English

Fidelity, Diversity, and Privacy: A Multi-Dimensional LLM Evaluation for Clinical Data Augmentation

Machine Learning 2026-05-01 v1 Cryptography and Security

Abstract

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a promising alternative. The use of Large Language Models (LLMs) in a data augmentation pipeline could be leveraged as an alternative in this field. In the proposed methodology, DeepSeek-R1, OpenBioLLM-Llama3 and Qwen 3.5 are used to generate synthetic mental health evaluation reports conditioned on specific International Classification of Diseases, Tenth Revision (ICD-10) codes. Because naive text generation can lead to mode collapse or privacy breaches (memorization), a comprehensive evaluation framework is introduced. The generated diagnostic texts are assessed across three dimensions: semantic fidelity, lexical diversity, and privacy/plagiarism. The results demonstrate that all models can generate clinically coherent, diverse, and privacy-safe synthetic reports, significantly expanding the available training data for clinical natural language processing tasks without compromising patient confidentiality.

Keywords

Cite

@article{arxiv.2604.27014,
  title  = {Fidelity, Diversity, and Privacy: A Multi-Dimensional LLM Evaluation for Clinical Data Augmentation},
  author = {Guillermo Iglesias and Gema Bello-Orgaz and María Navas-Loro and Cristian Ramirez-Atencia and Mercè Salvador Robert and Enrique Baca-Garcia},
  journal= {arXiv preprint arXiv:2604.27014},
  year   = {2026}
}

Comments

9 pages, 1 figure, 1 table

R2 v1 2026-07-01T12:42:03.878Z