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Survival outcome assessment is challenging and inherently associated with multiple clinical factors (e.g., imaging and genomics biomarkers) in cancer. Enabling multimodal analytics promises to reveal novel predictive patterns of patient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Kexin Ding , Mu Zhou , Dimitris N. Metaxas , Shaoting Zhang

Contrastive loss has been increasingly used in learning representations from multiple modalities. In the limit, the nature of the contrastive loss encourages modalities to exactly match each other in the latent space. Yet it remains an open…

Machine Learning · Computer Science 2023-03-13 Qian Jiang , Changyou Chen , Han Zhao , Liqun Chen , Qing Ping , Son Dinh Tran , Yi Xu , Belinda Zeng , Trishul Chilimbi

Missing data is a common problem in machine learning and in retrospective imaging research it is often encountered in the form of missing imaging modalities. We propose to take into account missing modalities in the design and training of…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Karin van Garderen , Marion Smits , Stefan Klein

Medical multi-modal learning is critical for integrating information from a large set of diverse modalities. However, when leveraging a high number of modalities in real clinical applications, it is often impractical to obtain full-modality…

Machine Learning · Computer Science 2026-03-03 Chenwei Wu , Zitao Shuai , Liyue Shen

Deep learning achieved great progress recently, however, it is not easy or efficient to further improve its performance by increasing the size of the model. Multi-modal learning can mitigate this challenge by introducing richer and more…

Artificial Intelligence · Computer Science 2025-10-07 Cairong Zhao , Yufeng Jin , Zifan Song , Haonan Chen , Duoqian Miao , Guosheng Hu

Multimodal sentiment analysis is an important research area that predicts speaker's sentiment tendency through features extracted from textual, visual and acoustic modalities. The central challenge is the fusion method of the multimodal…

Computation and Language · Computer Science 2020-09-29 Zilong Wang , Zhaohong Wan , Xiaojun Wan

Multimodal sentiment analysis relies on textual, acoustic, and visual signals, yet real-world data often suffer from modality missing and quality imbalance. Existing methods generate features for modality missing from available ones, but…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Chenglizhao Chen , Yuchen Cao , Xinyu Liu , Mengke Song , Guisheng Zhang , Xiaomin Yu

Survival prediction for esophageal squamous cell cancer (ESCC) is crucial for doctors to assess a patient's condition and tailor treatment plans. The application and development of multi-modal deep learning in this field have attracted…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Chengyu Wu , Yatao Zhang , Yaqi Wang , Qifeng Wang , Shuai Wang

Accurate survival prediction is essential for personalised cancer treatment. We propose ModalSurv, a multimodal deep survival framework integrating clinical, MRI, histopathology, and RNA-sequencing data via modality-specific projections and…

Machine Learning · Computer Science 2025-12-19 Noorul Wahab , Ethar Alzaid , Jiaqi Lv , Fayyaz Minhas , Adam Shephard , Shan E Ahmed Raza

Integrating multimodal datasets in clinical oncology is frequently hindered by high dimensionality and blockwise missingness, where entire data sources are unavailable for specific patient subsets. Standard survival models often struggle…

Liver cancer is one of the most common cancers worldwide. Due to inconspicuous texture changes of liver tumor, contrast-enhanced computed tomography (CT) imaging is effective for the diagnosis of liver cancer. In this paper, we focus on…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Yao Zhang , Jiawei Yang , Jiang Tian , Zhongchao Shi , Cheng Zhong , Yang Zhang , Zhiqiang He

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Zhaohu Xing , Sicheng Yang , Sixiang Chen , Tian Ye , Yijun Yang , Jing Qin , Lei Zhu

Survival analysis using whole-slide images (WSIs) is crucial in cancer research. Despite significant successes, pathology images typically only provide slide-level labels, which hinders the learning of discriminative representations from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Chengsheng Zhang , Linhao Qu , Xiaoyu Liu , Zhijian Song

Learning joint embedding space for various modalities is of vital importance for multimodal fusion. Mainstream modality fusion approaches fail to achieve this goal, leaving a modality gap which heavily affects cross-modal fusion. In this…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Sijie Mai , Haifeng Hu , Songlong Xing

This work focuses on learning useful and robust deep world models using multiple, possibly unreliable, sensors. We find that current methods do not sufficiently encourage a shared representation between modalities; this can cause poor…

Machine Learning · Computer Science 2021-07-07 Kaiqi Chen , Yong Lee , Harold Soh

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical…

Machine Learning · Computer Science 2026-01-21 Dianzhi Yu , Conghao Xiong , Yankai Chen , Wenqian Cui , Xinni Zhang , Yifei Zhang , Hao Chen , Joseph J. Y. Sung , Irwin King

Learning based on multimodal data has attracted increasing interest recently. While a variety of sensory modalities can be collected for training, not all of them are always available in development scenarios, which raises the challenge to…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shicai Wei , Yang Luo , Chunbo Luo

Multi-modal recommendation systems aim to enhance performance by integrating an item's content features across various modalities with user behavior data. Effective utilization of features from different modalities requires addressing two…

Information Retrieval · Computer Science 2025-02-27 Hang Zhou , Yucheng Wang , Huijing Zhan

Multimodal sentiment analysis is a core research area that studies speaker sentiment expressed from the language, visual, and acoustic modalities. The central challenge in multimodal learning involves inferring joint representations that…

Machine Learning · Computer Science 2020-03-02 Hai Pham , Paul Pu Liang , Thomas Manzini , Louis-Philippe Morency , Barnabas Poczos

Finding appropriate low dimensional representations of high-dimensional multi-modal data can be challenging, since each modality embodies unique deformations and interferences. In this paper, we address the problem using manifold learning,…

Signal Processing · Electrical Eng. & Systems 2018-08-23 Tal Shnitzer , Mirela Ben-Chen , Leonidas Guibas , Ronen Talmon , Hau-Tieng Wu