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Decision support systems for classification tasks are predominantly designed to predict the value of the ground truth labels. However, since their predictions are not perfect, these systems also need to make human experts understand when…

Machine Learning · Computer Science 2024-07-17 Eleni Straitouri , Manuel Gomez Rodriguez

Artificial intelligence (AI) has huge potential to improve the health and well-being of people, but adoption in clinical practice is still limited. Lack of transparency is identified as one of the main barriers to implementation, as…

Artificial Intelligence · Computer Science 2021-01-06 Aniek F. Markus , Jan A. Kors , Peter R. Rijnbeek

The adoption of Artificial Intelligence (AI) in the healthcare service industry presents numerous ethical challenges, yet current frameworks often fail to offer a comprehensive, empirical understanding of the multidimensional factors…

Artificial Intelligence · Computer Science 2025-05-06 Prathamesh Muzumdar , Apoorva Muley , Kuldeep Singh , Sumanth Cheemalapati

Clinical practice guidelines (CPGs) encode evidence-based decision logic that clinicians apply by evaluating patient variables, conditional criteria, and recommendation rules. However, existing methods often use CPGs as free-text training…

Artificial Intelligence · Computer Science 2026-05-27 Yuhao Shen , Lang Cao , Simo Du , Yuqing Wang , Juexiao Zhou , Hao Peng , Yue Guo

In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Zihao Jin , Xiaodan Xing , Simon Walsh , Guang Yang

Large language models (LLMs) are increasingly being used for complex research tasks such as literature review, idea generation, and scientific paper analysis, yet their ability to truly understand and process the intricate relationships…

Computation and Language · Computer Science 2025-06-11 Shashidhar Reddy Javaji , Yupeng Cao , Haohang Li , Yangyang Yu , Nikhil Muralidhar , Zining Zhu

Bias in medical artificial intelligence is conventionally viewed as a defect requiring elimination. However, human reasoning inherently incorporates biases shaped by education, culture, and experience, suggesting their presence may be…

Artificial Intelligence · Computer Science 2026-03-05 Farhad Abtahi , Mehdi Astaraki , Fernando Seoane

Clinical decision support systems combine knowledge and data from a variety of sources, represented by quantitative models based on stochastic methods, or qualitative based rather on expert heuristics and deductive reasoning. At the same…

Artificial Intelligence · Computer Science 2020-01-22 Ying Shen , Jacquet-Andrieu Armelle , Joël Colloc

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Large language models have achieved strong performance on medical reasoning benchmarks, yet their deployment in clinical settings demands rigorous verification to ensure factual accuracy. While reward models offer a scalable approach for…

Artificial Intelligence · Computer Science 2026-01-29 Hang Zhang , Ruheng Wang , Yuelyu Ji , Mingu Kwak , Xizhi Wu , Chenyu Li , Li Zhang , Wenqi Shi , Yifan Peng , Yanshan Wang

LLMs enable qualitative coding at large scale, but assessing reliability remains challenging where human experts seldom agree. We investigate confidence-diversity calibration as a quality assessment framework for accessible coding tasks…

Machine Learning · Computer Science 2025-08-19 Zhilong Zhao , Yindi Liu

We describe and compare design choices for meta-predicate semantics, as found in representative Prolog module systems and in Logtalk. We look at the consequences of these design choices from a pragmatic perspective, discussing explicit…

Programming Languages · Computer Science 2010-09-21 Paulo Moura

The paper introduces a framework for the evaluation of the encoding of factual scientific knowledge, designed to streamline the manual evaluation process typically conducted by domain experts. Inferring over and extracting information from…

Computation and Language · Computer Science 2024-10-21 Magdalena Wysocka , Oskar Wysocki , Maxime Delmas , Vincent Mutel , Andre Freitas

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

Logical frameworks based on intuitionistic or linear logics with higher-type quantification have been successfully used to give high-level, modular, and formal specifications of many important judgments in the area of programming languages…

Logic in Computer Science · Computer Science 2007-05-23 Raymond C. McDowell , Dale A. Miller

Large Language Models (LLMs) hold significant promise for improving clinical decision support and reducing physician burnout by synthesizing complex, longitudinal cancer Electronic Health Records (EHRs). However, their implementation in…

Computation and Language · Computer Science 2026-01-12 Dongchen Li , Jitao Liang , Wei Li , Xiaoyu Wang , Longbing Cao , Kun Yu

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

The validity of AI safety evaluations depends on models behaving consistently across controlled and deployment settings. Prior work has identified test-time contextual cues, such as hypothetical scenarios, as a source of verbalized…

Computation and Language · Computer Science 2026-05-28 Katharina Deckenbach , Haritz Puerto , Jonas Geiping , Sahar Abdelnabi

Interpretable-by-design models are crucial for fostering trust, accountability, and safe adoption of automated decision-making models in real-world applications. In this paper we formalize the ground for the MIMOSA (Mining Interpretable…

Artificial Intelligence · Computer Science 2025-11-03 Riccardo Guidotti , Martina Cinquini , Marta Marchiori Manerba , Mattia Setzu , Francesco Spinnato

The U.S. Food and Drug Administration (FDA) released a landmark draft guidance in January 2026 on the use of Bayesian methodology to support primary inference in clinical trials of drugs and biological products. For sponsors, the central…

Applications · Statistics 2026-01-22 Yuan Ji , Ph. D