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Osteosarcoma (OS) is an aggressive primary bone malignancy. Accurate histopathological assessment of viable versus non-viable tumor regions after neoadjuvant chemotherapy is critical for prognosis and treatment planning, yet manual…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yaxi Chen , Zi Ye , Shaheer U. Saeed , Oliver Yu , Simin Ni , Jie Huang , Yipeng Hu

Whole Slide Image (WSI) analysis, with its ability to reveal detailed tissue structures in magnified views, plays a crucial role in cancer diagnosis and prognosis. Due to their giga-sized nature, WSIs require substantial storage and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Doanh Cao Bui , Jin Tae Kwak

This paper demonstrates a self-supervised framework for learning voxel-wise coarse-to-fine representations tailored for dense downstream tasks. Our approach stems from the observation that existing methods for hierarchical representation…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Eytan Kats , Jochen G. Hirsch , Mattias P. Heinrich

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

The advancement of digital pathology, particularly through computational analysis of whole slide images (WSI), is poised to significantly enhance diagnostic precision and efficiency. However, the large size and complexity of WSIs make it…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Ravi Kant Gupta , Dadi Dharani , Shambhavi Shanker , Amit Sethi

The use of Deep Learning (DL) based methods in medical histopathology images have been one of the most sought after solutions to classify, segment, and detect diseased biopsy samples. However, given the complex nature of medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Suvidha Tripathi , Satish Kumar Singh

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

Primary liver malignancies are widely recognized as the most heterogeneous and prognostically diverse cancers of the digestive system. Among these, hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) emerge as the two…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Anwen Lu , Mingxin Liu , Yiping Jiao , Hongyi Gong , Geyang Xu , Jun Chen , Jun Xu

Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Enhui Chai , Sicheng Chen , Tianyi Zhang , Chad Wong , Kecheng Huang , Zeyu Liu , Fei Xia

The structural and spatial arrangements of cells within tissues represent their functional states, making graph-based learning highly suitable for histopathology image analysis. Existing methods often rely on fixed graphs with predefined…

Image and Video Processing · Electrical Eng. & Systems 2025-10-16 Sudipta Paul , Amanda W. Lund , George Jour , Iman Osman , Bülent Yener

A method for active learning of hyperspectral images (HSI) is proposed, which combines deep learning with diffusion processes on graphs. A deep variational autoencoder extracts smoothed, denoised features from a high-dimensional HSI, which…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Abiy Tasissa , Duc Nguyen , James Murphy

In this paper, we propose a novel method for highly efficient follicular segmentation of thyroid cytopathological WSIs. Firstly, we propose a hybrid segmentation architecture, which integrates a classifier into Deeplab V3 by adding a…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Siyan Tao , Yao Guo , Chuang Zhu , Huang Chen , Yue Zhang , Jie Yang , Jun Liu

Hyperspectral image (HSI) classification is a cornerstone of remote sensing, enabling precise material and land-cover identification through rich spectral information. While deep learning has driven significant progress in this task, small…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Weilian Zhou , Weixuan Xie , Sei-ichiro Kamata , Man Sing Wong , Huiying , Hou , Haipeng Wang

Semi-supervised learning approaches have emerged as an active area of research to combat the challenge of obtaining large amounts of annotated data. Towards the goal of improving the performance of semi-supervised learning methods, we…

Computer Vision and Pattern Recognition · Computer Science 2021-12-22 Ashima Garg , Shaurya Bagga , Yashvardhan Singh , Saket Anand

Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment selection and patient survival, and pathological examination…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ying Xiao , Shimiao Tang , Xitong Ling , Weiming Chen , Jun Wang , Jiawen Li , Huaitian Yuan , Jianghui Yang , Bowen Li , Huan Li , Yiting Meng , Tian Guan , Yonghong He , Hongfang Yin

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Accurate diagnosis of pediatric brain tumors, starting with histopathology, presents unique challenges for deep learning, including severe data scarcity, class imbalance, and fine-grained morphologic overlap across diagnostically distinct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Joakim Nguyen , Jian Yu , Jinrui Fang , Nicholas Konz , Tianlong Chen , Sanjay Krishnan , Chandra Krishnan , Ying Ding , Hairong Wang , Ankita Shukla

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Haoming Luo , Xiaotian Yu , Shengxuming Zhang , Jiabin Xia , Yang Jian , Yuning Sun , Liang Xue , Mingli Song , Jing Zhang , Xiuming Zhang , Zunlei Feng

Histological classification of colorectal polyps plays a critical role in both screening for colorectal cancer and care of affected patients. An accurate and automated algorithm for the classification of colorectal polyps on digitized…

Hyperspectral image (HSI) classification techniques have been intensively studied and a variety of models have been developed. However, these HSI classification models are confined to pocket models and unrealistic ways of dataset…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Quanwei Liu , Yanni Dong , Tao Huang , Lefei Zhang , Bo Du
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