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We analyze a class of general nonlinear epidemic models with age and space structure, including a nonlocal infection term depending on age and space. After establishing the well-posedness of the state partial differential equation, we…

Optimization and Control · Mathematics 2025-03-11 Behzad Azmi , Nicolas Schlosser

Dengue fever poses a persistent public health challenge in rapidly urbanizing Indian cities such as Ahmedabad, where spatial heterogeneity and seasonal variability complicate forecasting and control. In this study, we develop a data-driven…

Populations and Evolution · Quantitative Biology 2026-05-19 Sourav Roy , Rajendra Gadhavi , Bhavin Solanki , Chirag Shah , Raj C. Sharma , Indrajit Ghosh

Aedes Aegypti is the vector of several deadly diseases, including Zika. Effective and sustainable vector control measures must be deployed to keep A. aegypti numbers under control. The distribution of A. Aegypti is subject to spatial and…

Populations and Evolution · Quantitative Biology 2016-08-05 Chathika Gunaratne , Mustafa Ilhan Akbas , Ivan Garibay , Ozlem Ozmen

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

The dynamics of strongly immunizing childhood infections is still not well understood. Although reports of successful modeling of several incidence data records can be found in the literature, the key determinants of the observed temporal…

Populations and Evolution · Quantitative Biology 2012-10-09 Ganna Rozhnova , Ana Nunes

Voluntary vaccination is essential to protect oneself from infection and suppress the spread of infectious diseases. Voluntary vaccination behavior is influenced by factors such as age and interaction patterns. Differences in health…

Physics and Society · Physics 2024-12-11 Yanyi Nie , Tao Lin , Yanbing Liu , Wei Wang

Over 50% of the world population is at risk of mosquito-borne diseases. Female Ae. aegypti mosquito species transmit Zika, Dengue, and Chikungunya. The spread of these diseases correlate positively with the vector population, and this…

Populations and Evolution · Quantitative Biology 2019-11-28 Oladimeji Mudele , Fabio M. Bayer , Lucas Zanandrez , Alvaro E. Eiras , Paolo Gamba

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

Vector-borne diseases arise from the coupled dynamics of human mobility and mosquito ecology, producing outbreaks shaped by both spatial distributions and temporal patterns of movement. Here we develop a coarse-grained hub--leaf reduction…

Populations and Evolution · Quantitative Biology 2025-08-29 Bibandhan Poudyal , Gourab Ghoshal

Vector-borne diseases with reservoir cycles are complex to understand because new infections come from contacts of the vector with humans and different reservoirs. In this scenario, the basic reproductive number $\mathcal{R}^h_0$ of the…

Populations and Evolution · Quantitative Biology 2017-02-10 Esteban Vargas , Camilo Sanabria

The contact structure of a population plays an important role in transmission of infection. Many ``structured models'' capture aspects of the contact structure through an underlying network or a mixing matrix. An important observation in…

Populations and Evolution · Quantitative Biology 2020-07-15 Francesco Di Lauro , Luc Berthouze , Matthew D. Dorey , Joel C. Miller , István Z. Kiss

Seasonal influenza presents an ongoing challenge to public health. The rapid evolution of the flu virus necessitates annual vaccination campaigns, but the decision to get vaccinated or not in a given year is largely voluntary, at least in…

Populations and Evolution · Quantitative Biology 2021-01-21 Irena Papst , Kevin P. O'Keeffe , Steven H. Strogatz

We present an application of optimal control theory to Dengue epidemics. This epidemiologic disease is an important theme in tropical countries due to the growing number of infected individuals. The dynamic model is described by a set of…

Optimization and Control · Mathematics 2010-08-27 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

A new age-distributed immuno-epidemiological model with information-based vaccine uptake suggested in this work represents a system of integro-differential equations for the numbers of susceptible individuals, infected individuals,…

Populations and Evolution · Quantitative Biology 2024-04-02 Samiran Ghosh , Malay Banerjee , Vitaly Volpert

Even as the incidence of mosquito-borne diseases like West Nile Virus (WNV) in North America has risen over the past decade, effectively modelling mosquito population density or, the abundance has proven to be a persistent challenge. It is…

Populations and Evolution · Quantitative Biology 2024-09-19 Suman Bhowmick , Patrick Irwin , Kristina Lopez , Megan Lindsay Fritz , Rebecca Lee Smith

In face of climate change and increasing urbanization, the predictive mosquito-borne diseases (MBD) transmission models require constant updates. Thus, is urgent to comprehend the driving forces of this non stationary behavior, observed…

Quantitative Methods · Quantitative Biology 2024-11-22 Marcio Maciel Bastos , Luiz Max Carvalho , Eduardo Correa Araujo , Flávio Codeço Coelho

During the last decades, the global prevalence of dengue progressed dramatically. It is a disease which is now endemic in more than one hundred countries of Africa, America, Asia and the Western Pacific. This study addresses a mathematical…

This paper presents an age-structured, non-autonomous logistic model describing the aquatic and adult stages of the dynamics of malaria-vector mosquitoes. We propose a biological control strategy targeting the aquatic compartment and…

Analysis of PDEs · Mathematics 2025-11-18 Marius Bargo , Yacouba Simpore

Controlling diseases such as dengue fever, chikungunya and zika fever by introduction of the intracellular parasitic bacterium Wolbachia in mosquito populations which are their vectors, is presently quite a promising tool to reduce their…

Optimization and Control · Mathematics 2019-03-05 Pierre-Alexandre Bliman