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Hierarchical Multi-Agent Systems provide convenient and relevant ways to analyze, model, and simulate complex systems composed of a large number of entities that interact at different levels of abstraction. In this paper, we introduce…

Machine Learning · Computer Science 2022-04-27 Ahmad Esmaeili , John C. Gallagher , John A. Springer , Eric T. Matson

The densification and expansion of wireless network pose new challenges on interference management and reducing energy consumption. This paper studies energy-efficient resource management in heterogeneous networks by jointly optimizing cell…

Information Theory · Computer Science 2016-02-11 Quan Kuang , Wolfgang Utschick

Single-cell data provide high-dimensional measurements of the transcriptional states of cells, but extracting insights into the regulatory functions of genes, particularly identifying transcriptional mechanisms affected by biological…

Molecular Networks · Quantitative Biology 2025-03-27 Paul Bertin , Joseph D. Viviano , Alejandro Tejada-Lapuerta , Weixu Wang , Stefan Bauer , Fabian J. Theis , Yoshua Bengio

Muilti-modality data are ubiquitous in biology, especially that we have entered the multi-omics era, when we can measure the same biological object (cell) from different aspects (omics) to provide a more comprehensive insight into the…

Genomics · Quantitative Biology 2021-12-15 Xuesong Wang , Zhihang Hu , Tingyang Yu , Ruijie Wang , Yumeng Wei , Juan Shu , Jianzhu Ma , Yu Li

Exploring sparse reward multi-agent reinforcement learning (MARL) environments with traps in a collaborative manner is a complex task. Agents typically fail to reach the goal state and fall into traps, which affects the overall performance…

Artificial Intelligence · Computer Science 2023-06-16 Xuechen Mu , Hankz Hankui Zhuo , Chen Chen , Kai Zhang , Chao Yu , Jianye Hao

Serving Large Language Models (LLMs) is a GPU-intensive task where traditional autoscalers fall short, particularly for modern Prefill-Decode (P/D) disaggregated architectures. This architectural shift, while powerful, introduces…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-28 Rongzhi Li , Ruogu Du , Zefang Chu , Sida Zhao , Chunlei Han , Zuocheng Shi , Yiwen Shao , Huanle Han , Long Huang , Zherui Liu , Shufan Liu

Heterogeneous graphs are widely present in real-world complex networks, where the diversity of node and relation types leads to complex and rich semantics. Efforts for modeling complex relation semantics in heterogeneous graphs are…

Computation and Language · Computer Science 2025-11-25 Wenda Li , Tongya Zheng , Shunyu Liu , Yu Wang , Kaixuan Chen , Hanyang Yuan , Bingde Hu , Zujie Ren , Mingli Song , Gang Chen

Deep research agents, which synthesize information across diverse sources, are significantly constrained by the sequential nature of reasoning. This bottleneck results in high latency, poor runtime adaptability, and inefficient resource…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-31 Lunyiu Nie , Nedim Lipka , Ryan A. Rossi , Swarat Chaudhuri

In a probabilistic cellular automaton in which all local transitions have positive probability, the problem of keeping a bit of information indefinitely is nontrivial, even in an infinite automaton. Still, there is a solution in 2…

Probability · Mathematics 2024-01-26 Peter Gacs

Generating symphonic music requires simultaneously managing high-level structural form and dense, multi-track orchestration. Existing symbolic models often struggle with a "complexity-control imbalance", in which scaling bottlenecks limit…

Sound · Computer Science 2026-04-29 Xuzheng He , Nan Nan , Zhilin Wang , Ziyue Kang , Zhuoru Mo , Ao Li , Yu Pan , Xiaobing Li , Feng Yu , Xiaohong Guan

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Saqib Nazir , Ardhendu Behera

Hierarchical Multi-Label Classification (HMC) faces critical challenges in maintaining structural consistency and balancing loss weighting in Multi-Task Learning (MTL). In order to address these issues, we propose a classifier called HCAL…

Machine Learning · Computer Science 2025-08-20 Ruobing Jiang , Mengzhe Liu , Haobing Liu , Yanwei Yu

Autoregressive decoding inherently limits the inference throughput of Large Language Model (LLM) due to its sequential dependency. Speculative decoding mitigates this by verifying multiple predicted tokens in parallel, but its efficiency…

Computation and Language · Computer Science 2025-10-27 Siran Liu , Yang Ye , Qianchao Zhu , Zane Cao , Yongchao He

This paper introduces Project Synapse, a novel agentic framework designed for the autonomous resolution of last-mile delivery disruptions. Synapse employs a hierarchical multi-agent architecture in which a central Resolution Supervisor…

Artificial Intelligence · Computer Science 2026-01-14 Arin Gopalan Yadav , Varad Dherange , Kumar Shivam

Existing unstructured data analytics systems rely on experts to write code and manage complex analysis workflows, making them both expensive and time-consuming. To address these challenges, we introduce AgenticData, an innovative agentic…

Databases · Computer Science 2025-08-08 Ji Sun , Guoliang Li , Peiyao Zhou , Yihui Ma , Jingzhe Xu , Yuan Li

The search for symmetry as an unusual yet profoundly appealing phenomenon, and the origin of regular, repeating configuration patterns have long been a central focus of complexity science and physics. To better grasp and understand symmetry…

Cellular Automata and Lattice Gases · Physics 2019-07-01 Peter Banda , John Caughman , Martin Cenek , Christof Teuscher

With recent breakthroughs in large language models (LLMs) for reasoning, planning, and complex task generation, artificial intelligence systems are transitioning from isolated single-agent architectures to multi-agent systems with…

Artificial Intelligence · Computer Science 2026-02-17 Linlin Wang , Tianqing Zhu , Laiqiao Qin , Longxiang Gao , Wanlei Zhou

Test-time reinforcement learning (TTRL) offers a label-free paradigm for adapting models using only synthetic signals at inference, but its success hinges on constructing reliable learning signals. Standard approaches such as majority…

Computation and Language · Computer Science 2026-03-03 Ru Wang , Wei Huang , Qi Cao , Yusuke Iwasawa , Yutaka Matsuo , Jiaxian Guo

We present an algorithm for the stochastic simulation of gene expression and heterogeneous population dynamics. The algorithm combines an exact method to simulate molecular-level fluctuations in single cells and a constant-number Monte…

Computational Physics · Physics 2016-08-24 Daniel A. Charlebois , Jukka Intosalmi , Dawn Fraser , Mads Kaern

A central goal in systems biology and drug discovery is to predict the transcriptional response of cells to perturbations. This task is challenging due to the noisy and sparse nature of single-cell measurements, as well as the fact that…

Quantitative Methods · Quantitative Biology 2026-02-10 Chenglei Yu , Chuanrui Wang , Bangyan Liao , Tailin Wu