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Medical decision-support and advising systems are critical for emergency physicians to quickly and accurately assess patients' conditions and make diagnosis. Artificial Intelligence (AI) has emerged as a transformative force in healthcare…

Many automated labeling pipelines classify inputs into categories defined by a written specification, content moderation being a prominent use case. Simple category definitions are not detailed enough for labelers to produce the accurate,…

Computation and Language · Computer Science 2026-05-26 Konstantin Berlin , Adam Swanda

Generative medical AI now appears fluent and knowledgeable enough to resemble clinical intelligence, encouraging the belief that scaling will make it safe. But clinical reasoning is not text generation. It is a responsibility-bound process…

Artificial Intelligence · Computer Science 2026-02-02 Vaibhav Ram S. V. N. S , Swetanshu Agrawal , Samudra Banerjee , Abdul Muhsin

A decade of rapid advances in artificial intelligence (AI) has opened new opportunities for clinical decision support systems (CDSS), with large language models (LLMs) demonstrating strong reasoning abilities on timely medical tasks.…

Computation and Language · Computer Science 2025-11-25 Heejoon Koo

Large language model (LLM)-based AI agents are increasingly capable of complex clinical reasoning and may soon participate in medical decision-making with limited or no real-time human oversight. This shift raises fundamental questions…

Computers and Society · Computer Science 2026-03-17 Tom Bisson , Henriette Voelker , Sanddhya Jayabalan , A John Iafrate , Jakob N Kather , Jochen K Lennerz

Effective clinical decision-making depends on iterative, multimodal reasoning across diverse sources of evidence. The recent emergence of multimodal reasoning models has significantly transformed the landscape of solving complex tasks.…

Computation and Language · Computer Science 2025-11-04 Zhongzhen Huang , Linjie Mu , Yakun Zhu , Xiangyu Zhao , Shaoting Zhang , Xiaofan Zhang

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework provides a rigorous foundation for evidence synthesis, yet the manual processes of data extraction and literature screening remain time-consuming and…

Digital Libraries · Computer Science 2026-03-23 Samar Shailendra , Rajan Kadel , Aakanksha Sharma , Islam Mohammad Tahidul , Urvashi Rahul Saxena

The clinical adoption of biomedical vision-language models is hindered by prompt optimization techniques that produce either uninterpretable latent vectors or single textual prompts. This lack of transparency and failure to capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Kaushitha Silva , Mansitha Eashwara , Sanduni Ubayasiri , Ruwan Tennakoon , Damayanthi Herath

In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

Methodology · Statistics 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant…

Reliable and interpretable decision-making is essential in medical imaging, where diagnostic outcomes directly influence patient care. Despite advances in deep learning, most medical AI systems operate as opaque black boxes, providing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Pirzada Suhail , Aditya Anand , Amit Sethi

Language models often achieve higher accuracy when reasoning step-by-step in complex tasks. However, even when arriving at a correct final answer, their rationales are often logically unsound or inconsistent. This is a major issue when…

Artificial Intelligence · Computer Science 2023-11-09 Gabriel Poesia , Kanishk Gandhi , Eric Zelikman , Noah D. Goodman

Verification of biomedical claims is critical for healthcare decision-making, public health policy and scientific research. We present an interactive biomedical claim verification system by integrating LLMs, transparent model explanations,…

Human-Computer Interaction · Computer Science 2025-03-03 Siting Liang , Daniel Sonntag

Regulatory frameworks for the use of AI are emerging. However, they trail behind the fast-evolving malicious AI technologies that can quickly cause lasting societal damage. In response, we introduce a pioneering Assistive AI framework…

Designing sustainable medical devices requires balancing environmental, economic, and social demands, yet trade-offs across these pillars are difficult to identify using manual assessment alone. Current methods depend heavily on expert…

Physics and Society · Physics 2025-12-16 Apala Chakrabarti

Explainability in AI and ML models is critical for fostering trust, ensuring accountability, and enabling informed decision making in high stakes domains. Yet this objective is often unmet in practice. This paper proposes a general purpose…

Statistical Finance · Quantitative Finance 2025-09-03 N. Jean , G. Le Pera

Large language models with reasoning capabilities have demonstrated impressive performance across a wide range of domains. In clinical applications, a transparent, step-by-step reasoning process provides physicians with strong evidence to…

Artificial Intelligence · Computer Science 2025-12-16 Linjie Mu , Yannian Gu , Zhongzhen Huang , Yakun Zhu , Shaoting Zhang , Xiaofan Zhang

Clinical decision support systems (CDSS) augmented with artificial intelligence (AI) models are emerging as potentially valuable tools in healthcare. Despite their promise, the development and implementation of these systems typically…

Human-Computer Interaction · Computer Science 2023-03-08 Grace Golden , Christina Popescu , Sonia Israel , Kelly Perlman , Caitrin Armstrong , Robert Fratila , Myriam Tanguay-Sela , David Benrimoh

The composition of pre-training datasets for large language models (LLMs) remains largely undisclosed, hindering transparency and efforts to optimize data quality, a critical driver of model performance. Current data selection methods, such…

Computation and Language · Computer Science 2025-08-07 Xinlin Zhuang , Jiahui Peng , Ren Ma , Yinfan Wang , Tianyi Bai , Xingjian Wei , Jiantao Qiu , Chi Zhang , Ying Qian , Conghui He
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