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Deep learning models have shown promise in lung pathology detection from chest X-rays, but widespread clinical adoption remains limited due to opaque model decision-making. In prior work, we introduced ClinicXAI, a human-centric,…

Artificial Intelligence · Computer Science 2026-04-17 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Recent research has supported that system explainability improves user trust and willingness to use medical AI for diagnostic support. In this paper, we use chest disease diagnosis based on X-Ray images as a case study to investigate user…

Human-Computer Interaction · Computer Science 2022-04-27 Yao Rong , Nora Castner , Efe Bozkir , Enkelejda Kasneci

Large language models (LLMs) enable waveform-to-text ECG interpretation and interactive clinical questioning, yet most ECG-LLM systems still rely on weak signal-text alignment and retrieval without explicit physiological or causal…

Recent multimodal LLMs have shown promise in chart-based visual question answering, but their performance declines sharply on unannotated charts-those requiring precise visual interpretation rather than relying on textual shortcuts. To…

Artificial Intelligence · Computer Science 2026-01-08 Rachneet Kaur , Nishan Srishankar , Zhen Zeng , Sumitra Ganesh , Manuela Veloso

Ultrasound interpretation requires both precise lesion localization and holistic clinical reasoning, yet existing methods typically excel at only one of these capabilities: specialized detectors offer strong localization but limited…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Jing Zhang , Wentao Jiang , Tao Huang , Zhiwei Wang , Jianxin Liu , Jian Chen , Ping Ye , Gang Wang , Zengmao Wang , Bo Du , Dacheng Tao

Concept Bottleneck Models (CBMs) in medical imaging aim to improve model interpretability by predicting intermediate clinical concepts before final diagnoses. However, most existing CBMs treat concepts as discriminative predictors of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

Multimodal models trained on large natural image-text pair datasets have exhibited astounding abilities in generating high-quality images. Medical imaging data is fundamentally different to natural images, and the language used to…

Test-time scaling offers a promising way to improve the reasoning performance of vision-language large models (VLLMs) without additional training. In this paper, we explore a simple but effective approach for applying test-time scaling to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Yue Yao , Zelin Wen , Yan Tong , Xinyu Tian , Xuqing Li , Xiao Ma , Dongliang Xu , Tom Gedeon

Inspired by the success of large language models (LLMs), there is growing research interest in developing LLMs in the medical domain to assist clinicians. However, for hospitals, using closed-source commercial LLMs involves privacy issues,…

Machine Learning · Computer Science 2024-09-23 Jinge Wu , Yunsoo Kim , Daqian Shi , David Cliffton , Fenglin Liu , Honghan Wu

Vision-language pretraining has advanced image-text alignment, yet progress in radiology remains constrained by the heterogeneity of clinical reports, including abbreviations, impression-only notes, and stylistic variability. Unlike…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Hanbin Ko , Gihun Cho , Inhyeok Baek , Donguk Kim , Joonbeom Koo , Changi Kim , Dongheon Lee , Chang Min Park

Despite recent advances in video understanding, the capabilities of Large Video Language Models (LVLMs) to perform video-based causal reasoning remains underexplored, largely due to the absence of relevant and dedicated benchmarks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Pritam Sarkar , Ali Etemad

Multimodal large language models (MLLMs) that integrate visual and textual reasoning leverage chain-of-thought (CoT) prompting to tackle complex visual tasks, yet continue to exhibit visual hallucinations and an over-reliance on textual…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Jing Bi , Guangyu Sun , Ali Vosoughi , Chen Chen , Chenliang Xu

Chest X-ray (CXR) is the most frequently ordered imaging test, supporting diverse clinical tasks from thoracic disease detection to postoperative monitoring. However, task-specific classification models are limited in scope, require costly…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Zefan Yang , Xuanang Xu , Jiajin Zhang , Ge Wang , Mannudeep K. Kalra , Pingkun Yan

We present a Collaborative Agent-Based Framework for Multi-Image Reasoning. Our approach tackles the challenge of interleaved multimodal reasoning across diverse datasets and task formats by employing a dual-agent system: a language-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Angelos Vlachos , Giorgos Filandrianos , Maria Lymperaiou , Nikolaos Spanos , Ilias Mitsouras , Vasileios Karampinis , Athanasios Voulodimos

Large language models (LLMs) have recently showcased remarkable capabilities, spanning a wide range of tasks and applications, including those in the medical domain. Models like GPT-4 excel in medical question answering but may face…

Computation and Language · Computer Science 2025-07-02 Bowen Wang , Jiuyang Chang , Yiming Qian , Guoxin Chen , Junhao Chen , Zhouqiang Jiang , Jiahao Zhang , Yuta Nakashima , Hajime Nagahara

Computed Tomography (CT) scan, which produces 3D volumetric medical data that can be viewed as hundreds of cross-sectional images (a.k.a. slices), provides detailed anatomical information for diagnosis. For radiologists, creating CT…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Yuren Mao , Wenyi Xu , Yuyang Qin , Yunjun Gao

With the emergence of large-scale vision language models (VLM), it is now possible to produce realistic-looking radiology reports for chest X-ray images. However, their clinical translation has been hampered by the factual errors and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Razi Mahmood , Diego Machado-Reyes , Joy Wu , Parisa Kaviani , Ken C. L. Wong , Niharika D'Souza , Mannudeep Kalra , Ge Wang , Pingkun Yan , Tanveer Syeda-Mahmood

Large Language Models (LLMs) have shown promising performance in time series modeling tasks, but do they truly understand time series data? While multiple benchmarks have been proposed to answer this fundamental question, most are manually…

Artificial Intelligence · Computer Science 2026-04-15 Malgorzata Gwiazda , Yifu Cai , Mononito Goswami , Arjun Choudhry , Artur Dubrawski
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