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For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

There is growing interest in exploring user simulation as an alternative to gathering and scoring real user-chatbot interactions for AI chatbot evaluation. For this purpose, it is important to ensure the realism of the simulation, i.e., the…

Computation and Language · Computer Science 2026-05-05 Yu Lu Liu , Hyokun Yun , Tanya Roosta , Ziang Xiao

Large language models are increasingly deployed in multi-turn settings such as tutoring, support, and counseling, where reliability depends on preserving consistent roles, personas, and goals across long horizons. This requirement becomes…

Computation and Language · Computer Science 2026-04-13 Han Luo , Guy Laban

Synthetic data are becoming a critical tool for building artificially intelligent systems. Simulators provide a way of generating data systematically and at scale. These data can then be used either exclusively, or in conjunction with real…

Artificial Intelligence · Computer Science 2023-04-07 Daniel McDuff , Theodore Curran , Achuta Kadambi

The increasing demand for mental health services has highlighted the need for innovative solutions, particularly in the realm of psychological conversational AI, where the availability of sensitive data is scarce. In this work, we explored…

Human-Computer Interaction · Computer Science 2024-12-31 Alessandro De Grandi , Federico Ravenda , Andrea Raballo , Fabio Crestani

Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating…

Machine Learning · Computer Science 2019-11-28 Saloni Dash , Ritik Dutta , Isabelle Guyon , Adrien Pavao , Andrew Yale , Kristin P. Bennett

Recent efforts in Spoken Dialogue Modeling aim to synthesize spoken dialogue without the need for direct transcription, thereby preserving the wealth of non-textual information inherent in speech. However, this approach faces a challenge…

Computation and Language · Computer Science 2024-07-03 Yu-Kuan Fu , Cheng-Kuang Lee , Hsiu-Hsuan Wang , Hung-yi Lee

The rapid growth in data availability has facilitated research and development, yet not all industries have benefited equally due to legal and privacy constraints. The healthcare sector faces significant challenges in utilizing patient data…

Methodology · Statistics 2025-11-18 Katariina Perkonoja , Kari Auranen , Joni Virta

Clinical information extraction, which involves structuring clinical concepts from unstructured medical text, remains a challenging problem that could benefit from the inclusion of tabular background information available in electronic…

Artificial Intelligence · Computer Science 2025-12-10 Paloma Rabaey , Stefan Heytens , Thomas Demeester

Modeling & Simulation (M&S) approaches such as agent-based models hold significant potential to support decision-making activities in health, with recent examples including the adoption of vaccines, and a vast literature on healthy eating…

Artificial Intelligence · Computer Science 2025-09-08 Philippe J. Giabbanelli , Ameeta Agrawal

Recent advances in large language models (LLMs) have accelerated the development of conversational agents capable of generating human-like responses. Since psychiatric assessments typically involve complex conversational interactions…

Computation and Language · Computer Science 2025-01-06 Jingoo Lee , Kyungho Lim , Young-Chul Jung , Byung-Hoon Kim

Simulating human profiles by instilling personas into large language models (LLMs) is rapidly transforming research in agentic behavioral simulation, LLM personalization, and human-AI alignment. However, most existing synthetic personas…

Artificial Intelligence · Computer Science 2025-12-02 Zhen Wang , Yufan Zhou , Zhongyan Luo , Lyumanshan Ye , Adam Wood , Man Yao , Saab Mansour , Luoshang Pan

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

User simulators are crucial for replicating human interactions with dialogue systems, supporting both collaborative training and automatic evaluation, especially for large language models (LLMs). However, current role-playing methods face…

Computation and Language · Computer Science 2025-07-01 Kuang Wang , Xianfei Li , Shenghao Yang , Li Zhou , Feng Jiang , Haizhou Li

Medical dialogue systems (MDS) enhance patient-physician communication, improve healthcare accessibility, and reduce costs. However, acquiring suitable data to train these systems poses significant challenges. Privacy concerns prevent the…

Computation and Language · Computer Science 2024-08-13 Trisha Das , Dina Albassam , Jimeng Sun

AI based mental health diagnosis is often judged by benchmark accuracy, yet in practice its value depends on how psychologists respond whether they accept, adjust, or reject AI suggestions. Mental health makes this especially challenging:…

Human-Computer Interaction · Computer Science 2025-12-11 Filippo Cenacchi , Longbing Cao , Deborah Richards

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

Medical education faces challenges in providing scalable, consistent clinical skills training. Simulation with standardized patients (SPs) develops communication and diagnostic skills but remains resource-intensive and variable in feedback…

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou

Longitudinal health agents must reason across multi-source trajectories that combine continuous device streams, sparse clinical exams, and episodic life events - yet evaluating them is hard: real-world data cannot be released at scale, and…

Artificial Intelligence · Computer Science 2026-04-06 Chao Li , Cailiang Liu , Ang Gao , Kexin Deng , Shu Zhang , Langping Xu , Xiaotong Shi , Xionghao Ding , Jian Pei , Xun Jiang