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Segmentation is the identification of anatomical regions of interest, such as organs, tissue, and lesions, serving as a fundamental task in computer-aided diagnosis in medical imaging. Although deep learning models have achieved remarkable…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Tianyi Ren , Daniel Low , Pittra Jaengprajak , Juampablo Heras Rivera , Jacob Ruzevick , Mehmet Kurt

While deep neural networks have achieved remarkable performance, they tend to lack transparency in prediction. The pursuit of greater interpretability in neural networks often results in a degradation of their original performance. Some…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Hefeng Wu , Hao Jiang , Keze Wang , Ziyi Tang , Xianghuan He , Liang Lin

Transparency of Machine Learning models used for decision support in various industries becomes essential for ensuring their ethical use. To that end, feature attribution methods such as SHAP (SHapley Additive exPlanations) are widely used…

Machine Learning · Computer Science 2022-12-08 Anna Bogdanova , Akira Imakura , Tetsuya Sakurai , Tomoya Fujii , Teppei Sakamoto , Hiroyuki Abe

Most existing interpretable methods explain a black-box model in a post-hoc manner, which uses simpler models or data analysis techniques to interpret the predictions after the model is learned. However, they (a) may derive contradictory…

Machine Learning · Computer Science 2020-01-22 Mengzhuo Guo , Qingpeng Zhang , Xiuwu Liao , Daniel Dajun Zeng

Principal component analysis (PCA) is a tool to capture factors that explain variation in data. Across domains, data are now collected across multiple contexts (for example, individuals with different diseases, cells of different types, or…

Machine Learning · Statistics 2026-01-22 Kexin Wang , Salil Bhate , João M. Pereira , Joe Kileel , Matylda Figlerowicz , Anna Seigal

Black box models in machine learning have demonstrated excellent predictive performance in complex problems and high-dimensional settings. However, their lack of transparency and interpretability restrict the applicability of such models in…

Machine Learning · Computer Science 2020-06-09 Numair Sani , Jaron Lee , Razieh Nabi , Ilya Shpitser

A large number of algorithms in machine learning, from principal component analysis (PCA), and its non-linear (kernel) extensions, to more recent spectral embedding and support estimation methods, rely on estimating a linear subspace from…

Machine Learning · Statistics 2014-08-22 Alessandro Rudi , Guille D. Canas , Lorenzo Rosasco

Explainability is essential for neural networks that model long time series, yet most existing explainable AI methods only produce point-wise importance scores and fail to capture temporal structures such as trends, cycles, and regime…

Machine Learning · Computer Science 2025-12-02 Ziqian Wang , Yuxiao Cheng , Jinli Suo

Model Predictive Control (MPC) is widely used to operate safety-critical infrastructure by predicting future trajectories and optimizing control actions. However, nonlinear dynamics, hard safety constraints, and numerical optimization often…

Artificial Intelligence · Computer Science 2026-05-12 Ramesh Arvind Naagarajan , Zühal Wagner , Stefan Streif

Industrial processes generate complex data that challenge fault detection systems, often yielding opaque or underwhelming results despite advanced machine learning techniques. This study tackles such difficulties using the Tennessee Eastman…

Machine Learning · Computer Science 2025-10-29 Pedro Cortes dos Santos , Matheus Becali Rocha , Renato A Krohling

Survival analysis is central to clinical research, informing patient prognoses, guiding treatment decisions, and optimising resource allocation. Accurate time-to-event predictions not only improve quality of life but also reveal risk…

Side-channel analysis (SCA) poses a real-world threat by exploiting unintentional physical signals to extract secret information from secure devices. Evaluation labs also use the same techniques to certify device security. In recent years,…

Cryptography and Security · Computer Science 2025-11-21 Sengim Karayalçin , Marina Krček , Stjepan Picek

Interpretable machine learning offers insights into what factors drive a certain prediction of a black-box system. A large number of interpreting methods focus on identifying explanatory input features, which generally fall into two main…

Machine Learning · Computer Science 2023-06-02 Vy Vo , Van Nguyen , Trung Le , Quan Hung Tran , Gholamreza Haffari , Seyit Camtepe , Dinh Phung

Industrial Cyber-Physical Systems (CPS) are sensitive infrastructure from both safety and economics perspectives, making their reliability critically important. Machine Learning (ML), specifically deep learning, is increasingly integrated…

Machine Learning · Computer Science 2026-04-09 Annemarie Jutte , Uraz Odyurt

Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can…

Machine Learning · Computer Science 2019-08-06 Qingzhu Gao , Humberto Gonzalez , Parvez Ahammad

SHAP explanations are a popular feature-attribution mechanism for explainable AI. They use game-theoretic notions to measure the influence of individual features on the prediction of a machine learning model. Despite a lot of recent…

Artificial Intelligence · Computer Science 2021-02-02 Guy Van den Broeck , Anton Lykov , Maximilian Schleich , Dan Suciu

Ordinary differential equation models have become a standard tool for the mechanistic description of biochemical processes. If parameters are inferred from experimental data, such mechanistic models can provide accurate predictions about…

Quantitative Methods · Quantitative Biology 2018-10-12 Fabian Fröhlich , Carolin Loos , Jan Hasenauer

Most recent work on interpretability of complex machine learning models has focused on estimating $\textit{a posteriori}$ explanations for previously trained models around specific predictions. $\textit{Self-explaining}$ models where…

Machine Learning · Computer Science 2018-12-05 David Alvarez-Melis , Tommi S. Jaakkola

Machine learning solutions for pattern classification problems are nowadays widely deployed in society and industry. However, the lack of transparency and accountability of most accurate models often hinders their safe use. Thus, there is a…

Machine Learning · Computer Science 2021-12-24 Gonzalo Nápoles , Yamisleydi Salgueiro , Isel Grau , Maikel Leon Espinosa

Sparse principal component analysis (sparse PCA) is a widely used technique for dimensionality reduction in multivariate analysis, addressing two key limitations of standard PCA. First, sparse PCA can be implemented in high-dimensional low…

Methodology · Statistics 2025-10-07 Jan O. Bauer