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Large language models (LLMs) have achieved great success in medical question answering and clinical decision-making, promoting the efficiency and popularization of the personalized virtual doctor in society. However, the traditional…

Computation and Language · Computer Science 2025-09-23 Jianbin Zhang , Yulin Zhu , Wai Lun Lo , Richard Tai-Chiu Hsung , Harris Sik-Ho Tsang , Kai Zhou

In-Context Learning (ICL) emerges as a key feature for Large Language Models (LLMs), allowing them to adapt to new tasks by leveraging task-specific examples without updating model parameters. However, ICL faces challenges with increasing…

Machine Learning · Computer Science 2024-10-15 Chengsong Huang , Langlin Huang , Jiaxin Huang

Recently, Large Language Models (LLMs) have rapidly evolved, approaching Artificial General Intelligence (AGI) while benefiting from large-scale reinforcement learning to enhance Human Alignment (HA) and Reasoning. Recent reward-based…

Machine Learning · Computer Science 2025-06-19 Xuerui Su , Shufang Xie , Guoqing Liu , Yingce Xia , Renqian Luo , Peiran Jin , Zhiming Ma , Yue Wang , Zun Wang , Yuting Liu

Antibodies play a central role in the immune response by specifically recognizing and neutralizing antigens, and therapeutic antibodies have become major drugs for cancer and autoimmune diseases. However, their discovery still relies on…

Quantitative Methods · Quantitative Biology 2026-05-29 Xiao Luo

Importance: Emergency department (ED) returns for mental health conditions pose a major healthcare burden, with 24-27% of patients returning within 30 days. Traditional machine learning models for predicting these returns often lack…

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

A primary challenge in large language model (LLM) development is their onerous pre-training cost. Typically, such pre-training involves optimizing a self-supervised objective (such as next-token prediction) over a large corpus. This paper…

Recently, few-shot learning (FSL) has become a popular task that aims to recognize new classes from only a few labeled examples and has been widely applied in fields such as natural science, remote sensing, and medical images. However, most…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Liwen Wu , Wei Wang , Lei Zhao , Zhan Gao , Qika Lin , Shaowen Yao , Zuozhu Liu , Bin Pu

We study the problem of optimizing Large Language Model (LLM) inference scheduling to minimize total latency. LLM inference is an online and multi-task service process and also heavily energy consuming by which a pre-trained LLM processes…

Machine Learning · Computer Science 2025-09-03 Zixi Chen , Yinyu Ye , Zijie Zhou

Large Language Models (LLMs) have shown exceptional capabilities in Natural Language Processing (NLP) across diverse domains. However, their application in specialized tasks such as Legal Judgment Prediction (LJP) for low-resource languages…

Computation and Language · Computer Science 2025-03-03 Mohamed Bayan Kmainasi , Ali Ezzat Shahroor , Amani Al-Ghraibah

Large Language Models (LLMs) are discovered to suffer from accurately retrieving key information. To address this, we propose Mask-Enhanced Autoregressive Prediction (MEAP), a simple yet effective training paradigm that seamlessly…

Computation and Language · Computer Science 2026-03-16 Xialie Zhuang , Zhikai Jia , Jianjin Li , Zhenyu Zhang , Li Shen , Zheng Cao , Shiwei Liu

Recent advancements in self-supervised learning have led to powerful surgical vision encoders capable of spatiotemporal understanding. However, extending these visual foundations to multi-modal reasoning tasks is severely bottlenecked by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Chengan Che , Chao Wang , Jiayuan Huang , Xinyue Chen , Luis C. Garcia-Peraza-Herrera

The rapid growth of large language models (LLMs) presents significant deployment challenges due to their massive computational and memory demands. While model compression, such as network pruning, offers potential solutions, most existing…

Machine Learning · Computer Science 2026-04-07 Ziwei Li , Yuang Ma , Yi Kang

Inference-time computation is a powerful paradigm to enhance the performance of large language models (LLMs), with Best-of-N sampling being a widely used technique. However, this method is computationally expensive, requiring both (1) an…

Computation and Language · Computer Science 2024-10-04 Rohin Manvi , Anikait Singh , Stefano Ermon

Large language models (LLMs) have demonstrated proficiency across various natural language processing (NLP) tasks but often require additional training, such as continual pre-training and supervised fine-tuning. However, the costs…

Computation and Language · Computer Science 2024-06-07 Da Ma , Lu Chen , Pengyu Wang , Hongshen Xu , Hanqi Li , Liangtai Sun , Su Zhu , Shuai Fan , Kai Yu

Bias in AI systems, especially those relying on natural language data, raises ethical and practical concerns. Underrepresentation of certain groups often leads to uneven performance across demographics. Traditional fairness methods, such as…

Computation and Language · Computer Science 2025-10-16 Sai Suhruth Reddy Karri , Yashwanth Sai Nallapuneni , Laxmi Narasimha Reddy Mallireddy , Gopichand G

Neural network pruning is a promising technique to mitigate the excessive computational and memory requirements of large language models (LLMs). Despite its promise, however, progress in this area has diminished, as conventional methods are…

Machine Learning · Computer Science 2026-02-24 Kwanhee Lee , Hyeondo Jang , Dongyeop Lee , Dan Alistarh , Namhoon Lee

This paper presents the overview of the development and fine-tuning of large language models (LLMs) designed specifically for answering medical questions. We are mainly improving the accuracy and efficiency of providing reliable answers to…

Computation and Language · Computer Science 2025-01-30 Aysegul Ucar , Soumik Nayak , Anunak Roy , Burak Taşcı , Gülay Taşcı

Latent Dirichlet Allocation (LDA) is a prominent generative probabilistic model used for uncovering abstract topics within document collections. In this paper, we explore the effectiveness of augmenting topic models with Large Language…

Computation and Language · Computer Science 2025-07-14 Mengze Hong , Chen Jason Zhang , Di Jiang

Structured pruning of large language models (LLMs) offers substantial efficiency improvements by removing entire hidden units, yet current approaches often suffer from significant performance degradation, particularly in zero-shot settings,…

Machine Learning · Computer Science 2025-09-18 Mengting Ai , Tianxin Wei , Sirui Chen , Jingrui He
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