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Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell…

Genomics · Quantitative Biology 2025-12-15 Hiren Madhu , João Felipe Rocha , Tinglin Huang , Siddharth Viswanath , Smita Krishnaswamy , Rex Ying

Spatial Transcriptomics (ST) provides spatially resolved gene expression profiles within intact tissue architecture, enabling molecular analysis in histological context. However, the high cost, limited throughput, and restricted data…

Machine Learning · Computer Science 2026-03-31 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

This paper investigates the problems large-scale distributed composite convex optimization, with motivations from a broad range of applications, including multi-agent systems, federated learning, smart grids, wireless sensor networks,…

Optimization and Control · Mathematics 2025-12-16 Maoran Wang , Xingju Cai , Yongxin Chen

Fine-grained spatio-temporal learning is crucial for freehand 3D ultrasound reconstruction. Previous works mainly resorted to the coarse-grained spatial features and the separated temporal dependency learning and struggles for fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Zhongnuo Yan , Xin Yang , Mingyuan Luo , Jiongquan Chen , Rusi Chen , Lian Liu , Dong Ni

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Recently, joint registration and segmentation has been formulated in a deep learning setting, by the definition of joint loss functions. In this work, we investigate joining these tasks at the architectural level. We propose a registration…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Laurens Beljaards , Mohamed S. Elmahdy , Fons Verbeek , Marius Staring

The rapid development of spatial transcriptomics(ST) enables the measurement of gene expression at spatial resolution, making it possible to simultaneously profile the gene expression, spatial locations of spots, and the matched…

Artificial Intelligence · Computer Science 2024-06-19 Changxi Chi , Hang Shi , Qi Zhu , Daoqiang Zhang , Wei Shao

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such…

Applications · Statistics 2026-04-22 Pritam Dey , Rajarshi Guhaniyogi , Yang Ni , Bani K. Mallick

Whole slide images (WSIs) enable weakly supervised prognostic modeling via multiple instance learning (MIL). Spatial transcriptomics (ST) preserves in situ gene expression, providing a spatial molecular context that complements morphology.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lihe Liu , Xiaoxi Pan , Yinyin Yuan , Lulu Shang

Triggered by the success of transformers in various visual tasks, the spatial self-attention mechanism has recently attracted more and more attention in the computer vision community. However, we empirically found that a typical vision…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Jiayin Sun , Hong Wang , Qiulei Dong

Skeleton-based Temporal Action Segmentation (STAS) aims to segment and recognize various actions from long, untrimmed sequences of human skeletal movements. Current STAS methods typically employ spatio-temporal modeling to establish…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Haoyu Ji , Bowen Chen , Weihong Ren , Wenze Huang , Zhihao Yang , Zhiyong Wang , Honghai Liu

Spatial transcriptomics (ST) enables spatially resolved gene profiling but remains expensive and low-throughput, limiting large-cohort studies and routine clinical use. Predicting spatial gene expression from routine hematoxylin and eosin…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Changfan Wang , Xinran Wang , Donghai Liu , Fei Su , Lulu Sun , Zhicheng Zhao , Zhu Meng

Space-time adaptive processing (STAP) is one of the most effective approaches to suppressing ground clutters in airborne radar systems. It basically takes two forms, i.e., full-dimension STAP (FD-STAP) and reduced-dimension STAP (RD-STAP).…

Information Theory · Computer Science 2022-02-11 Di Song , Shengyao Chen , Feng Xi , Zhong Liu

In agriculture, the majority of vision systems perform still image classification. Yet, recent work has highlighted the potential of spatial and temporal cues as a rich source of information to improve the classification performance. In…

Robotics · Computer Science 2022-06-28 Claus Smitt , Michael Halstead , Alireza Ahmadi , Chris McCool

This paper introduces a new algorithm for trajectory optimization, Decoupled Reduced-space and Adaptive Feasibility-repair Trajectory Optimization (DRAFTO). It first constructs a constrained objective that accounts for smoothness, safety,…

Robotics · Computer Science 2026-03-13 Yichang Feng , Xiao Liang , Minghui Zheng

In recent years, the advent of spatial transcriptomics (ST) technology has unlocked unprecedented opportunities for delving into the complexities of gene expression patterns within intricate biological systems. Despite its transformative…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Wenwen Min , Zhiceng Shi , Jun Zhang , Jun Wan , Changmiao Wang

In distributed and federated learning algorithms, communication overhead is often reduced by performing multiple local updates between communication rounds. However, due to data heterogeneity across nodes and the local gradient noise within…

Machine Learning · Computer Science 2025-12-02 Yan Huang , Jinming Xu , Jiming Chen , Karl Henrik Johansson

Simultaneous Localization and Mapping (SLAM) is pivotal in robotics, with photorealistic scene reconstruction emerging as a key challenge. To address this, we introduce Computational Alignment for Real-Time Gaussian Splatting SLAM (CaRtGS),…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Dapeng Feng , Zhiqiang Chen , Yizhen Yin , Shipeng Zhong , Yuhua Qi , Hongbo Chen

Accurate photometric redshift estimation is critical for observational cosmology, especially in large-scale surveys where spectroscopic measurements are impractical. Traditional approaches include template fitting and machine learning, each…

Instrumentation and Methods for Astrophysics · Physics 2026-04-15 Jonas Chris Ferrao , Dickson Dias , Pranav Naik , Glory D'Cruz , Anish Naik , Siya Khandeparkar , Manisha Gokuldas Fal Dessai
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