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Next-generation sequencing (NGS) is a pivotal technique in genome sequencing due to its high throughput, rapid results, cost-effectiveness, and enhanced accuracy. Its significance extends across various domains, playing a crucial role in…

Genomics · Quantitative Biology 2025-04-28 Fathima Nuzla Ismail , Shanika Amarasoma

Although there is extensive literature on the application of artificial neural networks (NNs) in quality control (QC), to monitor the conformity of a process to quality specifications, at least five QC measurements are required, increasing…

Neural and Evolutionary Computing · Computer Science 2023-10-19 Rallou A. Chatzimichail , Aristides T. Hatjimihail

Next Generation Sequencing (NGS), a recently evolved technology, have served a lot in the research and development sector of our society. This novel approach is a newbie and has critical advantages over the traditional Capillary…

Genomics · Quantitative Biology 2020-05-01 Khalid Raza , Sabahuddin Ahmad

Wide-field, multi-band surveys now detect millions of unresolved sources in nearby galaxy clusters, yet separating globular clusters (GCs) from foreground stars and background galaxies remains challenging. Scalable, automated classification…

Generative models can serve as surrogates for some real data sources by creating synthetic training datasets, but in doing so they may transfer biases to downstream tasks. We focus on protecting quality and diversity when generating…

Computers and Society · Computer Science 2025-09-08 Allen Chang , Matthew C. Fontaine , Serena Booth , Maja J. Matarić , Stefanos Nikolaidis

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

Machine Learning · Computer Science 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

Deep Neural Networks (DNNs), with its promising performance, are being increasingly used in safety critical applications such as autonomous driving, cancer detection, and secure authentication. With growing importance in deep learning,…

Machine Learning · Computer Science 2019-11-19 Senthil Mani , Anush Sankaran , Srikanth Tamilselvam , Akshay Sethi

Neural networks are trained by minimizing a loss function that defines the discrepancy between the predicted model output and the target value. The selection of the loss function is crucial to achieve task-specific behaviour and highly…

Computer Vision and Pattern Recognition · Computer Science 2024-04-22 Shakhnaz Akhmedova , Nils Körber

Next-generation sequencing (NGS) to profile temporal changes in living systems is gaining more attention for deriving better insights into the underlying biological mechanisms compared to traditional static sequencing experiments.…

The advent of DNA and RNA sequencing has revolutionized the study of genomics and molecular biology. Next generation sequencing (NGS) technologies like Illumina, Ion Torrent, SOLiD sequencing etc. have brought about a quick and cheap way to…

Genomics · Quantitative Biology 2021-03-26 Yun Heo , Gowthami Manikandan , Anand Ramachandran , Deming Chen

Analyses of targeted genomic sequencing data from next-generation-sequencing (NGS) technologies typically involves mapping reads to a reference sequence or clustering reads. For a number of species a reference genome is not available so the…

Genomics · Quantitative Biology 2016-02-16 Raunaq Malhotra , Daniel Elleder , Le Bao , David R Hunter , Raj Acharya , Mary Poss

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

Realistic human-centric rendering plays a key role in both computer vision and computer graphics. Rapid progress has been made in the algorithm aspect over the years, yet existing human-centric rendering datasets and benchmarks are rather…

Advances in generative models increase the need for sample quality assessment. To do so, previous methods rely on a pre-trained feature extractor to embed the generated samples and real samples into a common space for comparison. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jingyi Xu , Hieu Le , Dimitris Samaras

Because of the decreasing cost and high digital resolution, next-generation sequencing (NGS) is expected to replace the traditional hybridization-based microarray technology. For genetics study, the first-step analysis of NGS data is often…

Applications · Statistics 2014-01-13 Zhigen Zhao , Wei Wang , Zhi Wei

Next Generation Sequencing (NGS) technologies generate large amounts of short read data for many different organisms. The fact that NGS reads are generally short makes it challenging to assemble the reads and reconstruct the original genome…

Genomics · Quantitative Biology 2015-04-07 Jie Ren , Kai Song , Minghua Deng , Gesine Reinert , Charles H. Cannon , Fengzhu Sun

Precision medicine aims for personalized prognosis and therapeutics by utilizing recent genome-scale high-throughput profiling techniques, including next-generation sequencing (NGS). However, translating NGS data faces several challenges.…

In the rapidly evolving domain of next generation sequencing and bioinformatics analysis, data generation is one aspect that is increasing at a concomitant rate. The burden associated with processing large amounts of sequencing data has…

Genomics · Quantitative Biology 2015-03-11 Matthew J. Wade , Thomas P. Curtis , Russell J. Davenport

In the fields of Experimental and Computational Aesthetics, numerous image datasets have been created over the last two decades. In the present work, we provide a comparative overview of twelve image datasets that include aesthetic ratings…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Ralf Bartho , Katja Thoemmes , Christoph Redies

Motivation: Despite significant advances in Third-Generation Sequencing (TGS) technologies, Next-Generation Sequencing (NGS) technologies remain dominant in the current sequencing market. This is due to the lower error rates and richer…

Information Theory · Computer Science 2023-04-04 Jia Wang , Yi Niu , Tianyi Xu , Mingming Ma , Dahua Gao , Guangming Shi
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