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Vocal health plays a crucial role in peoples' lives, significantly impacting their communicative abilities and interactions. However, despite the global prevalence of voice disorders, many lack access to convenient diagnosis and treatment.…

We present ReXVQA, the largest and most comprehensive benchmark for visual question answering (VQA) in chest radiology, comprising approximately 696,000 questions paired with 160,000 chest X-rays studies across training, validation, and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Ankit Pal , Jung-Oh Lee , Xiaoman Zhang , Malaikannan Sankarasubbu , Seunghyeon Roh , Won Jung Kim , Meesun Lee , Pranav Rajpurkar

Multimodal medical large language models have shown substantial progress in chest X-ray interpretation but continue to face challenges in spatial reasoning and anatomical understanding. Although existing grounding techniques improve overall…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Anees Ur Rehman Hashmi , Numan Saeed , Christoph Lippert

Large Language Models (LLMs) achieve competitive results compared to human experts in medical examinations. However, it remains a challenge to apply LLMs to complex clinical decision-making, which requires a deep understanding of medical…

As artificial intelligence (AI) becomes increasingly central to healthcare, the demand for explainable and trustworthy models is paramount. Current report generation systems for chest X-rays (CXR) often lack mechanisms for validating…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Sayeh Gholipour Picha , Dawood Al Chanti , Alice Caplier

Large language models (LLMs) have shown remarkable ability in various language tasks, especially with their emergent in-context learning capability. Extending LLMs to incorporate visual inputs, large vision-language models (LVLMs) have…

Machine Learning · Computer Science 2025-10-13 Aneesh Komanduri , Karuna Bhaila , Xintao Wu

In modern medicine, clinical diagnosis relies on the comprehensive analysis of primarily textual and visual data, drawing on medical expertise to ensure systematic and rigorous reasoning. Recent advances in large Vision-Language Models…

Artificial Intelligence · Computer Science 2025-07-03 Ziyue Wang , Junde Wu , Linghan Cai , Chang Han Low , Xihong Yang , Qiaxuan Li , Yueming Jin

Deep reasoning is fundamental for solving complex tasks, especially in vision-centric scenarios that demand sequential, multimodal understanding. However, existing benchmarks typically evaluate agents with fully synthetic, single-turn…

The rapid evolution of artificial intelligence, especially in large language models (LLMs), has significantly impacted various domains, including healthcare. In chest X-ray (CXR) analysis, previous studies have employed LLMs, but with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Jonggwon Park , Soobum Kim , Byungmu Yoon , Jihun Hyun , Kyoyun Choi

We present M-Reason, a demonstration system for transparent, agent-based reasoning and evidence integration in the biomedical domain, with a focus on cancer research. M-Reason leverages recent advances in large language models (LLMs) and…

Artificial Intelligence · Computer Science 2025-10-08 Oskar Wysocki , Magdalena Wysocka , Mauricio Jacobo , Harriet Unsworth , André Freitas

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive…

Recent advancements in Computer Assisted Diagnosis have shown promising performance in medical imaging tasks, particularly in chest X-ray analysis. However, the interaction between these models and radiologists has been primarily limited to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Yue Gao , Honghan Wu

Large language models (LLMs) and agentic systems have shown promise for clinical decision support, but existing works largely assume that evidence has already been curated and handed to the model. Real-world clinical workflows instead…

Computation and Language · Computer Science 2026-05-20 Juncheng Wu , Letian Zhang , Yuhan Wang , Haoqin Tu , Hardy Chen , Zijun Wang , Cihang Xie , Yuyin Zhou

Chest radiograph interpretation requires temporal reasoning over prior and current studies, yet most vision-language models are trained on static image-report pairs and lack explicit supervision for modeling longitudinal change. We…

General-purpose large Vision-Language Models (VLMs) demonstrate strong capabilities in generating detailed descriptions for natural images. However, their performance in the medical domain remains suboptimal, even for relatively…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Yifan Li , Fenghe Tang , Yingtai Li , Shaohua Kevin Zhou

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Purpose: This study aimed to develop an open-source multimodal large language model (CXR-LLAVA) for interpreting chest X-ray images (CXRs), leveraging recent advances in large language models (LLMs) to potentially replicate the image…

Computation and Language · Computer Science 2024-01-17 Seowoo Lee , Jiwon Youn , Hyungjin Kim , Mansu Kim , Soon Ho Yoon

AI agents with tool-use capabilities show promise for integrating the domain expertise of various tools. In the medical field, however, tools are usually AI models that are inherently error-prone and can produce contradictory responses.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Zheang Huai , Honglong Yang , Xiaomeng Li

Vision-Language Models (VLMs) show promise in medical diagnosis, yet suffer from reasoning detachment, where linguistically fluent explanations drift from verifiable image evidence, undermining clinical trust. Recent multi-agent frameworks…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Qianhan Feng , Zhongzhen Huang , Yakun Zhu , Xiaofan Zhang , Qi Dou

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

Artificial Intelligence · Computer Science 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu