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Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited. Existing benchmarks often rely on static datasets or…

Computation and Language · Computer Science 2026-05-29 Valentina Bui Muti , Eugénie Dulout , Ziquan Fu

Clinical decision-making increasingly relies on timely and context-aware access to patient information within Electronic Health Records (EHRs), yet most existing natural language question-answering (QA) systems are evaluated solely on…

Existing question answering (QA) datasets derived from electronic health records (EHR) are artificially generated and consequently fail to capture realistic physician information needs. We present Discharge Summary Clinical Questions…

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack…

Machine Learning · Computer Science 2026-04-27 Hojjat Karami , David Atienza , Jean-Philippe Thiran , Anisoara Ionescu

One of the challenges in large-scale information retrieval (IR) is to develop fine-grained and domain-specific methods to answer natural language questions. Despite the availability of numerous sources and datasets for answer retrieval,…

Computation and Language · Computer Science 2019-11-28 Asma Ben Abacha , Dina Demner-Fushman

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Automated question answering (QA) over electronic health records (EHRs) demands precise evidence retrieval, faithful answer generation, and explicit grounding of answers in clinical notes. In this work, we present Neural1.5, our method for…

Computation and Language · Computer Science 2026-05-12 Abrar Majeedi , Viswanatha Reddy Gajjala , Sai Prasanna Teja Reddy Bogireddy , Siddhant Rai

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Medical question-answering benchmarks predominantly evaluate single-turn exchanges, failing to capture the iterative, clarification-seeking nature of real patient consultations. We introduce ThReadMed-QA, a benchmark of 2,437 fully-answered…

Computation and Language · Computer Science 2026-03-13 Monica Munnangi , Saiph Savage

There is a lack of benchmarks for evaluating large language models (LLMs) in long-form medical question answering (QA). Most existing medical QA evaluation benchmarks focus on automatic metrics and multiple-choice questions. While valuable,…

Computation and Language · Computer Science 2024-11-21 Pedram Hosseini , Jessica M. Sin , Bing Ren , Bryceton G. Thomas , Elnaz Nouri , Ali Farahanchi , Saeed Hassanpour

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Electronic Health Records (EHRs) are relational databases that store the entire medical histories of patients within hospitals. They record numerous aspects of patients' medical care, from hospital admission and diagnosis to treatment and…

Computation and Language · Computer Science 2024-05-24 Gyubok Lee , Sunjun Kweon , Seongsu Bae , Edward Choi

Ensuring the accuracy of responses provided by large language models (LLMs) is crucial, particularly in clinical settings where incorrect information may directly impact patient health. To address this challenge, we construct K-QA, a…

Computation and Language · Computer Science 2024-01-29 Itay Manes , Naama Ronn , David Cohen , Ran Ilan Ber , Zehavi Horowitz-Kugler , Gabriel Stanovsky

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Electronic health records (EHRs) are stored in various database systems with different database models on heterogeneous storage architectures, such as relational databases, document stores, or graph databases. These different database…

Databases · Computer Science 2024-11-15 Sithursan Sivasubramaniam , Cedric Osei-Akoto , Yi Zhang , Kurt Stockinger , Jonathan Fuerst

This thesis work falls within the framework of question answering (QA) in the biomedical domain where several specific challenges are addressed, such as specialized lexicons and terminologies, the types of treated questions, and the…

Computation and Language · Computer Science 2023-07-26 Mourad Sarrouti

We introduce a novel question-answering (QA) dataset using echocardiogram reports sourced from the Medical Information Mart for Intensive Care database. This dataset is specifically designed to enhance QA systems in cardiology, consisting…

Artificial Intelligence · Computer Science 2025-03-07 Lama Moukheiber , Mira Moukheiber , Dana Moukheiiber , Jae-Woo Ju , Hyung-Chul Lee

Pre-consultation is a critical component of effective healthcare delivery. However, generating comprehensive pre-consultation questionnaires from complex, voluminous Electronic Medical Records (EMRs) is a challenging task. Direct Large…

Artificial Intelligence · Computer Science 2025-08-04 Ruiqing Ding , Qianfang Sun , Yongkang Leng , Hui Yin , Xiaojian Li