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Explanation methods and their evaluation have become a significant issue in explainable artificial intelligence (XAI) due to the recent surge of opaque AI models in decision support systems (DSS). Since the most accurate AI models are…

Artificial Intelligence · Computer Science 2023-08-30 Helena Löfström , Karl Hammar , Ulf Johansson

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these…

Human-Computer Interaction · Computer Science 2025-01-29 Olya Rezaeian , Alparslan Emrah Bayrak , Onur Asan

Gene set analysis (GSA) is a foundational approach for interpreting genomic data of diseases by linking genes to biological processes. However, conventional GSA methods overlook clinical context of the analyses, often generating long lists…

Providing high quality explanations for AI predictions based on machine learning is a challenging and complex task. To work well it requires, among other factors: selecting a proper level of generality/specificity of the explanation;…

We present a neurosymbolic approach, i.e., combining symbolic and subsymbolic artificial intelligence, to validating offer documents in regulated public institutions. We employ a language model to extract information and then aggregate with…

Artificial Intelligence · Computer Science 2026-04-08 Cedric Haufe , Frieder Stolzenburg

Large language models offer transformative potential for healthcare, yet their responsible and equitable development depends critically on a deeper understanding of how training data characteristics influence model behavior, including the…

Automated clinical decision support for clear aligner orthodontics faces a key challenge: bridging geometric perception (3D tooth segmentation) with clinical reasoning (biomechanical feasibility). We address this with OrthOAI, introducing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Edouard Lansiaux , Margaux Leman , Mehdi Ammi

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Current approaches to AI safety define red lines at the case level: specific prompts, specific outputs, specific harms. This paper argues that red lines can be set more fundamentally -- at the level of value, evidence, and source…

Artificial Intelligence · Computer Science 2026-04-14 Seulki Lee

Most existing approaches to AI in pharmacy collapse three epistemologically distinct operations into a single technical layer: document preservation, semantic interpretation, and contextual presentation. This conflation is a root cause of…

Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…

Artificial Intelligence · Computer Science 2026-01-21 Dipayan Sengupta , Saumya Panda

Recent advances in large language models (LLMs) have enabled their integration into clinical decision-making; however, hidden biases against patients across racial, social, economic, and clinical backgrounds persist. In this study, we…

Artificial Intelligence · Computer Science 2026-01-23 Ethan Zhang

As cannabis use has increased in recent years, researchers have come to rely on sophisticated machine learning models to predict cannabis use behavior and its impact on health. However, many artificial intelligence (AI) models lack…

Human-Computer Interaction · Computer Science 2025-03-11 Tongze Zhang , Tammy Chung , Anind Dey , Sang Won Bae

With the growing prevalence of machine learning and artificial intelligence-based medical decision support systems, it is equally important to ensure that these systems provide patient outcomes in a fair and equitable fashion. This paper…

Machine Learning · Statistics 2024-10-30 Jeffrey Smith , Andre Holder , Rishikesan Kamaleswaran , Yao Xie

The translation of artificial intelligence (AI) systems into clinical practice requires bridging fundamental gaps between explainable AI theory, clinician expectations, and governance requirements. While conceptual frameworks define what…

Computers and Society · Computer Science 2025-11-05 Alexander Bakumenko , Aaron J. Masino , Janine Hoelscher

Current AI systems rely on opaque reasoning processes that hinder human oversight and collaborative potential. Conventional explainable AI approaches offer post-hoc justifications and often fail to establish genuine symbiotic collaboration.…

Artificial Intelligence · Computer Science 2025-07-30 Jan Kapusta

Large language models (LLMs) are increasingly deployed in clinical decision support, yet subtle demographic cues can influence their reasoning. Prior work has documented disparities in outputs across patient groups, but little is known…

Computation and Language · Computer Science 2025-10-16 Rajarshi Ghosh , Abhay Gupta , Hudson McBride , Anurag Vaidya , Faisal Mahmood

Medicine and deep learning-based artificial intelligence (AI) engineering represent two distinct fields each with decades of published history. With such history comes a set of terminology that has a specific way in which it is applied.…