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Explaining the predictions of opaque machine learning algorithms is an important and challenging task, especially as complex models are increasingly used to assist in high-stakes decisions such as those arising in healthcare and finance.…

Machine Learning · Computer Science 2022-06-29 David S. Watson

A number of techniques have been proposed to explain a machine learning model's prediction by attributing it to the corresponding input features. Popular among these are techniques that apply the Shapley value method from cooperative game…

Machine Learning · Computer Science 2020-06-29 Luke Merrick , Ankur Taly

With machine learning models being increasingly used to aid decision making even in high-stakes domains, there has been a growing interest in developing interpretable models. Although many supposedly interpretable models have been proposed,…

Artificial Intelligence · Computer Science 2021-08-17 Forough Poursabzi-Sangdeh , Daniel G. Goldstein , Jake M. Hofman , Jennifer Wortman Vaughan , Hanna Wallach

Extracting meaningful latent representations from high-dimensional sequential data is a crucial challenge in machine learning, with applications spanning natural science and engineering. We introduce InfoDPCCA, a dynamic probabilistic…

Machine Learning · Computer Science 2025-06-11 Shiqin Tang , Shujian Yu

Machine Learning explainability techniques have been proposed as a means of `explaining' or interrogating a model in order to understand why a particular decision or prediction has been made. Such an ability is especially important at a…

Machine Learning · Statistics 2022-02-28 Matthew J. Vowels

Mechanistic Interpretability (MI) aims to reverse-engineer model behaviors by identifying functional sub-networks. Yet, the scientific validity of these findings depends on their stability. In this work, we argue that circuit discovery is…

Machine Learning · Computer Science 2026-02-04 Maxime Méloux , François Portet , Maxime Peyrard

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

Machine Learning · Computer Science 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Recent years have seen a boom in interest in machine learning systems that can provide a human-understandable rationale for their predictions or decisions. However, exactly what kinds of explanation are truly human-interpretable remains…

Machine Learning · Computer Science 2019-08-30 Isaac Lage , Emily Chen , Jeffrey He , Menaka Narayanan , Been Kim , Sam Gershman , Finale Doshi-Velez

The use of algorithm-agnostic approaches is an emerging area of research for explaining the contribution of individual features towards the predicted outcome. Whilst there is a focus on explaining the prediction itself, a little has been…

Machine Learning · Computer Science 2022-11-07 Guilherme Dean Pelegrina , Sajid Siraj

Sparse Autoencoders (SAEs) are a prominent tool in mechanistic interpretability (MI) for decomposing neural network activations into interpretable features. However, the aspiration to identify a canonical set of features is challenged by…

Machine Learning · Computer Science 2025-05-27 Xiangchen Song , Aashiq Muhamed , Yujia Zheng , Lingjing Kong , Zeyu Tang , Mona T. Diab , Virginia Smith , Kun Zhang

Genetic mutations frequently disrupt protein structure, stability, and solubility, acting as primary drivers for a wide spectrum of diseases. Despite the critical importance of these molecular alterations, existing computational models…

Spectral Theory · Mathematics 2026-01-21 Yiming Ren , Junjie Wee , Xi Chen , Grace Qian , Guo-Wei Wei

Machine learning methods have been remarkably successful for a wide range of application areas in the extraction of essential information from data. An exciting and relatively recent development is the uptake of machine learning in the…

Machine Learning · Computer Science 2020-03-13 Ribana Roscher , Bastian Bohn , Marco F. Duarte , Jochen Garcke

Background and Aims: Large language models (LLMs) have shown remarkable generalization and transfer capabilities by learning from vast corpora of text and web data. Their semantic representations allow cross-task knowledge transfer and…

Machine Learning · Computer Science 2025-09-25 Yuqi Jin , Zhenhao Shuai , Zihan Hu , Weiteng Zhang , Weihao Xie , Jianwei Shuai , Xian Shen , Zhen Feng

Explainability techniques for data-driven predictive models based on artificial intelligence and machine learning algorithms allow us to better understand the operation of such systems and help to hold them accountable. New transparency…

Machine Learning · Computer Science 2022-09-09 Kacper Sokol , Alexander Hepburn , Raul Santos-Rodriguez , Peter Flach

Recently, SHapley Additive exPlanations (SHAP) has been widely utilized in various research domains. This is particularly evident in application fields, where SHAP analysis serves as a crucial tool for identifying biomarkers and assisting…

Computation · Statistics 2026-02-02 Kyungjin Kim , Youngro Lee , Jongmo Seo

The main shortage of principle component analysis (PCA) based anomaly detection models is their interpretability. In this paper, our goal is to propose an interpretable PCA-based model for anomaly detection and interpretation. The propose…

Numerical Analysis · Computer Science 2016-05-17 Xingyan Bin , Ying Zhao , Bilong Shen

Principal component analysis (PCA) is a well-known linear dimension-reduction method that has been widely used in data analysis and modeling. It is an unsupervised learning technique that identifies a suitable linear subspace for the input…

Machine Learning · Statistics 2021-09-10 Shaojie Xu , Joel Vaughan , Jie Chen , Agus Sudjianto , Vijayan Nair

Neural networks (NNs), with their powerful nonlinear mapping and end-to-end capabilities, are widely applied in mechanical intelligent fault diagnosis (IFD). However, as typical black-box models, they pose challenges in understanding their…

Machine Learning · Computer Science 2025-02-11 Qian Chen , Xingjian Dong , Kui Hu , Kangkang Chen , Zhike Peng , Guang Meng

Deep learning has achieved remarkable success in processing and managing unstructured data. However, its "black box" nature imposes significant limitations, particularly in sensitive application domains. While existing interpretable machine…

Machine Learning · Computer Science 2025-02-11 Wen-Dong Jiang , Chih-Yung Chang , Show-Jane Yen , Diptendu Sinha Roy
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