English
Related papers

Related papers: RAFT-UP: Robust Alignment for Spatial Transcriptom…

200 papers

Spatial transcriptomics (ST) enables simultaneous mapping of tissue morphology and spatially resolved gene expression, offering unique opportunities to study tumor microenvironment heterogeneity. Here, we introduce a computational framework…

Quantitative Methods · Quantitative Biology 2026-04-27 Ling Liao , Changhuei Yang , Maxim Artyomov , Mark Watson , Adam Kepecs , Haowen Zhou , Alexey Sergushichev , Richard Cote

Comparing data defined over space and time is notoriously hard, because it involves quantifying both spatial and temporal variability, while at the same time taking into account the chronological structure of data. Dynamic Time Warping…

Machine Learning · Statistics 2019-11-12 Hicham Janati , Marco Cuturi , Alexandre Gramfort

Cells in multicellular organisms coordinate to form structural and functional niches. With spatial transcriptomics (ST) enabling gene expression profiling in spatial contexts, it has been revealed that spatial niches serve as cohesive and…

Quantitative Methods · Quantitative Biology 2026-05-26 Mo Chen , Minsheng Hao , Xinquan Liu , Lin Deng , Peng Liu , Chen Li , Dongfang Wang , Kui Hua , Liang Guo , Xuegong Zhang , Lei Wei

Spatial Transcriptomics (ST) allows a high-resolution measurement of RNA sequence abundance by systematically connecting cell morphology depicted in Hematoxylin and Eosin (H&E) stained histology images to spatially resolved gene…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Sichen Zhu , Yuchen Zhu , Molei Tao , Peng Qiu

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

Spatial transcriptomics is an emerging field that enables the identification of functional regions based on the spatial distribution of gene expression. Integrating this functional information present in transcriptomic data with structural…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Shanaka Liyanaarachchi , Chathurya Wijethunga , Shihab Aaqil Ahamed , Akthas Absar , Ranga Rodrigo

The distance transform (DT) and its many variations are ubiquitous tools for image processing and analysis. In many imaging scenarios, the images of interest are corrupted by noise. This has a strong negative impact on the accuracy of the…

Computer Vision and Pattern Recognition · Computer Science 2020-09-14 Johan Öfverstedt , Joakim Lindblad , Nataša Sladoje

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi

Predicting accurate normal maps of objects from two-dimensional images in regions of complex structure and spatial material variations is challenging using photometric stereo methods due to the influence of surface reflection properties…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Kai Luo , Yakun Ju , Lin Qi , Kaixuan Wang , Junyu Dong

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

Remote sensing (RS) images are important to monitor and survey earth at varying spatial scales. Continuous observations from various RS sources complement single observations to improve applications. Fusion into single or multiple images…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Hessah Albanwan

Spatial transcriptomics (ST) technologies have revolutionized the study of gene expression patterns in tissues by providing multimodality data in transcriptomic, spatial, and morphological, offering opportunities for understanding tissue…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Zelin Zang , Liangyu Li , Yongjie Xu , Chenrui Duan , Kai Wang , Yang You , Yi Sun , Stan Z. Li

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Hongyi Wang , Xiuju Du , Jing Liu , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

The recent advancement of spatial transcriptomics (ST) allows to characterize spatial gene expression within tissue for discovery research. However, current ST platforms suffer from low resolution, hindering in-depth understanding of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Xiaofei Wang , Xingxu Huang , Stephen J. Price , Chao Li

Text-to-image flow matching transformers degrade sharply in long-tail settings: tail-class outputs collapse in fidelity and diversity, limiting their value as synthetic augmentation for rare conditions. We trace this to low head-versus-tail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Felix Nützel , Mischa Dombrowski , Bernhard Kainz

Spatial transcriptomics (ST) has advanced significantly in the last few years. Such advancement comes with the urgent need for novel computational methods to handle the unique challenges of ST data analysis. Many artificial intelligence…

Machine Learning · Computer Science 2022-03-21 Yijun Li , Stefan Stanojevic , Lana X. Garmire

With the rapid development of the latest Spatially Resolved Transcriptomics (SRT) technology, which allows for the mapping of gene expression within tissue sections, the integrative analysis of multiple SRT data has become increasingly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Donghai Fang , Fangfang Zhu , Wenwen Min

Sleep staging is critical to assess sleep quality and diagnose disorders. Despite advancements in artificial intelligence enabling automated sleep staging, significant challenges remain: (1) Simultaneously extracting prominent temporal and…

Neurons and Cognition · Quantitative Biology 2025-09-26 Jingying Ma , Qika Lin , Ziyu Jia , Mengling Feng

Space-time modulated metasurfaces (STMMs) are a newly investigated technology for next 6G generation wireless communication networks. An STMM augments the spatial phase function with a time-varying one across the elements, allowing for the…

Signal Processing · Electrical Eng. & Systems 2023-12-08 Marouan Mizmizi , Dario Tagliaferri , Umberto Spagnolini

Spatial transcriptomics (ST) maps gene expression within tissue at individual spots, making it a valuable resource for multimodal representation learning. Additionally, ST inherently contains rich hierarchical information both across and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Xulin Chen , Junzhou Huang