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Current Large Language Model (LLM) agents show strong performance in tool use, but lack the crucial capability to systematically learn from their own experiences. While existing frameworks mainly focus on mitigating external knowledge gaps,…

Computation and Language · Computer Science 2026-05-19 Rong Wu , Xiaoman Wang , Jianbiao Mei , Pinlong Cai , Daocheng Fu , Cheng Yang , Licheng Wen , Xuemeng Yang , Yufan Shen , Yuxin Wang , Botian Shi

Large language models (LLMs) are increasingly deployed as conversational tutors in STEM education, yet most systems still rely on a single LLM with a static retrieval-augmented generation (RAG) pipeline over course materials. This design…

Artificial Intelligence · Computer Science 2025-12-02 Yefeng Wu , Yuchen Song , Yecheng Zhao , Ling Wu , Shan Wan

We study how large language models can be used to evolve inventory policies in online, non-stationary environments. Our work is motivated by recent advances in LLM-based evolutionary search, such as AlphaEvolve, which demonstrates strong…

Machine Learning · Computer Science 2026-05-12 Chenyu Huang , Jianghao Lin , Zhengyang Tang , Bo Jiang , Ruoqing Jiang , Benyou Wang , Lai Wei

Trustworthiness and transparency are essential for the clinical adoption of artificial intelligence (AI) in healthcare and biomedical research. Recent deep research systems aim to accelerate evidence-grounded scientific discovery by…

Traditionally, Deep Artificial Neural Networks (DNN's) are trained through gradient descent. Recent research shows that Deep Neuroevolution (DNE) is also capable of evolving multi-million-parameter DNN's, which proved to be particularly…

Neural and Evolutionary Computing · Computer Science 2021-04-14 Daan Klijn , A. E. Eiben

A growing body of research runs human subject evaluations to study whether providing users with explanations of machine learning models can help them with practical real-world use cases. However, running user studies is challenging and…

Human-Computer Interaction · Computer Science 2022-08-23 Valerie Chen , Nari Johnson , Nicholay Topin , Gregory Plumb , Ameet Talwalkar

The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

Machine Learning · Computer Science 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh

Automating scientific discovery requires more than generating papers from ideas. Real research is iterative: hypotheses are challenged from multiple perspectives, experiments fail and inform the next attempt, and lessons accumulate across…

Recent advancements in machine learning algorithms, especially the development of Deep Neural Networks (DNNs) have transformed the landscape of Artificial Intelligence (AI). With every passing day, deep learning based methods are applied to…

Neural and Evolutionary Computing · Computer Science 2020-08-31 Parth Mannan , Ananda Samajdar , Tushar Krishna

The recent development of data-driven AI promises to automate medical diagnosis; however, most AI functions as 'black boxes' to physicians with limited computational knowledge. Using medical imaging as a point of departure, we conducted…

Human-Computer Interaction · Computer Science 2020-01-22 Yao Xie , Melody Chen , David Kao , Ge Gao , Xiang 'Anthony' Chen

Deep Learning has advanced significantly in medical applications, aiding disease diagnosis in Chest X-ray images. However, expanding model capabilities with new data remains a challenge, which Continual Learning (CL) aims to address.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Marina Ceccon , Davide Dalle Pezze , Alessandro Fabris , Gian Antonio Susto

Clinical systems operate in safety-critical environments and are not intended to function autonomously; however, they are currently designed to replicate clinicians' diagnoses rather than assist them in the diagnostic process. To enable…

Human-Computer Interaction · Computer Science 2025-04-07 Kailas Dayanandan , Brejesh Lall

A profound gap persists between artificial intelligence (AI) and clinical practice in medicine, primarily due to the lack of rigorous and cost-effective evaluation methodologies. State-of-the-art and state-of-the-practice AI model…

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Deep learning (DL) systems are increasingly deployed in safety- and security-critical domains including self-driving cars and malware detection, where the correctness and predictability of a system's behavior for corner case inputs are of…

Machine Learning · Computer Science 2017-09-26 Kexin Pei , Yinzhi Cao , Junfeng Yang , Suman Jana

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

Machine Learning · Computer Science 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

With AI agents increasingly deployed as long-running systems, it becomes essential to autonomously construct and continuously evolve customized software to enable interaction within dynamic environments. Yet, existing benchmarks evaluate…

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi