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Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Hyperspectral imagery (HSI) one-class classification is aimed at identifying a single target class from the HSI by using only knowing positive data, which can significantly reduce the requirements for annotation. However, when one-class…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Hengwei Zhao , Yanfei Zhong , Xinyu Wang , Hong Shu

Endoscopy serves as an essential procedure for evaluating the gastrointestinal (GI) tract and plays a pivotal role in identifying GI-related disorders. Recent advancements in deep learning have demonstrated substantial progress in detecting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Astitva Kamble , Vani Bandodkar , Saakshi Dharmadhikary , Veena Anand , Pradyut Kumar Sanki , Mei X. Wu , Biswabandhu Jana

Traditional classifiers treat all labels as mutually independent, thereby considering all negative classes to be equally incorrect. This approach fails severely in many real-world scenarios, where a known semantic hierarchy defines a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Depanshu Sani , Saket Anand

Deploying deep neural networks for risk-sensitive tasks necessitates an uncertainty estimation mechanism. This paper introduces hierarchical selective classification, extending selective classification to a hierarchical setting. Our…

Machine Learning · Computer Science 2025-01-07 Shani Goren , Ido Galil , Ran El-Yaniv

Cell detection, segmentation and classification are essential for analyzing tumor microenvironments (TME) on hematoxylin and eosin (H&E) slides. Existing methods suffer from poor performance on understudied cell types (rare or not present…

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu

We present a novel diffusion-based approach to generate synthetic histopathological Whole Slide Images (WSIs) at an unprecedented gigapixel scale. Synthetic WSIs have many potential applications: They can augment training datasets to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Robert Harb , Thomas Pock , Heimo Müller

In modern cancer diagnostics, Whole Slide Imaging (WSI) is widely used to digitize tissue specimens for detailed, high-resolution examination; however, other diagnostic approaches, such as liquid biopsy and molecular testing, are also…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Seyed Kahaki , Alexander R. Webber , Ghada Zamzmi , Adarsh Subbaswamy , Rucha Deshpande , Aldo Badano

To train a robust deep learning model, one usually needs a balanced set of categories in the training data. The data acquired in a medical domain, however, frequently contains an abundance of healthy patients, versus a small variety of…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Jevgenij Gamper , Brandon Chan , Yee Wah Tsang , David Snead , Nasir Rajpoot

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

Hyperspectral image (HSI) classification is an important task in many applications, such as environmental monitoring, medical imaging, and land use/land cover (LULC) classification. Due to the significant amount of spectral information from…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Sertac Kilickaya , Mete Ahishali , Fahad Sohrab , Turker Ince , Moncef Gabbouj

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu