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Related papers: The FLASH enigma

200 papers

The processes of energy gain and redistribution in a dense gas subject to an intense ultrashort laser pulse are investigated theoretically for the case of high-pressure argon. The electrons released via strong-field ionization and driven by…

Purpose: This study aims to investigate the impact of the beam temporal profile on the radical dynamics and inter-track interactions of FLASH radiotherapy, supporting parameter optimization for the equipment development and clinical…

We demonstrate analytically and numerically that focusing of high harmonics produced by the reflection of a few femtosecond laser pulse from a concave plasma surface opens a new way towards unprecedentally high intensities. The key features…

Optics · Physics 2007-05-23 S. Gordienko , A. Pukhov , O. Shorokhov , T. Baeva

The density of cosmic rays inside molecular clouds determines the ionization rate in the dense cores where stars form. It is also one of the drivers of astrochemistry leading to the creation of complex molecules. Through Fermi Large Area…

High Energy Astrophysical Phenomena · Physics 2023-01-18 Rui-zhi Yang , Guang-Xing Li , Emma de Oña Wilhelmi , Yu-Dong Cui , Bing Liu , Felix Aharonian

The reflection of intense laser radiation from solids appears as a result of relativistic dynamics of the electrons driven by both incoming and self-generated electromagnetic fields at the periphery of the emerging dense plasma. In the case…

Plasma Physics · Physics 2019-05-22 B. Svedung Wettervik , M. Marklund , A. Gonoskov

Tumor cells develop different features to adapt to environmental conditions. A prominent example is the ability of tumor cells to switch between migratory and proliferative phenotypes, a phenomenon known as go-or-grow mechanism. It is…

Tissues and Organs · Quantitative Biology 2014-07-14 Katrin Böttger , Haralambos Hatzikirou , Anja Voss-Boehme , Miguel A. Herrero , Andreas Deutsch

In outside the body HIFU treatment that focused ultrasound beams hit severely with cancer tissue layer especially the soft one, at the time of passage of the body different layers as long as they want to reach tumor, put their own way…

Laser illumination of tissue results in a characteristic fluorescence emission spectrum whose features depend on the type of tissue, viz., healthy, adenoma or malignant. Hence measurement of the fluorescence is potentially a rapid and…

We present in silico simulations and mathematical analyses supporting several hypotheses that explain the saturation expressed in the fractional cell kill law that governs the lysis of tumor cells by cytotoxic CD8 + T cells (CTLs). In order…

Tissues and Organs · Quantitative Biology 2016-08-30 Álvaro G. López , Jesús M. Seoane , Miguel A. F. Sanjuán

We solve the quasiclassical problem of tunneling through an external potential barrier in a dense plasma, where the tunneling particles undergo simultaneous collisions with other particles in thermodynamic equilibrium. Under such conditions…

Astrophysics · Physics 2007-05-23 V. I. Savchenko

In recent years, ultra-high dose rate (FLASH) radiotherapy has become a novel cancer treatment technique because of its similar tumor-killing efficacy as conventional particle therapy while significantly protecting normal tissues. However,…

Accelerator Physics · Physics 2025-03-04 X. Ding , S. Ruan , H. Ren , G. Wang , R. H. Zhu , J. C. Yang , H. Zhao

The entropy production rate of cancer cell is always higher than healthy cell under the case of no external field applied. Different entropy production between two kinds of cells determines the direction of entropy flow among cells. The…

Cell Behavior · Quantitative Biology 2009-11-13 Liaofu Luo

The success of chemotharapy in soft matter as a survival is found in the paper. Therefore, it is found the analogous tumor stretching force in soft matter; ultrasonography is performed for this tumor; restoration in soft matter with such a…

Other Quantitative Biology · Quantitative Biology 2014-05-19 I. Trifonova , G. Kurteva , S. Z. Stefanov

Fast Radio Bursts (FRBs), with a typical duration of 1 ms and 1 Jy flux density at GHz frequencies, have brightness temperatures exceeding 1e33 K, requiring a coherent emission process. This can be achieved by bunching particles in volumes…

High Energy Astrophysical Phenomena · Physics 2016-11-15 Gabriele Ghisellini

Diffuse interstellar clouds show large abundances of H_3^+ which can be maintained only by a high ionization rate of H_2. Cosmic rays are the dominant ionization mechanism in this environment, so the large ionization rate implies a high…

High Energy Astrophysical Phenomena · Physics 2011-02-11 Nick Indriolo , Brian D. Fields , Benjamin J. McCall

Mutation-induced drug resistance in cancer often causes the failure of therapies and cancer recurrence, despite an initial tumor reduction. The timing of such cancer recurrence is governed by a balance between several factors such as…

Probability · Mathematics 2013-07-22 Jasmine Foo , Kevin Leder

It is generally accepted that radio relics are the result of synchrotron emission from shock-accelerated electrons. Current models, however, are still unable to explain several aspects of their formation. In this paper, we focus on three…

High Energy Astrophysical Phenomena · Physics 2026-02-02 Joseph Whittingham , Christoph Pfrommer , Maria Werhahn , Léna Jlassi , Philipp Girichidis

The standard theory of nuclear fusion rates in a strongly interacting plasma can be (correctly) derived only when the energy release, Q, is large compared to other energies in the problem. We exhibit a result for rates that provides a basis…

Solar and Stellar Astrophysics · Physics 2010-05-25 R. F. Sawyer

The FLASH effect, characterized by potential sparing of organs at risk (OAR) through ultra-high dose rate irradiation, has garnered significant attention for its capability to address indications previously untreatable at conventional dose…

Medical Physics · Physics 2024-10-16 S. Wuyckens , M. Chocan Vera , R. Nilsson , V. Wase , D. Di Perri , X. Geets , E. Sterpin , J. A. Lee

Turbulence is a challenging feature common to a wide range of complex phenomena. Random fibre lasers are a special class of lasers in which the feedback arises from multiple scattering in a one-dimensional disordered cavity-less medium.…