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Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

In recent years, there has been a growing trend in accelerating computationally complex non-real-time beamforming algorithms in ultrasound imaging using deep learning models. However, due to the large size and complexity these…

Hardware Architecture · Computer Science 2025-09-04 Abdul Rahoof , Vivek Chaturvedi , Mahesh Raveendranatha Panicker , Muhammad Shafique

The utilization of a reverberant shear wave field in shear wave elastography has emerged as a promising technique for achieving robust shear wave speed (SWS) estimation. However, accurately measuring SWS within such a complex wave field…

Image and Video Processing · Electrical Eng. & Systems 2024-02-06 Hamidreza Asemani , Irteza Enan Kabir , Juvenal Ormachea , Marvin M Doyley , Jannick P Rolland , Kevin J Parker

Scanning ion conductance microscopy (SICM) can image the surface topography of specimens in ionic solutions without mechanical probe--sample contact. This unique capability is advantageous for imaging fragile biological samples but its…

Applied Physics · Physics 2019-12-25 Shinji Watanabe , Satoko Kitazawa , Linhao Sun , Noriyuki Kodera , Toshio Ando

Coherent optics has demonstrated significant potential as a viable solution for achieving 100 Gb/s and higher speeds in single-wavelength passive optical networks (PON). However, upstream burst-mode coherent detection is a major challenge…

Signal Processing · Electrical Eng. & Systems 2024-09-24 Yongxin Sun , Hexun Jiang , Yicheng Xu , Mengfan Fu , Yixiao Zhu , Lilin Yi , Weisheng Hu , Qunbi Zhuge

A proton irradiation site for silicon detectors has been developed and commissioned at the Bonn Isochronous Cyclotron. The accelerator provides 14 MeV proton beams of up to 1 $\mu$A at beam widths of a few mm to the setup. Devices Under…

Instrumentation and Detectors · Physics 2024-05-07 Pascal Wolf , Dennis Sauerland , Reinhard Beck , Jochen Dingfelder

Purpose: In this study, procedures were developed to achieve efficient reversible conversion of a clinical linear accelerator (LINAC) and deliver electron FLASH (eFLASH) or conventional beams to the treatment room isocenter. Material &…

Atomic Beam Probe (ABP) is an extension of the routinely used Beam Emission Spectroscopy (BES) diagnostic for plasma edge current fluctuation measurement at magnetically confined plasmas. Beam atoms ionized by the plasma are directed to a…

A highly integrated, high performance, and re-configurable device, which is designed for the Nitrogen-Vacancy center based quantum applications, is reported. The digital compartment of the device is fully implemented in a…

Instrumentation and Detectors · Physics 2017-02-01 X. Qin , Z. Shi , Y. Xie , L. Wang , X. Rong , W. Jia , W. Zhang , J. Du

The Gaussian phase noise of intensity time series is demonstrated to be drastically reduced when the raw voltage data are digitally filtered through an arbitrarily large number $n$ of orthornormal bandpass profiles (eigen-filters) sharing…

Instrumentation and Methods for Astrophysics · Physics 2020-08-26 Richard Lieu , Kristen Lackeos

The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the development of a new generation of biosensors is diamond, due to its…

Instrumentation and Detectors · Physics 2016-08-30 F. Picollo , A. Battiato , E. Carbone , L. Croin , E. Enrico , J. Forneris , S. Gosso , P. Olivero , A. Pasquarelli , V. Carabelli

We present the development of the FBCM23 ASIC designed for the Phase-II upgrade of the Fast Beam Condition Monitoring (FBCM) system built at the CMS experiment which will replace the present luminometer based on the BCM1F ASIC [1]. The FBCM…

Signal Processing · Electrical Eng. & Systems 2024-02-29 Jan Kaplon , Grzegorz Wegrzyn , Konstantin Shibin , Marnix Barendregt

Within the ATTRACT FASTPIX project, a monolithic pixel sensor demonstrator chip has been developed in a modified 180 nm CMOS imaging process technology, targeting sub-nanosecond timing precision for single ionising particles. It features a…

We have commenced experiments with intense short pulses of ion beams on the Neutralized Drift Compression Experiment-II at Lawrence Berkeley National Laboratory, by generating beam spots size with radius r < 1 mm within 2 ns FWHM and…

We have recently performed experiments to test the effectiveness of three ion-clearing strategies in the Cornell high intensity photoinjector: DC clearing electrodes, bunch gaps, and beam shaking. The photoinjector reaches a new regime of…

Accelerator Physics · Physics 2016-04-20 Steven Full , Adam Bartnik , Ivan Bazarov , John Dobbins , Bruce Dunham , Georg Hoffstaetter

The investigation of coherent phenomena in strong-field processes requires interferometric measurement schemes with high selectivity to disentangle the complex nonlinear response of the system. Interferometers combining acousto-optical…

A whole class of two-color experiments involves intense, short Terahertz radiation pulses. A fast detector that is sensitive and able to resolve both near-infrared and Terahertz pulses at the same time is highly desirable. Here we present…

Optics · Physics 2013-08-14 S. Preu , M. Mittendorff , S. Winnerl , H. Lu , A. C. Gossard , H. B. Weber

Future strategic X-ray astronomy missions will require unprecedentedly sensitive wide-field imagers providing high frame rates, low readout noise and excellent soft energy response. To meet these needs, our team is employing a multi-pronged…

We report on the first detailed beam test attesting the fundamental principle behind the development of high-current-efficiency ultrafast electron microscope systems where a radio-frequency cavity is incorporated as a condenser lens in the…

Materials Science · Physics 2024-01-03 Xiaoyi Sun , Joseph William , Sachin Sharma , Shriraj Kunjir , Dan Morris , Shen Zhao , Chong-Yu Ruan

To perform precision medicine in realtime at home, a device capable of long distance continuously monitoring target biomolecules in unprocessed blood under dynamic situations is essential. In this study, an integrative buffer free wireless…