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Despite their widespread use, large language models (LLMs) are known to hallucinate incorrect information and be poorly calibrated. This makes the uncertainty quantification of these models of critical importance, especially in high-stakes…

Machine Learning · Computer Science 2025-06-27 Colin Samplawski , Adam D. Cobb , Manoj Acharya , Ramneet Kaur , Susmit Jha

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Many advanced Large Language Model (LLM) applications require long-context processing, but the self-attention module becomes a bottleneck during the prefilling stage of inference due to its quadratic time complexity with respect to sequence…

Machine Learning · Computer Science 2025-06-02 Xiaodong Ji , Hailin Zhang , Fangcheng Fu , Bin Cui

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Purpose: Machine learning is broadly used for clinical data analysis. Before training a model, a machine learning algorithm must be selected. Also, the values of one or more model parameters termed hyper-parameters must be set. Selecting…

Machine Learning · Computer Science 2018-12-10 Xueqiang Zeng , Gang Luo

The recent success of Large Language Models (LLMs) has gained significant attention in both academia and industry. Substantial efforts have been made to enhance the zero- and few-shot generalization capabilities of open-source LLMs through…

Computation and Language · Computer Science 2023-10-03 Zongxi Li , Xianming Li , Yuzhang Liu , Haoran Xie , Jing Li , Fu-lee Wang , Qing Li , Xiaoqin Zhong

Recent advancements in large language models (LLMs) integrated with external tools and APIs have successfully addressed complex tasks by using in-context learning or fine-tuning. Despite this progress, the vast scale of tool retrieval…

Information Retrieval · Computer Science 2024-10-07 Yuxiang Zhang , Xin Fan , Junjie Wang , Chongxian Chen , Fan Mo , Tetsuya Sakai , Hayato Yamana

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

In robot-assisted minimally invasive surgery, we introduce the Surgical Action Planning (SAP) task, which generates future action plans from visual inputs to address the absence of intraoperative predictive planning in current intelligent…

Computation and Language · Computer Science 2025-04-01 Mengya Xu , Zhongzhen Huang , Jie Zhang , Xiaofan Zhang , Qi Dou

Recently, Large Language Models (LLMs) have gained significant traction in medical domain, especially in developing a QA systems to Medical QA systems for enhancing access to healthcare in low-resourced settings. This paper compares five…

Computation and Language · Computer Science 2026-02-17 Shefayat E Shams Adib , Ahmed Alfey Sani , Ekramul Alam Esham , Ajwad Abrar , Tareque Mohmud Chowdhury

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

Large Language Models (LLMs) are known for their expensive and time-consuming training. Thus, oftentimes, LLMs are fine-tuned to address a specific task, given the pretrained weights of a pre-trained LLM considered a foundation model. In…

Computation and Language · Computer Science 2025-12-05 Eshed Gal , Moshe Eliasof , Javier Turek , Uri Ascher , Eran Treister , Eldad Haber

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy

Multimodal large language models (LLMs) have achieved notable success across various domains, while research in the medical field has largely focused on unimodal images. Meanwhile, current general-domain multimodal models for videos still…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Jiajie Li , Garrett Skinner , Gene Yang , Brian R Quaranto , Steven D Schwaitzberg , Peter C W Kim , Jinjun Xiong

Long-context Large Language Model (LLM) inference faces increasing compute bottlenecks as attention calculations scale with context length, primarily due to the growing KV-cache transfer overhead that saturates High Bandwidth Memory (HBM).…

Hardware Architecture · Computer Science 2025-08-13 Ming-Yen Lee , Faaiq Waqar , Hanchen Yang , Muhammed Ahosan Ul Karim , Harsono Simka , Shimeng Yu

We develop a new efficient sequential approximate leverage score algorithm, SALSA, using methods from randomized numerical linear algebra (RandNLA) for large matrices. We demonstrate that, with high probability, the accuracy of SALSA's…

Machine Learning · Statistics 2024-01-02 Ali Eshragh , Luke Yerbury , Asef Nazari , Fred Roosta , Michael W. Mahoney

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Learning is the important property of Back Propagation Network (BPN) and finding the suitable weights and thresholds during training in order to improve training time as well as achieve high accuracy. Currently, data pre-processing such as…

Neural and Evolutionary Computing · Computer Science 2009-08-12 Roya Asadi , Norwati Mustapha , Nasir Sulaiman