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Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht

During the diagnostic process, clinicians leverage multimodal information, such as chief complaints, medical images, and laboratory-test results. Deep-learning models for aiding diagnosis have yet to meet this requirement. Here we report a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Hong-Yu Zhou , Yizhou Yu , Chengdi Wang , Shu Zhang , Yuanxu Gao , Jia Pan , Jun Shao , Guangming Lu , Kang Zhang , Weimin Li

Informative missingness is unavoidable in the digital processing of continuous time series, where the value for one or more observations at different time points are missing. Such missing observations are one of the major limitations of…

Machine Learning · Computer Science 2020-05-22 Mansura Habiba , Barak A. Pearlmutter

Effective modeling of electronic health records presents many challenges as they contain large amounts of irregularity most of which are due to the varying procedures and diagnosis a patient may have. Despite the recent progress in machine…

Machine Learning · Computer Science 2019-10-07 Sajad Darabi , Mohammad Kachuee , Majid Sarrafzadeh

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Privacy preservation in AI is crucial, especially in healthcare, where models rely on sensitive patient data. In the emerging field of machine unlearning, existing methodologies struggle to remove patient data from trained multimodal…

Machine Learning · Computer Science 2025-07-01 Shahad Hardan , Darya Taratynova , Abdelmajid Essofi , Karthik Nandakumar , Mohammad Yaqub

Predicting patient mortality is an important and challenging problem in the healthcare domain, especially for intensive care unit (ICU) patients. Electronic health notes serve as a rich source for learning patient representations, that can…

Computation and Language · Computer Science 2019-10-16 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

Computation and Language · Computer Science 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

Missing data is a persistent challenge in federated learning on electronic health records, particularly when institutions collect time-series data at varying temporal granularities. To address this, we propose Federated Markov Imputation…

Machine Learning · Computer Science 2025-09-26 Christoph Düsing , Philipp Cimiano

This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…

Machine Learning · Computer Science 2025-02-05 Linglong Qian , Yiyuan Yang , Wenjie Du , Jun Wang , Richard Dobsoni , Zina Ibrahim

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Real-time decoding of target variables from multiple simultaneously recorded neural time-series modalities, such as discrete spiking activity and continuous field potentials, is important across various neuroscience applications. However, a…

Machine Learning · Computer Science 2025-12-16 Eray Erturk , Maryam M. Shanechi

We have three contributions in this work: 1. We explore the utility of a stacked denoising autoencoder and a paragraph vector model to learn task-independent dense patient representations directly from clinical notes. To analyze if these…

Computation and Language · Computer Science 2018-07-05 Madhumita Sushil , Simon Šuster , Kim Luyckx , Walter Daelemans

A patient undergoes multiple examinations in each hospital stay, where each provides different facets of the health status. These assessments include temporal data with varying sampling rates, discrete single-point measurements, therapeutic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Malte Tölle , Mohamad Scharaf , Samantha Fischer , Christoph Reich , Silav Zeid , Christoph Dieterich , Benjamin Meder , Norbert Frey , Philipp Wild , Sandy Engelhardt

The healthcare domain is characterized by heterogeneous data modalities, such as imaging and physiological data. In practice, the variety of medical data assists clinicians in decision-making. However, most of the current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Nasir Hayat , Krzysztof J. Geras , Farah E. Shamout

Multimodal deep learning holds promise for improving clinical prediction by integrating diverse patient data, including text, imaging, time-series, and structured demographics. Contrastive learning facilitates this integration by producing…

Machine Learning · Computer Science 2025-07-08 Michal Golovanevsky , Pranav Mahableshwarkar , Carsten Eickhoff , Ritambhara Singh

Clinician burnout poses a substantial threat to patient safety, particularly in high-acuity intensive care units (ICUs). Existing research predominantly relies on retrospective survey tools or broad electronic health record (EHR) metadata,…

Computation and Language · Computer Science 2025-09-08 Syed Ahmad Chan Bukhari , Fazel Keshtkar , Alyssa Meczkowska

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Foundation models trained on electronic health records show strong performance on many clinical prediction tasks but are limited by sparse and irregular documentation. Wearable devices provide dense continuous physiological signals but lack…

Machine Learning · Computer Science 2026-01-21 Yuanyun Zhang , Han Zhou , Li Feng , Yilin Hong , Shi Li

Intensive Care Unit Electronic Health Records (ICU EHRs) store multimodal data about patients including clinical notes, sparse and irregularly sampled physiological time series, lab results, and more. To date, most methods designed to learn…

Machine Learning · Computer Science 2021-03-22 Satya Narayan Shukla , Benjamin M. Marlin
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