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The entry of large language models (LLMs) into research and commercial spaces has led to a trend of ever-larger models, with initial promises of generalisability, followed by a widespread desire to downsize and create specialised models…

Computation and Language · Computer Science 2024-02-19 Niall Taylor , Upamanyu Ghose , Omid Rohanian , Mohammadmahdi Nouriborji , Andrey Kormilitzin , David Clifton , Alejo Nevado-Holgado

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Low-resource languages (LRLs) lack sufficient linguistic resources and are underrepresented in benchmark datasets, resulting in persistently lower translation quality than high-resource languages, especially in privacy-sensitive and…

Computation and Language · Computer Science 2025-08-25 Yewei Song , Lujun Li , Cedric Lothritz , Saad Ezzini , Lama Sleem , Niccolo Gentile , Radu State , Tegawendé F. Bissyandé , Jacques Klein

Few-shot learning has been studied to adapt models to tasks with very few samples. It holds profound significance, particularly in clinical tasks, due to the high annotation cost of medical images. Several works have explored few-shot…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Kaipeng Zheng , Weiran Huang , Lichao Sun

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

Natural language processing (NLP) in the medical domain can underperform in real-world applications involving small datasets in a non-English language with few labeled samples and imbalanced classes. There is yet no consensus on how to…

Computation and Language · Computer Science 2024-10-01 Vincent Beliveau , Helene Kaas , Martin Prener , Claes N. Ladefoged , Desmond Elliott , Gitte M. Knudsen , Lars H. Pinborg , Melanie Ganz

In NLP classification tasks where little labeled data exists, domain fine-tuning of transformer models on unlabeled data is an established approach. In this paper we have two aims. (1) We describe our observations from fine-tuning the…

Computation and Language · Computer Science 2026-04-17 Rami Luisto , Liisa Petäinen , Tommi Grönholm , Jan Böhm , Maarit Ahtiainen , Tomi Lilja , Ilkka Pölönen , Sami Äyrämö

The recent success of Large Language Models (LLMs) has gained significant attention in both academia and industry. Substantial efforts have been made to enhance the zero- and few-shot generalization capabilities of open-source LLMs through…

Computation and Language · Computer Science 2023-10-03 Zongxi Li , Xianming Li , Yuzhang Liu , Haoran Xie , Jing Li , Fu-lee Wang , Qing Li , Xiaoqin Zhong

Large Language Models (LLMs) have demonstrated impressive capabilities across diverse Natural Language Processing (NLP) tasks, including language understanding, reasoning, and generation. However, general-domain LLMs often struggle with…

Computation and Language · Computer Science 2024-11-06 Sorouralsadat Fatemi , Yuheng Hu , Maryam Mousavi

Large language models (LLMs) show promise in drafting responses to patient portal messages, yet their integration into clinical workflows raises various concerns, including whether they would actually save clinicians time and effort in…

Computation and Language · Computer Science 2026-01-19 Parker Seegmiller , Joseph Gatto , Sarah E. Greer , Ganza Belise Isingizwe , Rohan Ray , Timothy E. Burdick , Sarah Masud Preum

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

Artificial Intelligence · Computer Science 2025-03-07 Hejie Cui , Alyssa Unell , Bowen Chen , Jason Alan Fries , Emily Alsentzer , Sanmi Koyejo , Nigam Shah

Large language models (LLMs) have excelled in various NLP tasks, including machine translation (MT), yet most studies focus on sentence-level translation. This work investigates the inherent capability of instruction-tuned LLMs for…

Computation and Language · Computer Science 2025-04-22 Yirong Sun , Dawei Zhu , Yanjun Chen , Erjia Xiao , Xinghao Chen , Xiaoyu Shen

The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Computation and Language · Computer Science 2025-12-19 Xunxin Cai , Chengrui Wang , Qingqing Long , Yuanchun Zhou , Meng Xiao

Grading Objective Structured Clinical Examinations (OSCEs) is a time-consuming and expensive process, traditionally requiring extensive manual effort from human experts. In this study, we explore the potential of Large Language Models…

Fine-tuning and testing a multilingual large language model is expensive and challenging for low-resource languages (LRLs). While previous studies have predicted the performance of natural language processing (NLP) tasks using machine…

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

Computers and Society · Computer Science 2024-05-15 Wen Wang , Zhenyue Zhao , Tianshu Sun

Radiology reports are critical for clinical decision-making but often lack a standardized format, limiting both human interpretability and machine learning (ML) applications. While large language models (LLMs) have shown strong capabilities…

Computation and Language · Computer Science 2025-07-15 Johannes Moll , Louisa Fay , Asfandyar Azhar , Sophie Ostmeier , Tim Lueth , Sergios Gatidis , Curtis Langlotz , Jean-Benoit Delbrouck

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Language Models (LMs) have performed well on biomedical natural language processing applications. In this study, we conducted some experiments to use prompt methods to extract knowledge from LMs as new knowledge Bases (LMs as KBs). However,…

Information Retrieval · Computer Science 2022-10-24 Zonghai Yao , Yi Cao , Zhichao Yang , Vijeta Deshpande , Hong Yu