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We present VinDr-CXR-VQA, a large-scale chest X-ray dataset for explainable Medical Visual Question Answering (Med-VQA) with spatial grounding. The dataset contains 17,597 question-answer pairs across 4,394 images, each annotated with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Dang H. Nguyen , Hieu H. Pham , Hao T. Nguyen , Hieu H. Pham

Vision-Language Models (VLMs) have demonstrated remarkable progress in multimodal understanding, yet their capabilities for scientific reasoning remain inadequately assessed. Current multimodal benchmarks predominantly evaluate generic…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Ai Jian , Weijie Qiu , Xiaokun Wang , Peiyu Wang , Yunzhuo Hao , Jiangbo Pei , Yichen Wei , Yi Peng , Xuchen Song

Vision-language models (VLMs) often produce chain-of-thought (CoT) explanations that sound plausible yet fail to reflect the underlying decision process, undermining trust in high-stakes clinical use. Existing evaluations rarely catch this…

Conversational AI tools that can generate and discuss clinically correct radiology reports for a given medical image have the potential to transform radiology. Such a human-in-the-loop radiology assistant could facilitate a collaborative…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Chantal Pellegrini , Ege Özsoy , Benjamin Busam , Nassir Navab , Matthias Keicher

Echocardiography plays an important role in the screening and diagnosis of cardiovascular diseases. However, automated intelligent analysis of echocardiographic data remains challenging due to complex cardiac dynamics and strong view…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Peng Huang , Yiming Wang , Yineng Chen , Liangqiao Gui , Hui Guo , Bo Peng , Shu Hu , Xi Wu , Tsao Connie , Hongtu Zhu , Balakrishnan Prabhakaran , Xin Wang

In this study, we present Colon-X, an open initiative aimed at advancing multimodal intelligence in colonoscopy. We begin by constructing ColonVQA, the most comprehensive multimodal dataset ever built for colonoscopy, featuring over 1.1M+…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ge-Peng Ji , Jingyi Liu , Deng-Ping Fan , Huazhu Fu , Nick Barnes

Precision therapeutics require multimodal adaptive models that generate personalized treatment recommendations. We introduce TxAgent, an AI agent that leverages multi-step reasoning and real-time biomedical knowledge retrieval across a…

Artificial Intelligence · Computer Science 2025-03-17 Shanghua Gao , Richard Zhu , Zhenglun Kong , Ayush Noori , Xiaorui Su , Curtis Ginder , Theodoros Tsiligkaridis , Marinka Zitnik

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Information Retrieval · Computer Science 2025-04-30 Hasan Md Tusfiqur Alam , Devansh Srivastav , Md Abdul Kadir , Daniel Sonntag

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

Recent advancements in multimodal Large Language Models (LLMs) have significantly enhanced the automation of medical image analysis, particularly in generating radiology reports from chest X-rays (CXR). However, these models still suffer…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yunsoo Kim , Jinge Wu , Su-Hwan Kim , Pardeep Vasudev , Jiashu Shen , Honghan Wu

Chest X-rays (CXRs) are the most frequently performed imaging examinations in clinical settings. Recent advancements in Large Multimodal Models (LMMs) have enabled automated CXR interpretation, enhancing diagnostic accuracy and efficiency.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Qingqiu Li , Zihang Cui , Seongsu Bae , Jilan Xu , Runtian Yuan , Yuejie Zhang , Rui Feng , Quanli Shen , Xiaobo Zhang , Junjun He , Shujun Wang

Despite the progress in automatic detection of radiologic findings from chest X-ray (CXR) images in recent years, a quantitative evaluation of the explainability of these models is hampered by the lack of locally labeled datasets for…

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Report generation models offer fine-grained textual interpretations of medical images like chest X-rays, yet they often lack interactivity (i.e. the ability to steer the generation process through user queries) and localized…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Philip Müller , Georgios Kaissis , Daniel Rueckert

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

The latest breakthroughs in large vision-language models, such as Bard and GPT-4, have showcased extraordinary abilities in performing a wide range of tasks. Such models are trained on massive datasets comprising billions of public…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Omkar Thawakar , Abdelrahman Shaker , Sahal Shaji Mullappilly , Hisham Cholakkal , Rao Muhammad Anwer , Salman Khan , Jorma Laaksonen , Fahad Shahbaz Khan

Chest X-ray (CXR) reporting follows a region-based clinical workflow in which radiologists inspect anatomical regions and integrate localized findings into a final report. However, existing resources for CXR report generation provide these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yichen Zhao , Zelin Peng , Fenghe Tang , Piao Yang , Yu Huang , Wei Shen

Medical Visual Language Models have shown great potential in various healthcare applications, including medical image captioning and diagnostic assistance. However, most existing models rely on text-based instructions, limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Tan-Hanh Pham , Chris Ngo , Trong-Duong Bui , Minh Luu Quang , Tan-Huong Pham , Truong-Son Hy

Current clinical agent built on small LLMs, such as TxAgent suffer from a \textit{Context Utilization Failure}, where models successfully retrieve biomedical evidence due to supervised finetuning but fail to ground their diagnosis in that…

Artificial Intelligence · Computer Science 2025-12-08 Ting-Ting Xie , Yixin Zhang

Despite significant advancements in Large Language Models (LLMs) and Large Vision-Language Models (LVLMs), current models still face substantial challenges in handling complex, multi-turn, and visually-grounded tasks that demand deep…

Computation and Language · Computer Science 2025-08-22 Seungmin Han , Haeun Kwon , Ji-jun Park , Taeyang Yoon