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Missing data is a major challenge in clinical research. In electronic medical records, often a large fraction of the values in laboratory tests and vital signs are missing. The missingness can lead to biased estimates and limit our ability…

Machine Learning · Computer Science 2023-04-18 Omer Noy , Ron Shamir

Learning multimodal representations from medical images and other data sources can provide richer information for decision-making. While various multimodal models have been developed for this, they overlook learning features that are both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Boyu Chen , Weiye Bao , Junjie Liu , Michael Shen , Bo Peng , Paul Taylor , Zhu Li , Mengyue Yang

Objective: Clinical notes contain information not present elsewhere, including drug response and symptoms, all of which are highly important when predicting key outcomes in acute care patients. We propose the automatic annotation of…

Computation and Language · Computer Science 2021-11-25 Jingqing Zhang , Luis Bolanos , Ashwani Tanwar , Julia Ive , Vibhor Gupta , Yike Guo

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

Computers and Society · Computer Science 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

Clinical notes in electronic health records contain highly heterogeneous writing styles, including non-standard terminology or abbreviations. Using these notes in predictive modeling has traditionally required preprocessing (e.g. taking…

Machine Learning · Computer Science 2019-11-18 Jonas Kemp , Alvin Rajkomar , Andrew M. Dai

When training clinical prediction models from electronic health records (EHRs), a key concern should be a model's ability to sustain performance over time when deployed, even as care practices, database systems, and population demographics…

In hospitals, data are siloed to specific information systems that make the same information available under different modalities such as the different medical imaging exams the patient undergoes (CT scans, MRI, PET, Ultrasound, etc.) and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Tristan Sylvain , Francis Dutil , Tess Berthier , Lisa Di Jorio , Margaux Luck , Devon Hjelm , Yoshua Bengio

Real-world clinical time series data sets exhibit a high prevalence of missing values. Hence, there is an increasing interest in missing data imputation. Traditional statistical approaches impose constraints on the data-generating process…

Machine Learning · Computer Science 2020-01-13 Yang Guo , Zhengyuan Liu , Pavitra Krishnswamy , Savitha Ramasamy

The early prediction of sepsis in intensive care unit (ICU) patients is crucial for improving survival rates. However, the development of accurate predictive models is hampered by data fragmentation across healthcare institutions and the…

Machine Learning · Computer Science 2026-03-18 Yue Chang , Guangsen Lin , Jyun Jie Chuang , Shunqi Liu , Xinkui Li , Yaozheng Li

To study neurodegenerative diseases, longitudinal studies are carried on volunteer patients. During a time span of several months to several years, they go through regular medical visits to acquire data from different modalities, such as…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Cecilia Ostertag , Marie Beurton-Aimar , Muriel Visani , Thierry Urruty , Karell Bertet

A large fraction of the electronic health records (EHRs) consists of clinical measurements collected over time, such as lab tests and vital signs, which provide important information about a patient's health status. These sequences of…

Machine Learning · Statistics 2020-03-02 Karl Øyvind Mikalsen , Cristina Soguero-Ruiz , Robert Jenssen

Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine…

Machine Learning · Statistics 2019-08-13 Hrayr Harutyunyan , Hrant Khachatrian , David C. Kale , Greg Ver Steeg , Aram Galstyan

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

Machine Learning · Computer Science 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Multi-modal fusion approaches aim to integrate information from different data sources. Unlike natural datasets, such as in audio-visual applications, where samples consist of "paired" modalities, data in healthcare is often collected…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Nasir Hayat , Krzysztof J. Geras , Farah E. Shamout

Automated medical report generation has demonstrated the potential to significantly reduce the workload associated with time-consuming medical reporting. Recent generative representation learning methods have shown promise in integrating…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shuchang Ye , Mingyuan Meng , Mingjian Li , Dagan Feng , Usman Naseem , Jinman Kim

For mental disorders, patients' underlying mental states are non-observed latent constructs which have to be inferred from observed multi-domain measurements such as diagnostic symptoms and patient functioning scores. Additionally,…

Machine Learning · Computer Science 2020-11-03 Yuan Chen , Donglin Zeng , Tianchen Xu , Yuanjia Wang

Multimodal machine learning, mimicking the human brain's ability to integrate various modalities has seen rapid growth. Most previous multimodal models are trained on perfectly paired multimodal input to reach optimal performance. In…

Machine Learning · Computer Science 2026-02-06 Ronghao Lin , Qiaolin He , Sijie Mai , Ying Zeng , Aolin Xiong , Li Huang , Yap-Peng Tan , Haifeng Hu

Sepsis is a serious, life-threatening condition. When treating sepsis, it is challenging to determine the correct amount of intravenous fluids and vasopressors for a given patient. While automated reinforcement learning (RL)-based methods…

Machine Learning · Computer Science 2025-09-04 Taisiya Khakharova , Lucas Sakizloglou , Leen Lambers