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Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

The advancement of natural language processing (NLP) systems in healthcare hinges on language model ability to interpret the intricate information contained within clinical notes. This process often requires integrating information from…

Computation and Language · Computer Science 2024-03-12 Zhichao Yang , Avijit Mitra , Sunjae Kwon , Hong Yu

Improving the accuracy and reliability of medical coding reduces clinician burnout and supports revenue cycle processes, freeing providers to focus more on patient care. However, automating the assignment of ICD-10-CM and CPT codes from…

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

Systematic reviews traditionally have taken considerable amounts of human time and energy to complete, in part due to the extensive number of titles and abstracts that must be reviewed for potential inclusion. Recently, researchers have…

Computation and Language · Computer Science 2026-03-27 Kweku Yamoah , Noah Schroeder , Emmanuel Dorley , Neha Rani , Caleb Schutz

Extracting structured medical insights from unstructured clinical text using Natural Language Processing (NLP) remains an open challenge in healthcare, particularly in non-English contexts where resources are scarce. This study presents a…

Artificial Intelligence · Computer Science 2025-11-21 Paulina Tworek , Miłosz Bargieł , Yousef Khan , Tomasz Pełech-Pilichowski , Marek Mikołajczyk , Roman Lewandowski , Jose Sousa

Medical reports contain rich clinical information but are often unstructured and written in domain-specific language, posing challenges for information extraction. While proprietary large language models (LLMs) have shown promise in…

Computation and Language · Computer Science 2026-03-12 Luc Builtjes , Joeran Bosma , Mathias Prokop , Bram van Ginneken , Alessa Hering

The biomedical domain has sparked a significant interest in the field of Natural Language Processing (NLP), which has seen substantial advancements with pre-trained language models (PLMs). However, comparing these models has proven…

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

In this study, we investigated the ability of the large language model (LLM) to enhance healthcare data interoperability. We leveraged the LLM to convert clinical texts into their corresponding FHIR resources. Our experiments, conducted on…

Computation and Language · Computer Science 2023-10-23 Yikuan Li , Hanyin Wang , Halid Yerebakan , Yoshihisa Shinagawa , Yuan Luo

Large language models (LLMs) have significantly advanced various natural language processing (NLP) tasks. Recent research indicates that moderately-sized LLMs often outperform larger ones after task-specific fine-tuning. This study focuses…

Computation and Language · Computer Science 2024-10-14 Minghao Wu , Thuy-Trang Vu , Lizhen Qu , George Foster , Gholamreza Haffari

Large Language Models (LLMs) recently achieved great success in medical text summarization by simply using in-context learning. However, these recent efforts do not perform fine-grained evaluations under difficult settings where LLMs might…

Computation and Language · Computer Science 2026-04-22 Gunjan Balde , Soumyadeep Roy , Mainack Mondal , Niloy Ganguly

Objective Structured Clinical Examinations (OSCEs) are the standard method for assessing medical students' clinical and communication skills through structured patient interviews. In France, however, the organization of training sessions is…

Computation and Language · Computer Science 2026-04-10 Tian Huang , Tom Bourgeade , Irina Illina

Legal reasoning tasks present unique challenges for large language models (LLMs) due to the complexity of domain-specific knowledge and reasoning processes. This paper investigates how effectively smaller language models (Llama 2 7B and…

Machine Learning · Computer Science 2025-04-08 Rean Fernandes , André Biedenkapp , Frank Hutter , Noor Awad

Generative Large Language Models (LLMs) have achieved remarkable advancements in various NLP tasks. However, these advances have not been reflected in the translation task, especially those with moderate model sizes (i.e., 7B or 13B…

Computation and Language · Computer Science 2024-02-07 Haoran Xu , Young Jin Kim , Amr Sharaf , Hany Hassan Awadalla

Pathology reports serve as the definitive record for breast cancer staging, yet their unstructured format impedes large-scale data curation. While Large Language Models (LLMs) offer semantic reasoning, their deployment is often limited by…

Machine Learning · Computer Science 2026-04-16 Jiahao Shao , Anam Nawaz Khan , Christopher Brett , Tom Berg , Xueping Li , Bing Yao

Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…

Computation and Language · Computer Science 2026-04-30 Pierre Epron , Adrien Coulet , Mehwish Alam

Large language models (LLMs) such as ChatGPT are fine-tuned on large and diverse instruction-following corpora, and can generalize to new tasks. However, those instruction-tuned LLMs often perform poorly in specialized medical natural…

Computation and Language · Computer Science 2025-03-11 Yujuan Velvin Fu , Giridhar Kaushik Ramachandran , Namu Park , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen
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