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We propose a new framework for zero-shot generation of synthetic tabular data. Using the large language model (LLM) GPT-4o and plain-language prompting, we demonstrate the ability to generate high-fidelity tabular data without task-specific…

Machine Learning · Computer Science 2025-02-21 Austin A. Barr , Robert Rozman , Eddie Guo

Access to large-scale high-quality healthcare databases is key to accelerate medical research and make insightful discoveries about diseases. However, access to such data is often limited by patient privacy concerns, data sharing…

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

Automatic detection of depression is a rapidly growing field of research at the intersection of psychology and machine learning. However, with its exponential interest comes a growing concern for data privacy and scarcity due to the…

Machine Learning · Computer Science 2024-11-27 Andrea Kang , Jun Yu Chen , Zoe Lee-Youngzie , Shuhao Fu

Synthetic tabular data generation with differential privacy is a crucial problem to enable data sharing with formal privacy. Despite a rich history of methodological research and development, developing differentially private tabular data…

Machine Learning · Computer Science 2024-06-05 Toan V. Tran , Li Xiong

Clinical data is fundamental to advance neurosurgical research, but access is often constrained by data availability, small sample sizes, privacy regulations, and resource-intensive preprocessing and de-identification procedures. Synthetic…

Computation and Language · Computer Science 2025-10-21 Austin A. Barr , Eddie Guo , Emre Sezgin

Large Language Models (LLMs) offer a flexible means to generate synthetic tabular data, yet existing approaches often fail to preserve key causal parameters such as the average treatment effect (ATE). In this technical exploration, we first…

Machine Learning · Computer Science 2025-11-04 Dana Kim , Yichen Xu , Tiffany Lin

Large Language Models (LLMs) are increasingly deployed in mental health contexts, from structured therapeutic support tools to informal chat-based well-being assistants. While these systems increase accessibility, scalability, and…

Human-Computer Interaction · Computer Science 2025-10-14 Soraya S. Anvari , Rina R. Wehbe

In the era of big data, access to abundant data is crucial for driving research forward. However, such data is often inaccessible due to privacy concerns or high costs, particularly in healthcare domain. Generating synthetic (tabular) data…

Machine Learning · Computer Science 2026-04-10 Yaobin Ling , Xiaoqian Jiang , Yejin Kim

Data serves as the fundamental foundation for advancing deep learning, particularly tabular data presented in a structured format, which is highly conducive to modeling. However, even in the era of LLM, obtaining tabular data from sensitive…

Machine Learning · Computer Science 2024-08-07 Yuxin Wang , Duanyu Feng , Yongfu Dai , Zhengyu Chen , Jimin Huang , Sophia Ananiadou , Qianqian Xie , Hao Wang

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…

Computation and Language · Computer Science 2024-03-15 Erlend Frayling , Jake Lever , Graham McDonald

In this study, we explore the growing potential of AI and deep learning technologies, particularly Generative Adversarial Networks (GANs) and Large Language Models (LLMs), for generating synthetic tabular data. Access to quality students…

Machine Learning · Computer Science 2026-05-21 Mohammad Khalil , Sam Urmian , Ronas Shakya , Qinyi Liu

Synthetic clinical data are increasingly important for advancing AI in healthcare, given strict privacy constraints on real-world EHRs, limited availability of annotated rare-condition data, and systemic biases in observational datasets.…

Machine Learning · Computer Science 2025-09-16 Rumeng Li , Xun Wang , Hong Yu

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

The development of AI for mental health is hindered by a lack of authentic therapy dialogues, due to strict privacy regulations and the fact that clinical sessions were historically rarely recorded. We present an LLM-driven pipeline that…

Suicidal ideation detection is a vital research area that holds great potential for improving mental health support systems. However, the sensitivity surrounding suicide-related data poses challenges in accessing large-scale, annotated…

Computation and Language · Computer Science 2024-02-06 Hamideh Ghanadian , Isar Nejadgholi , Hussein Al Osman

Synthetic tabular data are often evaluated by distributional similarity, privacy distance, or train-on-synthetic-test-on-real predictive performance, but these criteria do not ensure validity for causal inference. We show that fully…

Methodology · Statistics 2026-05-12 Yichen Xu

Access to real-world medical data is often restricted due to privacy regulations, posing a significant barrier to the advancement of healthcare research. Synthetic data offers a promising alternative; however, generating realistic,…

Artificial Intelligence · Computer Science 2025-08-13 Arshia Ilaty , Hossein Shirazi , Hajar Homayouni
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