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Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

Computation and Language · Computer Science 2024-02-27 Salman Rahman , Lavender Yao Jiang , Saadia Gabriel , Yindalon Aphinyanaphongs , Eric Karl Oermann , Rumi Chunara

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

Pre-training large-scale neural language models on raw texts has made a significant contribution to improving transfer learning in natural language processing (NLP). With the introduction of transformer-based language models, such as…

Computation and Language · Computer Science 2024-05-08 Shoya Wada , Toshihiro Takeda , Shiro Manabe , Shozo Konishi , Jun Kamohara , Yasushi Matsumura

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

The performance of deep learning-based natural language processing systems is based on large amounts of labeled training data which, in the clinical domain, are not easily available or affordable. Weak supervision and in-context learning…

Computation and Language · Computer Science 2025-04-02 Enshuo Hsu , Kirk Roberts

This study examines whether Low-Rank Adaptation (LoRA) fine-tuned Large Language Models (LLMs) can approximate the performance of fully fine-tuned models in generating human-interpretable decisions and explanations for malware…

Cryptography and Security · Computer Science 2025-11-26 Stephen C. Gravereaux , Sheikh Rabiul Islam

Background: Clinical natural language processing (NLP) refers to the use of computational methods for extracting, processing, and analyzing unstructured clinical text data, and holds a huge potential to transform healthcare in various…

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Large Language Models (LLMs) have the unique capability to understand and generate human-like text from input queries. When fine-tuned, these models show enhanced performance on domain-specific queries. OpenAI highlights the process of…

Computation and Language · Computer Science 2024-07-02 Scott Barnett , Zac Brannelly , Stefanus Kurniawan , Sheng Wong

The rapid expansion of electronic health record (EHR) systems has generated large volumes of unstructured clinical narratives that contain valuable information for disease identification, patient cohort discovery, and clinical decision…

Computation and Language · Computer Science 2026-03-17 Fariba Afrin Irany , Sampson Akwafuo

Large Language Models (LLM's) have demonstrated considerable success in various Natural Language Processing tasks, but they have yet to attain state-of-the-art performance in Neural Machine Translation (NMT). Nevertheless, their significant…

Computation and Language · Computer Science 2024-03-20 Sai Koneru , Miriam Exel , Matthias Huck , Jan Niehues

Deploying large language models (LLMs) for structured data extraction in domains such as financial compliance reporting, legal document analytics, and multilingual knowledge base construction is often impractical for smaller teams due to…

Computation and Language · Computer Science 2025-09-11 Yu Cheng Chih , Yong Hao Hou

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

In enterprise search, building high-quality datasets at scale remains a central challenge due to the difficulty of acquiring labeled data. To resolve this challenge, we propose an efficient approach to fine-tune small language models (SLMs)…

We introduce LLMD, a large language model designed to analyze a patient's medical history based on their medical records. Along with domain knowledge, LLMD is trained on a large corpus of records collected over time and across facilities,…

Large Language Models are traditionally finetuned on large instruction datasets. However recent studies suggest that small, high-quality datasets can suffice for general purpose instruction following. This lack of consensus surrounding…

Machine Learning · Computer Science 2023-12-29 Aditi Jha , Sam Havens , Jeremy Dohmann , Alex Trott , Jacob Portes
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