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Cervical cancer remains a significant health problem, especially in developing countries. Early detection is critical for effective treatment. Convolutional neural networks (CNN) have shown promise in automated cervical cancer screening,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Ach Khozaimi , Isnani Darti , Syaiful Anam , Wuryansari Muharini Kusumawinahyu

The Epithelial Dysplasia (ED) is a tissue alteration commonly present in lesions preceding oral cancer, being its presence one of the most important factors in the progression toward carcinoma. This study proposes a method to design a low…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Karoline da Rocha , José C. M. Bermudez , Elena R. C. Rivero , Márcio H. Costa

Recurrent spiking neural networks (RSNNs) hold great potential for advancing artificial general intelligence, as they draw inspiration from the biological nervous system and show promise in modeling complex dynamics. However, the…

Neural and Evolutionary Computing · Computer Science 2023-05-30 Guan Wang , Yuhao Sun , Sijie Cheng , Sen Song

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Evolutionary Computation is a group of biologically inspired algorithms used to solve complex optimisation problems. It can be split into Evolutionary Algorithms, which take inspiration from genetic inheritance, and Swarm Intelligence…

Neural and Evolutionary Computing · Computer Science 2021-08-11 Sizhe Yuen , Thomas H. G. Ezard , Adam J. Sobey

Current deep learning-based models typically analyze medical images in either 2D or 3D albeit disregarding volumetric information or suffering sub-optimal performance due to the anisotropic resolution of MR data. Furthermore, providing an…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alex Ling Yu Hung , Haoxin Zheng , Kai Zhao , Kaifeng Pang , Demetri Terzopoulos , Kyunghyun Sung

One of many important features of the tumour microenvironment is that it is a place of active Darwinian selection where different tumour clones become adapted to the variety of ecological niches that make up the microenvironment. These…

Biological Physics · Physics 2019-06-07 Thierry Fredrich , Heiko Rieger , Roberto Chignola , Edoardo Milotti

Modern cancer -omics and pharmacological data hold great promise in precision cancer medicine for developing individualized patient treatments. However, high heterogeneity and noise in such data pose challenges for predicting the response…

Quantitative Methods · Quantitative Biology 2020-11-18 Xiao Li , Tiffany M. Tang , Xuewei Wang , Jean-Pierre A. Kocher , Bin Yu

The Euclid Space Telescope will provide deep imaging at optical and near-infrared wavelengths, along with slitless near-infrared spectroscopy, across ~15,000 sq deg of the sky. Euclid is expected to detect ~12 billion astronomical sources,…

Instrumentation and Methods for Astrophysics · Physics 2023-03-15 Euclid Collaboration , A. Humphrey , L. Bisigello , P. A. C. Cunha , M. Bolzonella , S. Fotopoulou , K. Caputi , C. Tortora , G. Zamorani , P. Papaderos , D. Vergani , J. Brinchmann , M. Moresco , A. Amara , N. Auricchio , M. Baldi , R. Bender , D. Bonino , E. Branchini , M. Brescia , S. Camera , V. Capobianco , C. Carbone , J. Carretero , F. J. Castander , M. Castellano , S. Cavuoti , A. Cimatti , R. Cledassou , G. Congedo , C. J. Conselice , L. Conversi , Y. Copin , L. Corcione , F. Courbin , M. Cropper , A. Da Silva , H. Degaudenzi , M. Douspis , F. Dubath , C. A. J. Duncan , X. Dupac , S. Dusini , S. Farrens , S. Ferriol , M. Frailis , E. Franceschi , M. Fumana , P. Gomez-Alvarez , S. Galeotta , B. Garilli , W. Gillard , B. Gillis , C. Giocoli , A. Grazian , F. Grupp , L. Guzzo , S. V. H. Haugan , W. Holmes , F. Hormuth , K. Jahnke , M. Kummel , S. Kermiche , A. Kiessling , M. Kilbinger , T. Kitching , R. Kohley , M. Kunz , H. Kurki-Suonio , S. Ligori , P. B. Lilje , I. Lloro , E. Maiorano , O. Mansutti , O. Marggraf , K. Markovic , F. Marulli , R. Massey , S. Maurogordato , H. J. McCracken , E. Medinaceli , M. Melchior , M. Meneghetti , E. Merlin , G. Meylan , L. Moscardini , E. Munari , R. Nakajima , S. M. Niemi , J. Nightingale , C. Padilla , S. Paltani , F. Pasian , K. Pedersen , V. Pettorino , S. Pires , M. Poncet , L. Popa , L. Pozzetti , F. Raison , A. Renzi , J. Rhodes , G. Riccio , E. Romelli , M. Roncarelli , E. Rossetti , R. Saglia , D. Sapone , B. Sartoris , R. Scaramella , P. Schneider , M. Scodeggio , A. Secroun , G. Seidel , C. Sirignano , G. Sirri , L. Stanco , P. Tallada-Crespi , D. Tavagnacco , A. N. Taylor , I. Tereno , R. Toledo-Moreo , F. Torradeflot , I. Tutusaus , L. Valenziano , T. Vassallo , Y. Wang , J. Weller , A. Zacchei , J. Zoubian , S. Andreon , S. Bardelli , A. Boucaud , R. Farinelli , J. Gracia-Carpio , D. Maino , N. Mauri , S. Mei , N. Morisset , F. Sureau , M. Tenti , A. Tramacere , E. Zucca , C. Baccigalupi , A. Balaguera-Antolinez , A. Biviano , A. Blanchard , S. Borgani , E. Bozzo , C. Burigana , R. Cabanac , A. Cappi , C. S. Carvalho , S. Casas , G. Castignani , C. Colodro-Conde , A. R. Cooray , J. Coupon , H. M. Courtois , O. Cucciati , S. Davini , G. De Lucia , H. Dole , J. A. Escartin , S. Escoffier , M. Fabricius , M. Farina , F. Finelli , K. Ganga , J. Garcia-Bellido , K. George , F. Giacomini , G. Gozaliasl , I. Hook , M. Huertas-Company , B. Joachimi , V. Kansal , A. Kashlinsky , E. Keihanen , C. C. Kirkpatrick , V. Lindholm , G. Mainetti , R. Maoli , S. Marcin , M. Martinelli , N. Martinet , M. Maturi , R. B. Metcalf , G. Morgante , A. A. Nucita , L. Patrizii , A. Peel , J. E. Pollack , V. Popa , C. Porciani , D. Potter , P. Reimberg , A. G. Sanchez , M. Schirmer , M. Schultheis , V. Scottez , E. Sefusatti , J. Stadel , R. Teyssier , C. Valieri , J. Valiviita , M. Viel , F. Calura , H. Hildebrandt

Motivation: PCR is more economical and quicker than Next Generation Sequencing for detecting target organisms, with primer design being a critical step. In epidemiology with rapidly mutating viruses, designing effective primers is…

Genomics · Quantitative Biology 2025-12-18 Hanyu Wang , Emmanuel K. Tsinda , Anthony J. Dunn , Francis Chikweto , Alain B. Zemkoho

Urothelial cell carcinoma (UCC) is the ninth most common cancer that accounts for 4.7% of all the new cancer cases globally. UCC development and progression are due to complex and stochastic genetic programmes. To study the cascades of…

Causal discovery is a structured prediction task that aims to predict causal relations among variables based on their data samples. Supervised Causal Learning (SCL) is an emerging paradigm in this field. Existing Deep Neural Network…

Machine Learning · Computer Science 2025-02-18 Jiaru Zhang , Rui Ding , Qiang Fu , Bojun Huang , Zizhen Deng , Yang Hua , Haibing Guan , Shi Han , Dongmei Zhang

Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…

Molecular Networks · Quantitative Biology 2026-05-26 Hasi Hays , William J. Richardson

We have developed a method to improve the doping computation efficiency, this method is based on first principles calculations and cluster expansion. First principles codes produce highly accurate total energies and optimized geometries for…

Materials Science · Physics 2017-03-02 Zongguo Wang , Xiaoyu Yang , Xushan Zhao , Ligen Wang , Juan Wang , Mingming Zhang , Jie Ren

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

This study proposes MCEMOL (Multi-Constrained Evolutionary Molecular Design Framework), a molecular optimization approach integrating rule-based evolution with molecular crossover. MCEMOL employs dual-layer evolution: optimizing…

Neural and Evolutionary Computing · Computer Science 2026-01-16 Shanxian Lin , Wei Xia , Yuichi Nagata , Haichuan Yang

With the development of deep learning, Neural Code Models (NCMs) such as CodeBERT and CodeLlama are widely used for code understanding tasks, including defect detection and code classification. However, recent studies have revealed that…

Software Engineering · Computer Science 2026-03-26 Tingxu Han , Wei Song , Weisong Sun , Hao Wu , Chunrong Fang , Yuan Xiao , Xiaofang Zhang , Zhenyu Chen , Yang Liu
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