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In mathematical epidemiology, epidemic control often aims at driving the number of infected individuals to zero, asymptotically. However , during the transitory phase, the number of infected can peak at high values. In this paper, we…

Optimization and Control · Mathematics 2015-10-06 Michel De Lara , Lilian Sofia Sepulveda Salcedo

Mosquitoes are vectors of viral diseases with epidemic potential in many regions of the world, and in absence of vaccines or therapies, their control is the main alternative. Chemical control through insecticides has been one of the…

Populations and Evolution · Quantitative Biology 2021-04-07 Pastor Pérez Estigarribia , Pierre-Alexandre Bliman , Christian Schaerer

As offered by the World Health Organisation (WHO), close to half of the population in the world's resides in dengue-risk zones. Dengue viruses are transmitted to individuals by Aedes mosquito species infected bite (Ae. Albopictus of Ae.…

Populations and Evolution · Quantitative Biology 2025-03-12 Burcu Gürbüz , Aytül Gökçe , Segun I. Oke , Michael O. Adeniyi , Mayowa M. Ojo

We propose a mathematical model to investigate the effects of information-dependent vaccination behavior on meningitis transmission. The information is represented by means of information index as early proposed in (d'Onofrio et al., Theor.…

Populations and Evolution · Quantitative Biology 2020-05-26 Bruno Buonomo , Alberto d'Onofrio , Semu Mitiku Kassa , Yetwale Hailu Workineh

Urbanization drives the epidemiology of infectious diseases to many threats and new challenges. In this research, we study the interplay between human mobility and dengue outbreaks in the complex urban environment of the city-state of…

Populations and Evolution · Quantitative Biology 2019-10-09 Emanuele Massaro , Daniel Kondor , Carlo Ratti

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

It is preliminarily known that Aedes mosquitoes are very close to humans and their dwellings, also give rises to a broad spectrum of diseases: dengue, yellow fever, chikungunya. In this paper, we explore a multi-age-class model for mosquito…

Optimization and Control · Mathematics 2017-12-04 Karunia Putra Wijaya , Thomas Goetz , Edy Soewono

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

Quantitative Methods · Quantitative Biology 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

Vector-borne epidemics are the result of the combination of different factors such as the crossed contagions between humans and vectors, their demographic distribution and human mobility among others. The current availability of information…

In this work we explore the effects of human mobility on the dispersion of a vector borne disease. We combine an already presented stochastic model for dengue with a simple representation of the daily motion of humans on a schematic city of…

Populations and Evolution · Quantitative Biology 2015-05-27 Daniel H Barmak , Claudio O Dorso , Marcelo Otero , Hernán G Solari

Capturing the structure of a population and characterising contacts within the population are key to reliable projections of infectious disease. Two main elements of population structure -- contact heterogeneity and age -- have been…

Physics and Society · Physics 2025-03-17 Luke Murray Kearney , Emma L. Davis , Matt J. Keeling

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

In diseases with long-term immunity, vaccination is known to increase the average age at infection as a result of the decrease in the pathogen circulation. This implies that a vaccination campaign can have negative effects when a disease is…

Populations and Evolution · Quantitative Biology 2024-06-04 Fabio A. C. C. Chalub , Paulo Doutor , Paula Patrício , Maria do Céu Soares

A cholera transmission model incorporating water-borne and horizontal transmissions as well as infectivity of deceased individuals is formulated and studied. The model also describes an imperfect and waning vaccination. Global stability of…

Populations and Evolution · Quantitative Biology 2025-04-11 Abdramane Annour Saad , Julien Arino , Patrick M Tchepmo Djomegni , Mahamat S Daoussa Haggar

This study presents a seasonally forced cholera model that incorporates imperfect vaccination as a control strategy. The model captures the temporal dynamics of susceptible, vaccinated, infected, and recovered individuals, as well as the…

Populations and Evolution · Quantitative Biology 2025-07-15 Eric Herrison Gyamfi

Dengue and Zika incidence data and the latest research have raised questions about how dengue vaccine strategies might be impacted by the emergence of Zika virus. Existing antibodies to one virus might temporarily protect or promote…

Populations and Evolution · Quantitative Biology 2023-03-14 Lorena C. Bulhosa , Juliane F. Oliveira

As the development of a dengue vaccine is ongoing, we simulate an hypothetical vaccine as an extra protection to the population. In a first phase, the vaccination process is studied as a new compartment in the model, and different ways of…

Optimization and Control · Mathematics 2013-11-26 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

The success of an infectious disease to invade a population is strongly controlled by the population's specific connectivity structure. Here a network model is presented as an aid in understanding the role of social behavior and…

Cellular Automata and Lattice Gases · Physics 2007-07-10 Anna Litvak-Hinenzon , Lewi Stone

A multi-patch and multi-group modeling framework describing the dynamics of a class of diseases driven by the interactions between vectors and hosts structured by groups is formulated. Hosts' dispersal is modeled in terms of patch-residence…

Populations and Evolution · Quantitative Biology 2017-03-16 Derdei Bichara , Carlos Castillo-Chavez