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The rapid growth of biomedical data, tools, and literature has created a fragmented research landscape that outpaces human expertise. While AI agents offer a solution, they typically rely on static, manually curated toolsets, limiting their…

Artificial Intelligence · Computer Science 2025-07-04 Ruofan Jin , Zaixi Zhang , Mengdi Wang , Le Cong

Large language model agents often fail to accumulate knowledge from experience, treating each task as an independent challenge. Recent methods extract experience as flattened textual knowledge, which cannot capture procedural logic of…

Artificial Intelligence · Computer Science 2026-02-02 Libin Qiu , Zhirong Gao , Junfu Chen , Yuhang Ye , Weizhi Huang , Xiaobo Xue , Wenkai Qiu , Shuo Tang

Artificial neural networks (ANN) have been shown to be flexible and effective function estimators for identification of nonlinear state-space models. However, if the resulting models are used directly for nonlinear model predictive control…

Systems and Control · Electrical Eng. & Systems 2023-04-03 Jan H. Hoekstra , Bence Cseppentő , Gerben I. Beintema , Maarten Schoukens , Zsolt Kollár , Roland Tóth

Integrating dynamical systems models with time series data is a central part of contemporary mathematical biology. With the rich variety of available models and data, numerous methods and computational tools have been developed for these…

Computation · Statistics 2026-03-24 Sara Hamis , John Forslund , Cici Chen Gu , Jodie A. Cochrane

Alignment research focuses on making individual AI systems reliable. Human institutions achieve reliable collective behaviour differently: they mitigate the risk posed by misaligned individuals through organisational structure. Multi-agent…

Artificial Intelligence · Computer Science 2026-02-17 William Waites

Table reasoning requires models to jointly perform comprehensive semantic understanding and precise numerical operations. Although recent large language model (LLM)-based methods have achieved promising results, most of them still rely on a…

Artificial Intelligence · Computer Science 2025-12-23 Chuang Jiang , Mingyue Cheng , Xiaoyu Tao , Qingyang Mao , Jie Ouyang , Qi Liu

Computer experiments are often performed to allow modeling of a response surface of a physical experiment that can be too costly or difficult to run except using a simulator. Running the experiment over a dense grid can be prohibitively…

Applications · Statistics 2009-05-25 Robert B. Gramacy , Herbert K. H. Lee

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Intelligent instruction-following robots capable of improving from autonomously collected experience have the potential to transform robot learning: instead of collecting costly teleoperated demonstration data, large-scale deployment of…

Robotics · Computer Science 2025-02-26 Zhiyuan Zhou , Pranav Atreya , Abraham Lee , Homer Walke , Oier Mees , Sergey Levine

Adapting production-level computer vision tools to bespoke scientific datasets is a critical "last mile" bottleneck. Current solutions are impractical: fine-tuning requires large annotated datasets scientists often lack, while manual code…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Xuefei , Wang , Kai A. Horstmann , Ethan Lin , Jonathan Chen , Alexander R. Farhang , Sophia Stiles , Atharva Sehgal , Jonathan Light , David Van Valen , Yisong Yue , Jennifer J. Sun

Automated fault diagnosis can facilitate diagnostics assistance, speedier troubleshooting, and better-organised logistics. Currently, AI-based prognostics and health management in the automotive industry ignore the textual descriptions of…

Computation and Language · Computer Science 2022-10-14 John Pavlopoulos , Alv Romell , Jacob Curman , Olof Steinert , Tony Lindgren , Markus Borg

Small language models are attractive for production deployment due to their low cost, fast inference, and ease of specialization. However, adapting them to a specific task remains a challenging engineering loop, driven not by training…

Artificial Intelligence · Computer Science 2026-04-14 Dhruv Atreja , Julia White , Nikhil Nayak , Kelton Zhang , Henrijs Princis , George Hurn-Maloney , Ash Lewis , Urchade Zaratiana

This work introduces an automated testing approach that employs agents controlling game characters to detect potential bugs within a game level. Harnessing the power of Bayesian Optimization (BO) to execute sample-efficient search, the…

Artificial Intelligence · Computer Science 2025-08-19 Carlos Celemin

AutoModel is an agent based architecture for the full lifecycle of industrial recommender systems. Instead of a fixed recall and ranking pipeline, AutoModel organizes recommendation as a set of interacting evolution agents with long term…

Information Retrieval · Computer Science 2026-04-10 Hao Zhang , Jinxin Hu , Hao Deng , Lingyu Mu , Shizhun Wang , Yu Zhang , Xiaoyi Zeng

Recent advances in large language models have sparked growing interest in AI agents capable of solving complex, real-world tasks. However, most existing agent systems rely on manually crafted configurations that remain static after…

Artificial Intelligence · Computer Science 2025-09-03 Jinyuan Fang , Yanwen Peng , Xi Zhang , Yingxu Wang , Xinhao Yi , Guibin Zhang , Yi Xu , Bin Wu , Siwei Liu , Zihao Li , Zhaochun Ren , Nikos Aletras , Xi Wang , Han Zhou , Zaiqiao Meng

Recently, using Large Language Models (LLMs) to generate optimization models from natural language descriptions has became increasingly popular. However, a major open question is how to validate that the generated models are correct and…

Artificial Intelligence · Computer Science 2026-04-07 Alexander Zadorojniy , Segev Wasserkrug , Eitan Farchi

We present AutoResearch-RL, a framework in which a reinforcement learning agent conducts open-ended neural architecture and hyperparameter research without human supervision, running perpetually until a termination oracle signals…

Machine Learning · Computer Science 2026-03-20 Nilesh Jain , Rohit Yadav , Sagar Kotian , Claude AI

Large language models (LLMs) excel in open domains but struggle in specialized settings with limited data and evolving knowledge. Existing domain adaptation practices rely heavily on manual trial-and-error processes, incur significant…

Machine Learning · Computer Science 2026-03-10 Sidharth Sinha , Anson Bastos , Xuchao Zhang , Akshay Nambi , Chetan Bansal , Saravan Rajmohan

The closed-loop performance of model predictive controllers (MPCs) is sensitive to the choice of prediction models, controller formulation, and tuning parameters. However, prediction models are typically optimized for prediction accuracy…

Systems and Control · Electrical Eng. & Systems 2020-11-25 Farshud Sorourifar , Georgios Makrygirgos , Ali Mesbah , Joel A. Paulson

Language agents have shown some ability to interact with an external environment, e.g., a virtual world such as ScienceWorld, to perform complex tasks, e.g., growing a plant, without the startup costs of reinforcement learning. However,…