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Interpretability is central for scientific machine learning, as understanding \emph{why} models make predictions enables hypothesis generation and validation. While tabular foundation models show strong performance, existing explanation…

Machine Learning · Computer Science 2026-04-01 Luan Borges Teodoro Reis Sena , Francisco Galuppo Azevedo

SHAP is a popular method for measuring variable importance in machine learning models. In this paper, we study the algorithm used to estimate SHAP scores and outline its connection to the functional ANOVA decomposition. We use this…

Methodology · Statistics 2022-11-14 Andrew Herren , P. Richard Hahn

Deep neural networks have demonstrated remarkable performance across various domains, yet their decision-making processes remain opaque. Although many explanation methods are dedicated to bringing the obscurity of DNNs to light, they…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Kanglong Fan , Yunqiao Yang , Chen Ma

Over the years, Principal Component Analysis (PCA) has served as the baseline approach for dimensionality reduction in gene expression data analysis. It primary objective is to identify a subset of disease-causing genes from a vast pool of…

Algebraic Topology · Mathematics 2023-06-13 Sean Cottrell , Rui Wang , Guowei Wei

Explaining complex or seemingly simple machine learning models is an important practical problem. We want to explain individual predictions from a complex machine learning model by learning simple, interpretable explanations. Shapley values…

Machine Learning · Statistics 2020-02-07 Kjersti Aas , Martin Jullum , Anders Løland

Being able to interpret, or explain, the predictions made by a machine learning model is of fundamental importance. This is especially true when there is interest in deploying data-driven models to make high-stakes decisions, e.g. in…

Machine Learning · Computer Science 2019-10-01 An-phi Nguyen , María Rodríguez Martínez

Machine and deep learning have grown in popularity and use in biological research over the last decade but still present challenges in interpretability of the fitted model. The development and use of metrics to determine features driving…

Machine Learning · Statistics 2025-07-31 Daniel Claborne , Javier Flores , Samantha Erwin , Luke Durell , Rachel Richardson , Ruby Fore , Lisa Bramer

Observations of molecular lines are a key tool to determine the main physical properties of prestellar cores. However, not all the information is retained in the observational process or easily interpretable, especially when a larger number…

Astrophysics of Galaxies · Physics 2025-10-08 T. Grassi , M. Padovani , D. Galli , N. Vaytet , S. S. Jensen , E. Redaelli , S. Spezzano , S. Bovino , P. Caselli

What is it to interpret the outputs of an opaque machine learning model. One approach is to develop interpretable machine learning techniques. These techniques aim to show how machine learning models function by providing either model…

Machine Learning · Computer Science 2024-09-06 Andrew Smart , Atoosa Kasirzadeh

In recent years, explainable machine learning methods have been very successful. Despite their success, most explainable machine learning methods are applied to black-box models without any domain knowledge. By incorporating domain…

Machine Learning · Computer Science 2023-09-26 Dangxing Chen

Principal Component Analysis (PCA) and its nonlinear extension Kernel PCA (KPCA) are widely used across science and industry for data analysis and dimensionality reduction. Modern deep learning tools have achieved great empirical success,…

Machine Learning · Computer Science 2023-02-23 Francesco Tonin , Qinghua Tao , Panagiotis Patrinos , Johan A. K. Suykens

Optical spectral-temporal signatures extracted from videos of explosions provide information for identifying characteristics of the corresponding explosive devices. Currently, the identification is done using heuristic algorithms and direct…

Machine Learning · Computer Science 2020-10-26 Katherine Goode , Daniel Ries , Joshua Zollweg

Bottom-up coarse-grained molecular dynamics models are parameterized using complex effective Hamiltonians. These models are typically optimized to approximate high dimensional data from atomistic simulations. In contrast, human validation…

Chemical Physics · Physics 2021-09-16 Aleksander Evren Paetzold Durumeric , Gregory A. Voth

Feature importance estimates that inform users about the degree to which given inputs influence the output of a predictive model are crucial for understanding, validating, and interpreting machine-learning models. However, providing fast…

Machine Learning · Computer Science 2019-10-29 Patrick Schwab , Walter Karlen

The stability of chemically complex nanoparticles is governed by an immense configurational space arising from heterogeneous local atomic environments across surface and interior regions. Efficiently identifying low-energy configurations…

With the growing pervasiveness of artificial intelligence, the ability to explain the inferences made by machine learning models has become increasingly important. Numerous techniques for model explainability have been proposed, with…

Human-Computer Interaction · Computer Science 2026-04-08 Nicola Rossberg , Bennett Kleinberg , Barry O'Sullivan , Luca Longo , Andrea Visentin

Deep learning continues to revolutionize an ever-growing number of critical application areas including healthcare, transportation, finance, and basic sciences. Despite their increased predictive power, model transparency and human…

Machine Learning · Computer Science 2020-04-28 Benjamin Shickel , Parisa Rashidi

Explainable AI aims to overcome the black-box nature of complex ML models like neural networks by generating explanations for their predictions. Explanations often take the form of a heatmap identifying input features (e.g. pixels) that are…

Machine Learning · Computer Science 2024-04-16 Pattarawat Chormai , Jan Herrmann , Klaus-Robert Müller , Grégoire Montavon

Sparse principal component analysis (SPCA) has emerged as a powerful technique for modern data analysis, providing improved interpretation of low-rank structures by identifying localized spatial structures in the data and disambiguating…

To reduce the heavy computational burden of reactive power optimization of distribution networks, machine learning models are receiving increasing attention. However, most machine learning models (e.g., neural networks) are usually…

Systems and Control · Electrical Eng. & Systems 2023-11-08 Wenlong Liao , Benjamin Schäfer , Dalin Qin , Gonghao Zhang , Zhixian Wang , Zhe Yang