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Modern data often arises with multiple modalities. For example, covariates and a network are observed on the same subjects, and both contain useful information. Effectively integrating these modalities is important and challenging,…

Methodology · Statistics 2025-11-25 Tao Shen , Wanjie Wang

The innovation of next-generation sequencing (NGS) techniques has significantly reduced the price of genome sequencing, lowering barriers to future medical research; it is now feasible to apply genome sequencing to studies where it would…

Genomics · Quantitative Biology 2024-06-06 Arshmeet Kaur , Morteza Sarmadi

In many applications, Neural Nets (NNs) have classification performance on par or even exceeding human capacity. Moreover, it is likely that NNs leverage underlying features that might differ from those humans perceive to classify. Can we…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Haowen Guan , Xuan Zhao , Zishi Wang , Zhiyang Li , Julia Kempe

Batch effects represent a major confounder in genomic diagnostics. In copy number variant (CNV) detection from NGS, many algorithms compare read depth between test samples and a reference sample, assuming they are process-matched. When this…

Genomics · Quantitative Biology 2026-01-16 Austin Talbot , Yue Ke

The research community continues to seek increasingly more advanced synthetic data generators to reliably evaluate the strengths and limitations of machine learning methods. This work aims to increase the availability of datasets…

Machine Learning · Computer Science 2026-01-30 Joanna Komorniczak

Benefit from large-scale training datasets, deep Convolutional Neural Networks(CNNs) have achieved impressive results in face recognition(FR). However, tremendous scale of datasets inevitably lead to noisy data, which obviously reduce the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-27 Wei Hu , Yangyu Huang , Fan Zhang , Ruirui Li

In this study, we propose a machine learning-based method for noise reduction and disease-causing gene feature extraction in gene sequencing DeepSeqDenoise algorithm combines CNN and RNN to effectively remove the sequencing noise, and…

Machine Learning · Computer Science 2025-05-27 Weichen Si , Yihao Ou , Zhen Tian

Graph neural networks (GNNs) have witnessed an unprecedented proliferation in tackling several problems in computer vision, computer-aided diagnosis, and related fields. While prior studies have focused on boosting the model accuracy,…

Machine Learning · Computer Science 2021-09-07 Mohammed Amine Gharsallaoui , Islem Rekik

To coupe with the difficulties in the process of inspection and classification of defects in Printed Circuit Board (PCB), other researchers have proposed many methods. However, few of them published their dataset before, which hindered the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Weibo Huang , Peng Wei

Over the last decades, hand-crafted feature extractors have been used to encode image visual properties into feature vectors. Recently, data-driven feature learning approaches have been successfully explored as alternatives for producing…

Computer Vision and Pattern Recognition · Computer Science 2020-11-25 Érico M. Pereira , Ricardo da S. Torres , Jefersson A. dos Santos

Learning with noisy labels has gained increasing attention because the inevitable imperfect labels in real-world scenarios can substantially hurt the deep model performance. Recent studies tend to regard low-loss samples as clean ones and…

Machine Learning · Computer Science 2024-02-20 Huafeng Liu , Mengmeng Sheng , Zeren Sun , Yazhou Yao , Xian-Sheng Hua , Heng-Tao Shen

When completed, the PHANGS-HST project will provide a census of roughly 50,000 compact star clusters and associations, as well as human morphological classifications for roughly 20,000 of those objects. These large numbers motivated the…

Graph Neural Networks (GNNs) have achieved great success on a node classification task. Despite the broad interest in developing and evaluating GNNs, they have been assessed with limited benchmark datasets. As a result, the existing…

Machine Learning · Computer Science 2022-12-29 Seiji Maekawa , Koki Noda , Yuya Sasaki , Makoto Onizuka

Due to the over-emphasize of the quantity of data, the data quality has often been overlooked. However, not all training data points contribute equally to learning. In particular, if mislabeled, it might actively damage the performance of…

Machine Learning · Computer Science 2021-09-13 Vaibhav Pulastya , Gaurav Nuti , Yash Kumar Atri , Tanmoy Chakraborty

Imbalanced datasets are ubiquitous. Classification performance on imbalanced datasets is generally poor for the minority class as the classifier cannot learn decision boundaries well. However, in sensitive applications like fraud detection,…

Machine Learning · Computer Science 2019-10-25 Vishwa Karia , Wenhao Zhang , Arash Naeim , Ramin Ramezani

Graphs, comprising nodes and edges, visually depict relationships and structures, posing challenges in extracting high-level features due to their intricate connections. Multiple connections introduce complexities in discovering patterns,…

Machine Learning · Computer Science 2024-11-12 Masoud Kargar , Nasim Jelodari , Alireza Assadzadeh

There is no consensus in the field of synthetic data on concise metrics for quality evaluations or benchmarks on large health datasets, such as historical epidemiological data. This study presents an evaluation of seven recent models from…

Machine Learning · Computer Science 2026-04-20 Jean-Baptiste Escudié , Benjamin Barnes , Stefan Meisegeier , Klaus Kraywinkel , Fabian Prasser , Nils Körber

Next-generation sequencing (NGS) technologies allow new methodologies for alternative splicing (AS) analysis. Current computational methods for AS from NGS data are mainly focused on predicting splice site junctions or de novo assembly of…

Genomics · Quantitative Biology 2012-08-15 Stefano Beretta , Paola Bonizzoni , Gianluca Della Vedova , Raffaella Rizzi

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

Effective search methods are crucial for improving the performance of deep generative models at test time. In this paper, we introduce a novel test-time search method, Neural Genetic Search (NGS), which incorporates the evolutionary…

Neural and Evolutionary Computing · Computer Science 2025-06-18 Hyeonah Kim , Sanghyeok Choi , Jiwoo Son , Jinkyoo Park , Changhyun Kwon