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The integration of medical imaging and clinical text has enabled the emergence of generalist artificial intelligence (AI) systems for healthcare. However, pervasive biases, such as imbalanced disease prevalence, skewed anatomical region…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Cheng Li , Weijian Huang , Jiarun Liu , Hao Yang , Qi Yang , Song Wu , Ye Li , Hairong Zheng , Shanshan Wang

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Diagnostic prediction and clinical reasoning are critical tasks in healthcare applications. While Large Language Models (LLMs) have shown strong capabilities in commonsense reasoning, they still struggle with diagnostic reasoning due to…

Computation and Language · Computer Science 2026-04-28 Yimin Deng , Zhenxi Lin , Yejing Wang , Guoshuai Zhao , Pengyue Jia , Zichuan Fu , Derong Xu , Yefeng Zheng , Xiangyu Zhao , Li Zhu , Xian Wu , Xueming Qian

This study presents DiagCoT, a multi-stage framework that applies supervised fine-tuning to general-purpose vision-language models (VLMs) to emulate radiologists' stepwise diagnostic reasoning using only free-text reports. DiagCoT combines…

Artificial Intelligence · Computer Science 2025-09-09 Yihong Luo , Wenwu He , Zhuo-Xu Cui , Dong Liang

Medical diagnostics is a high-stakes and complex domain that is critical to patient care. However, current evaluations of large language models (LLMs) remain limited in capturing key challenges of clinical diagnostic scenarios. Most rely on…

Computation and Language · Computer Science 2026-04-21 Xiangxu Zhang , Lei Li , Yanyun Zhou , Xiao Zhou , Yingying Zhang , Xian Wu

Although Alzheimer's disease (AD) cannot be reversed or cured, timely diagnosis can significantly reduce the burden of treatment and care. Current research on AD diagnosis models usually regards the diagnosis task as a typical…

Large language models (LLMs) have demonstrated notable potential in medical applications, yet they face substantial challenges in handling complex real-world clinical diagnoses using conventional prompting methods. Current prompt…

Artificial Intelligence · Computer Science 2026-03-02 Wenliang Li , Rui Yan , Xu Zhang , Li Chen , Hongji Zhu , Jing Zhao , Junjun Li , Mengru Li , Wei Cao , Zihang Jiang , Wei Wei , Kun Zhang , Shaohua Kevin Zhou

Clinical text improvement is vital for healthcare efficiency but remains difficult due to limited high-quality data and the complex constraints of medical documentation. While Large Language Models (LLMs) show promise, current approaches…

Computation and Language · Computer Science 2026-02-03 Ziyan Xiao , Yinghao Zhu , Liang Peng , Lequan Yu

Explainable Artificial Intelligence (XAI) is essential for the transparency and clinical adoption of Clinical Decision Support Systems (CDSS). However, the real-world effectiveness of existing XAI methods remains limited and is…

Machine Learning · Computer Science 2026-01-26 Alessandro Gambetti , Qiwei Han , Hong Shen , Claudia Soares

Artificial intelligence holds great promise for expanding access to expert medical knowledge and reasoning. However, most evaluations of language models rely on static vignettes and multiple-choice questions that fail to reflect the…

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

Deep learning-based health status representation learning and clinical prediction have raised much research interest in recent years. Existing models have shown superior performance, but there are still several major issues that have not…

Machine Learning · Computer Science 2019-11-28 Liantao Ma , Junyi Gao , Yasha Wang , Chaohe Zhang , Jiangtao Wang , Wenjie Ruan , Wen Tang , Xin Gao , Xinyu Ma

With the development of deep learning (DL) techniques, rotating machinery intelligent diagnosis has gone through tremendous progress with verified success and the classification accuracies of many DL-based intelligent diagnosis algorithms…

Signal Processing · Electrical Eng. & Systems 2020-08-20 Zhibin Zhao , Tianfu Li , Jingyao Wu , Chuang Sun , Shibin Wang , Ruqiang Yan , Xuefeng Chen

Today's AI systems have human-designed, fixed architectures and cannot autonomously and continuously improve themselves. The advance of AI could itself be automated. If done safely, that would accelerate AI development and allow us to reap…

Artificial Intelligence · Computer Science 2026-03-16 Jenny Zhang , Shengran Hu , Cong Lu , Robert Lange , Jeff Clune

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Improving context faithfulness in large language models is essential for developing trustworthy retrieval augmented generation systems and mitigating hallucinations, especially in long-form question answering (LFQA) tasks or scenarios…

Computation and Language · Computer Science 2025-03-04 Kun Li , Tianhua Zhang , Yunxiang Li , Hongyin Luo , Abdalla Moustafa , Xixin Wu , James Glass , Helen Meng

Artificial Intelligence (AI) is one of the approaches that has been proposed to analyze the collected data (e.g., vibration signals) providing a diagnosis of the asset's operating condition. It is known that models trained with labeled data…

Artificial Intelligence · Computer Science 2022-10-12 Lucas Costa Brito , Gian Antonio Susto , Jorge Nei Brito , Marcus Antonio Viana Duarte

Generative Agents, owing to their precise modeling and simulation capabilities of human behavior, have become a pivotal tool in the field of Artificial Intelligence in Education (AIEd) for uncovering complex cognitive processes of learners.…

Artificial Intelligence · Computer Science 2026-05-11 Wei Zhang , Yihang Cheng , Zhirong Ye , Kezhen Huang

Clinical decision support requires not only correct answers but also clinically valid reasoning. We propose Differential Reasoning Learning (DRL), a framework that improves clinical agents by learning from reasoning discrepancies. From…

Artificial Intelligence · Computer Science 2026-02-11 Jinsong Liu , Yuhang Jiang , Ramayya Krishnan , Rema Padman , Yiye Zhang , Jiang Bian

While recent advancements in Large Language Models have significantly advanced dermatological diagnosis, monolithic LLMs frequently struggle with fine-grained, large-scale multi-class diagnostic tasks and rare skin disease diagnosis owing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Zhangtianyi Chen , Yuhao Shen , Florensia Widjaja , Yan Xu , Liyuan Sun , Zijian Wang , Hongyi Chen , Wufei Dai , Juexiao Zhou
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