef E. Maruvka , Moti Freiman

Following recent advancements in computer-aided detection and diagnosis systems for colonoscopy, the automated reporting of colonoscopy procedures is set to further revolutionize clinical practice. A crucial yet underexplored aspect in the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Carlo Biffi , Giorgio Roffo , Pietro Salvagnini , Andrea Cherubini

Evaluating long-context radiology report generation is challenging. NLG metrics fail to capture clinical correctness, while LLM-based metrics often lack generalizability. Clinical accuracy metrics are more relevant but are sensitive to…

Computation and Language · Computer Science 2025-05-26 Ibrahim Ethem Hamamci , Sezgin Er , Suprosanna Shit , Hadrien Reynaud , Bernhard Kainz , Bjoern Menze

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…

Bladder cancer is one of the most prevalent malignancies worldwide, with a recurrence rate of up to 78%, necessitating accurate post-operative monitoring for effective patient management. Multi-sequence contrast-enhanced MRI is commonly…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xueyang Li , Zongren Wang , Yuliang Zhang , Zixuan Pan , Yu-Jen Chen , Nishchal Sapkota , Gelei Xu , Danny Z. Chen , Yiyu Shi

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

Machine Learning · Computer Science 2024-11-28 Huifa Li , Jie Fu , Xinpeng Ling , Zhiyu Sun , Kuncan Wang , Zhili Chen
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