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Multimodal models often experience a significant performance drop when one or more modalities are missing during inference. To address this challenge, we propose a simple yet effective approach that enhances robustness to missing modalities…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Md Kaykobad Reza , Ameya Patil , Mashhour Solh , M. Salman Asif

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Diffusion models have emerged as powerful priors for solving inverse problems in computed tomography (CT). In certain applications, such as neutron CT, it can be expensive to collect large amounts of measurements even for a single scan,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Timofey Efimov , Singanallur Venkatakrishnan , Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

Cross-modality recognition has many important applications in science, law enforcement and entertainment. Popular methods to bridge the modality gap include reducing the distributional differences of representations of different modalities,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xin Niu , Enyi Li , Jinchao Liu , Yan Wang , Margarita Osadchy , Yongchun Fang

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, and genomic (e.g., bulk RNA-seq) for quantifying gene…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongxiao Wang , Yang Yang , Zhuo Zhao , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Standard multi-modal models assume the use of the same modalities in training and inference stages. However, in practice, the environment in which multi-modal models operate may not satisfy such assumption. As such, their performances…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Sangmin Woo , Sumin Lee , Yeonju Park , Muhammad Adi Nugroho , Changick Kim

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Accurately predicting the survival of cancer patients is crucial for personalized treatment. However, existing studies focus solely on the relationships between samples with known survival risks, without fully leveraging the value of…

Machine Learning · Computer Science 2025-07-23 Hailin Yue , Hulin Kuang , Jin Liu , Junjian Li , Lanlan Wang , Mengshen He , Jianxin Wang

We propose a new deep learning method for tumour segmentation when dealing with missing imaging modalities. Instead of producing one network for each possible subset of observed modalities or using arithmetic operations to combine feature…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Reuben Dorent , Samuel Joutard , Marc Modat , Sébastien Ourselin , Tom Vercauteren

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Accurate brain tumor segmentation using multiparametric MRI is critical for effective treatment planning. However, in clinical settings, complete acquisition of all MRI sequences is not always possible. The absence of certain MRI modalities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Danish Ali , Ajmal Mian , Naveed Akhtar , Ghulam Mubashar Hassan

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

Multi-modal learning relates information across observation modalities of the same physical phenomenon to leverage complementary information. Most multi-modal machine learning methods require that all the modalities used for training are…

Machine Learning · Computer Science 2021-03-10 Vandana Rajan , Alessio Brutti , Andrea Cavallaro

Combining images from multi-modalities is beneficial to explore various information in computer vision, especially in the medical domain. As an essential part of clinical diagnosis, multi-modal brain tumor segmentation aims to delineate the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Zhongzhen Huang , Linda Wei , Shaoting Zhang , Xiaofan Zhang

Multimodal MR images can provide complementary information for accurate brain tumor segmentation. However, it's common to have missing imaging modalities in clinical practice. Since there exists a strong correlation between multi…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Esophageal cancer is one of the most common types of cancer worldwide and ranks sixth in cancer-related mortality. Accurate computer-assisted diagnosis of cancer progression can help physicians effectively customize personalized treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Chengyu Wu , Chengkai Wang , Yaqi Wang , Huiyu Zhou , Yatao Zhang , Qifeng Wang , Shuai Wang

Accurate segmentation of brain tumors from magnetic resonance imaging (MRI) is clinically relevant in diagnoses, prognoses and surgery treatment, which requires multiple modalities to provide complementary morphological and physiopathologic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-30 Yixin Wang , Yang Zhang , Yang Liu , Zihao Lin , Jiang Tian , Cheng Zhong , Zhongchao Shi , Jianping Fan , Zhiqiang He