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Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

Machine Learning · Computer Science 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole

Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting…

Machine Learning · Computer Science 2026-04-24 Weizhi Nie , Zhen Qu , Weijie Wang , Chunpei Li , Ke Lu , Bingyang Zhou , Hongzhi Yu

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

Many, if not most, systems of interest in science are naturally described as nonlinear dynamical systems. Empirically, we commonly access these systems through time series measurements. Often such time series may consist of discrete random…

Machine Learning · Computer Science 2024-06-10 Manuel Brenner , Florian Hess , Georgia Koppe , Daniel Durstewitz

Accurate mortality prediction allows Intensive Care Units (ICUs) to adequately benchmark clinical practice and identify patients with unexpected outcomes. Traditionally, simple statistical models have been used to assess patient death risk,…

Machine Learning · Computer Science 2020-05-20 William Caicedo-Torres , Jairo Gutierrez

Multimodal physiological data powers clinical AI systems from intensive care units to wearable devices, but sensors routinely fail in practice. Two failure modes are common: modality missing, where an entire channel is absent, and…

Machine Learning · Computer Science 2026-05-18 Wugeng Zheng , Ziwen Kan , Tianlong Chen , Chen Chen , Song Wang

Multi-modal medical imaging enables comprehensive diagnostics, yet current foundation models process 2D (e.g. X-ray) and 3D (e.g. CT) data with separate, dimensionality-specific architectures. We present MultiMedVision, a unified framework…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Frank Li , Bardia Khosravi , Mohammadreza Chavoshi , Young Seok Jeon , Theo Dapamede , Hari Trivedi , Janice Newsome , Judy Gichoya

Missing values, irregularly collected samples, and multi-resolution signals commonly occur in multivariate time series data, making predictive tasks difficult. These challenges are especially prevalent in the healthcare domain, where…

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

Machine Learning · Computer Science 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Clinical time series data from electronic health records and medical registries offer unprecedented opportunities to understand patient trajectories and inform medical decision-making. However, leveraging such data presents significant…

Machine Learning · Computer Science 2025-11-21 Muhammad Aslanimoghanloo , Ahmed ElGazzar , Marcel van Gerven

Multimodal learning seeks to combine data from multiple input sources to enhance the performance of different downstream tasks. In real-world scenarios, performance can degrade substantially if some input modalities are missing. Existing…

Machine Learning · Computer Science 2024-10-10 Niki Nezakati , Md Kaykobad Reza , Ameya Patil , Mashhour Solh , M. Salman Asif

Sleep abnormalities can have severe health consequences. Automated sleep staging, i.e. labelling the sequence of sleep stages from the patient's physiological recordings, could simplify the diagnostic process. Previous work on automated…

Signal Processing · Electrical Eng. & Systems 2023-04-14 Konstantinos Kontras , Christos Chatzichristos , Huy Phan , Johan Suykens , Maarten De Vos

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

Machine Learning · Computer Science 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Objective: To transform heterogeneous clinical data from electronic health records into clinically meaningful constructed features using data driven method that rely, in part, on temporal relations among data. Materials and Methods: The…

Machine Learning · Computer Science 2017-06-22 Edward Choi , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Substantial advances in multi-modal Artificial Intelligence (AI) facilitate the combination of diverse medical modalities to achieve holistic health assessments. We present COMPRER , a novel multi-modal, multi-objective pretraining…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Guy Lutsker , Hagai Rossman , Nastya Godiva , Eran Segal

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

Machine Learning · Computer Science 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang

Progress notes are among the most clinically meaningful artifacts in an Electronic Health Record (EHR), offering temporally grounded insights into a patient's evolving condition, treatments, and care decisions. Despite their importance,…

Computation and Language · Computer Science 2025-07-21 Garapati Keerthana , Manik Gupta

Integration of data from multiple omics techniques is becoming increasingly important in biomedical research. Due to non-uniformity and technical limitations in omics platforms, such integrative analyses on multiple omics, which we refer to…

Machine Learning · Computer Science 2021-02-11 Changhee Lee , Mihaela van der Schaar
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