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Organoids are multi-cellular structures which are cultured in vitro from stem cells to resemble specific organs (e.g., brain, liver) in their three-dimensional composition. Dynamic changes in the shape and composition of these model systems…

Quantitative Methods · Quantitative Biology 2022-12-23 Lewis Marsh , Felix Y. Zhou , Xiao Qin , Xin Lu , Helen M. Byrne , Heather A. Harrington

The Euler Characteristic Transform (ECT) has proven to be a powerful representation, combining geometrical and topological characteristics of shapes and graphs. However, the ECT was hitherto unable to learn task-specific representations. We…

Machine Learning · Computer Science 2024-03-20 Ernst Roell , Bastian Rieck

The Euler characteristic transform (ECT) is a simple to define yet powerful representation of shape. The idea is to encode an embedded shape using sub-level sets of a a function defined based on a given direction, and then returning the…

Computational Geometry · Computer Science 2023-10-17 Elizabeth Munch

The Euler characteristic transform (ECT) is a signature from topological data analysis (TDA) which summarises shapes embedded in Euclidean space. Compared with other TDA methods, the ECT is fast to compute and it is a sufficient statistic…

Statistics Theory · Mathematics 2023-03-24 Lewis Marsh , David Beers

Datasets are mathematical objects (e.g., point clouds, matrices, graphs, images, fields/functions) that have shape. This shape encodes important knowledge about the system under study. Topology is an area of mathematics that provides…

Algebraic Topology · Mathematics 2021-09-09 Alexander Smith , Victor Zavala

The shape of a molecule determines its physicochemical and biological properties. However, it is often underrepresented in standard molecular representation learning approaches. Here, we propose using the Euler Characteristic Transform…

Machine Learning · Computer Science 2025-07-08 Victor Toscano-Duran , Florian Rottach , Bastian Rieck

The Euler Characteristic Transform (ECT) is a robust method for shape classification. It takes an embedded shape and, for each direction, computes a piecewise constant function representing the Euler Characteristic of the shape's sublevel…

Computational Geometry · Computer Science 2025-06-26 Jasmine George , Oscar Lledo Osborn , Elizabeth Munch , Messiah Ridgley , Elena Xinyi Wang

Given a definable function $f: S \to \mathbb{R}$ on a definable set $S$, we study sublevel sets of the form $S^f_t \coloneqq \{x \in S: f(x) \leq t\}$ for all $t \in \mathbb{R}$. Using o-minimal structures, we prove that the Euler…

Algebraic Topology · Mathematics 2026-03-27 Mattie Ji , Kun Meng

In this article, we study Euler characteristic techniques in topological data analysis. Pointwise computing the Euler characteristic of a family of simplicial complexes built from data gives rise to the so-called Euler characteristic…

Machine Learning · Computer Science 2024-07-25 Olympio Hacquard , Vadim Lebovici

The Euler Characteristic Transform (ECT) is an efficiently-computable geometrical-topological invariant that characterizes the global shape of data. In this paper, we introduce the Local Euler Characteristic Transform ($\ell$-ECT), a novel…

Machine Learning · Computer Science 2025-05-29 Julius von Rohrscheidt , Bastian Rieck

The Euler Characteristic Transform (ECT) of Turner et al. provides a way to statistically analyze non-diffeomorphic shapes without relying on landmarks. In applications, this transform is typically approximated by a discrete set of…

Algebraic Topology · Mathematics 2024-11-14 Henry Kirveslahti , Xiaohan Wang

This overview article makes the case for how topological concepts can enrich research in machine learning. Using the Euler Characteristic Transform (ECT), a geometrical-topological invariant, as a running example, I present different use…

Machine Learning · Computer Science 2026-01-16 Bastian Rieck

The Euler characteristic (EC) is a powerful topological descriptor that can be used to quantify the shape of data objects that are represented as fields/manifolds. Fast methods for computing the EC are required to enable processing of…

Computational Geometry · Computer Science 2024-04-26 Daniel J. Laky , Victor M. Zavala

Tools of Topological Data Analysis provide stable summaries encapsulating the shape of the considered data. Persistent homology, the most standard and well studied data summary, suffers a number of limitations; its computations are hard to…

Algebraic Topology · Mathematics 2023-11-21 Paweł Dłotko , Davide Gurnari

The Euler characteristic transform (ECT) is an integral transform used widely in topological data analysis. Previous efforts by Curry et al. and Ghrist et al. have independently shown that the ECT is injective on all compact definable sets.…

Computational Geometry · Computer Science 2024-05-22 Mattie Ji

We present Euler Characteristic Surfaces as a multiscale spatiotemporal topological summary of time series data encapsulating the topology of the system at different time instants and length scales. Euler Characteristic Surfaces with an…

Other Condensed Matter · Physics 2024-08-20 Anamika Roy , Atish J. Mitra , Tapati Dutta

We study the use of the Euler characteristic for multiparameter topological data analysis. Euler characteristic is a classical, well-understood topological invariant that has appeared in numerous applications, including in the context of…

Algebraic Topology · Mathematics 2021-02-17 Gabriele Beltramo , Rayna Andreeva , Ylenia Giarratano , Miguel O. Bernabeu , Rik Sarkar , Primoz Skraba

Symmetries play a crucial role in the classification of topological phases of matter. Although recent studies have established a powerful framework to search for and classify topological phases based on symmetry indicators, there exists a…

Quantum Physics · Physics 2022-10-11 W. -D. Zhao , Y. -B. Yang , Y. Jiang , Z. -C. Mao , W. -X. Guo , L. -Y. Qiu , G. -X. Wang , L. Yao , L. He , Z. -C. Zhou , Y. Xu , L. -M. Duan

Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be understood and…

Other Quantitative Biology · Quantitative Biology 2020-08-21 Tamàs Fülöp , Mathieu Desroches , Fernando Antônio Nóbrega Santos , Serafim Rodrigues

Persistent homology (PH) -- the conventional method in topological data analysis -- is computationally expensive, requires further vectorization of its signatures before machine learning (ML) can be applied, and captures information along…

Machine Learning · Computer Science 2026-03-17 Salam Rabindrajit Luwang , Sushovan Majhi , Vishal Mandal , Atish J. Mitra , Md. Nurujjaman , Buddha Nath Sharma
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