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Virtual Cell Modeling (VCM) requires models that not only predict perturbation responses, but also support targeted revision when predictions fail. Current LLM-assisted modeling workflows face a refinement-routing problem: prediction…

Language models pretrained on large collections of tabular data have demonstrated their effectiveness in several downstream tasks. However, many of these models do not take into account the row/column permutation invariances, hierarchical…

Machine Learning · Computer Science 2023-10-30 Pei Chen , Soumajyoti Sarkar , Leonard Lausen , Balasubramaniam Srinivasan , Sheng Zha , Ruihong Huang , George Karypis

The transformers have achieved significant accomplishments in the natural language processing as its outstanding parallel processing capabilities and highly flexible attention mechanism. In addition, increasing studies based on transformers…

Computation and Language · Computer Science 2024-07-19 Wei Lan , Guohang He , Mingyang Liu , Qingfeng Chen , Junyue Cao , Wei Peng

Hierarchical text classification (HTC) is a complex subtask under multi-label text classification, characterized by a hierarchical label taxonomy and data imbalance. The best-performing models aim to learn a static representation by…

Computation and Language · Computer Science 2024-02-23 Vidit Jain , Mukund Rungta , Yuchen Zhuang , Yue Yu , Zeyu Wang , Mu Gao , Jeffrey Skolnick , Chao Zhang

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

In real-world data science and enterprise decision-making, critical information is often fragmented across directly queryable structured sources (e.g., SQL, CSV) and "zombie data" locked in unstructured visual documents (e.g., scanned…

Artificial Intelligence · Computer Science 2026-01-30 Ruyi Qi , Zhou Liu , Wentao Zhang

Federated learning (FL) is severely challenged by non-independent and identically distributed (non-IID) client data, a problem that degrades global model performance, especially in multimodal perception settings. Conventional methods often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Jing Liu , Zhengliang Guo , Yan Wang , Xiaoguang Zhu , Yao Du , Zehua Wang , Victor C. M. Leung

We address the task of auto-completing data cells in relational tables. Such tables describe entities (in rows) with their attributes (in columns). We present the CellAutoComplete framework to tackle several novel aspects of this problem,…

Information Retrieval · Computer Science 2020-02-06 Shuo Zhang , Krisztian Balog

Optimizing the cellular network's cell locations is one of the most fundamental problems of network design. The general objective is to provide the desired Quality-of-Service (QoS) with the minimum system cost. In order to meet a growing…

Networking and Internet Architecture · Computer Science 2013-07-23 Weisi Guo , Siyi Wang , Xiaoli Chu , Jiming Chen , Hui Song , Jie Zhang

The remarkable success of diffusion models in text-to-image generation has sparked growing interest in expanding their capabilities to a variety of multi-modal tasks, including image understanding, manipulation, and perception. These tasks…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xinyang Song , Libin Wang , Weining Wang , Shaozhen Liu , Dandan Zheng , Jingdong Chen , Qi Li , Zhenan Sun

As Large Language Models (LLMs) are increasingly deployed as autonomous agents, they face a critical scalability bottleneck known as the "Generalization-Specialization Dilemma." Monolithic agents equipped with extensive toolkits suffer from…

Multiagent Systems · Computer Science 2026-01-16 Sathish Sampath , Anuradha Baskaran

Drug synergy is profoundly influenced by cellular context, as variations in protein interaction landscapes and pathway activities across cell types reshape how drugs act in combination. Most existing models overlook this heterogeneity,…

Quantitative Methods · Quantitative Biology 2026-03-24 Keqin Peng , Guangxin Su , Qinshan Shi , Shuai Gao , Ren Wang , Can Chen , Jun Wen

Current research on large language model (LLM) agents is fragmented: discussions of conceptual frameworks and methodological principles are frequently intertwined with low-level implementation details, causing both readers and authors to…

Artificial Intelligence · Computer Science 2026-02-10 Haoyu Jia , Kento Kawaharazuka , Kei Okada

Current macroeconomic models with agent heterogeneity can be broadly divided into two main groups. Heterogeneous-agent general equilibrium (GE) models, such as those based on Heterogeneous Agent New Keynesian (HANK) or Krusell-Smith (KS)…

Multiagent Systems · Computer Science 2026-02-17 Federico Gabriele , Aldo Glielmo , Marco Taboga

As Large Language Models (LLMs) evolve into persistent scientific collaborators, context window saturation has emerged as a critical bottleneck. Scientific workflows involving iterative data analysis and hypothesis refinement rapidly…

Artificial Intelligence · Computer Science 2026-05-19 Nikola Milosevic

Software-managed heterogeneous memory (HM) provides a promising solution to increase memory capacity and cost efficiency. However, to release the performance potential of HM, we face a problem of data management. Given an application with…

Performance · Computer Science 2019-09-12 Jie Ren , Jiaolin Luo , Kai Wu , Minjia Zhang , Dong Li

Large Language Models (LLMs) have revolutionized Natural Language Processing but exhibit limitations, particularly in autonomously addressing novel challenges such as reasoning and problem-solving. Traditional techniques like…

Multiagent Systems · Computer Science 2024-01-03 Sumedh Rasal

Efficiently solving the Job Shop Scheduling Problem in real-world industrial applications requires policies that are both computationally lean and topologically robust. While Reinforcement Learning has shown potential in automating…

Machine Learning · Computer Science 2026-04-28 Jonathan Hoss , Moritz Link , Noah Klarmann

Hybrid parallelism techniques are essential for efficiently training large language models (LLMs). Nevertheless, current automatic parallel planning frameworks often overlook the simultaneous consideration of node heterogeneity and dynamic…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-04 Ruilong Wu , Xinjiao Li , Yisu Wang , Xinyu Chen , Dirk Kutscher

Techniques for coordination of multi-agent systems are vast and varied, often utilizing purpose-built solvers or controllers with tight coupling to the types of systems involved or the coordination goal. In this paper, we introduce a…

Optimization and Control · Mathematics 2025-04-07 Tyler Hanks , Hans Riess , Samuel Cohen , Trevor Gross , Matthew Hale , James Fairbanks