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The understanding of toxicity is of paramount importance to human health and environmental protection. Quantitative toxicity analysis has become a new standard in the field. This work introduces element specific persistent homology (ESPH),…

Quantitative Methods · Quantitative Biology 2017-12-13 Kedi Wu , Guo-Wei Wei

The statistical analysis of marked point processes requires disentangling complex spatial arrangements from attribute-dependent interactions. While classical summary statistics are effective for second-order dependencies, they frequently…

Methodology · Statistics 2026-05-15 Matthias Eckardt , Mehdi Moradi

Parameter-efficient fine-tuning (PEFT) has emerged as a promising paradigm for adapting pretrained models under limited data conditions. However, most existing PEFT methods are designed for matrix-structured parameters and are not well…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Guanghua He , Hancan Zhu , Gaohang Yu , An Zhang

A primary hypothesis that drives scientific and engineering studies is that data has structure. The dominant paradigms for describing such structure are statistics (e.g., moments, correlation functions) and signal processing (e.g.,…

Algebraic Topology · Mathematics 2020-11-11 Alexander D. Smith , Pawel Dlotko , Victor M. Zavala

Advancements in artificial intelligence (AI) are transforming pathology by integrat-ing large language models (LLMs) with retrieval-augmented generation (RAG) and domain-specific foundation models. This study explores the application of…

Computation and Language · Computer Science 2025-05-14 Hussien Al-Asi , Jordan P Reynolds , Shweta Agarwal , Bryan J Dangott , Aziza Nassar , Zeynettin Akkus

Objective: Time-difference electrical impedance tomography (EIT) is gaining widespread use for bedside lung monitoring in intensive care patients suffering from lung-related diseases. It involves collecting voltage measurements from…

Skin, the primary regulator of heat exchange, relies on sweat glands for thermoregulation. Alterations in sweat gland morphology play a crucial role in various pathological conditions and clinical diagnoses. Current methods for observing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Shaoyu Pei , Renxiong Wu , Hao Zheng , Lang Qin , Shuaichen Lin , Yuxing Gan , Wenjing Huang , Zhixuan Wang , Mohan Qin , Yong Liu , Guangming Ni

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

Accurate segmentation of tubular topological structures (e.g., fissures and vasculature) is critical in various fields to guarantee dependable downstream quantitative analysis and modeling. However, in dense prediction tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Yiqi Chen , Ganghai Huang , Sheng Zhang , Jianglin Dai

Aggregates of misfolded tau proteins (or just 'tau' for brevity) play a crucial role in the progression of Alzheimer's disease (AD) as they correlate with cell death and accelerated tissue atrophy. Longitudinal positron emission tomography…

Quantitative Methods · Quantitative Biology 2020-12-08 Klaudius Scheufele , Shashank Subramanian , George Biros

Creating comprehensible visualizations of highly overlapping set-typed data is a challenging task due to its complexity. To facilitate insights into set connectivity and to leverage semantic relations between intersections, we propose a…

Data Structures and Algorithms · Computer Science 2021-08-10 Rebecca Kehlbeck , Jochen Görtler , Yunhai Wang , Oliver Deussen

Magnetic resonance imaging (MRI) based electrical properties tomography (EPT) is the quantification of the conductivity and permittivity of different tissues. These electrical properties can be obtained through different reconstruction…

Time dependence is a universal phenomenon in nature, and a variety of mathematical models in terms of dynamical systems have been developed to understand the time-dependent behavior of real-world problems. Originally constructed to analyze…

Algebraic Topology · Mathematics 2018-02-14 Zixuan Cang , Elizabeth Munch , Guo-Wei Wei

In cardiac cells, structural organization is an important indicator of cell maturity and healthy function. Healthy cardiomyocytes exhibit well-aligned morphology with densely packed and organized sarcomeres. Immature or diseased…

Quantitative Methods · Quantitative Biology 2025-02-03 Saeed Mohammadzadeh , Emma Lejeune

The past decades have witnessed a transformation in characterizing condensed matter systems with topology. Aided by a refined understanding of topological band structures with crystalline symmetries that has emerged recently, many…

Materials Science · Physics 2021-10-12 Lin-Lin Wang , Hoi Chun Po , Robert-Jan Slager , Ashvin Vishwanath

Integrating prior knowledge of neurophysiology into neural network architecture enhances the performance of emotion decoding. While numerous techniques emphasize learning spatial and short-term temporal patterns, there has been limited…

Machine Learning · Computer Science 2025-03-18 Yi Ding , Chengxuan Tong , Shuailei Zhang , Muyun Jiang , Yong Li , Kevin Lim Jun Liang , Cuntai Guan

Accurate semantic segmentation of urban remote sensing images (URSIs) is essential for urban planning and environmental monitoring. However, it remains challenging due to the subtle texture differences and similar spatial structures among…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Guoyu Zhou , Jing Zhang , Yi Yan , Hui Zhang , Li Zhuo

Using a link between graph theory and the geometry hosting higher order topological matter, we fill part of the missing results in the engineering of domain walls supporting gapless states for systems with three vertical hinges. The…

Materials Science · Physics 2022-06-27 Lalla Btissam Drissi , El Hassan Saidi

Dissipatively stabilized cat qubits are promising for fault-tolerant quantum information processing, yet their non-Hermitian (NH) spectral topology remains largely unexplored. We uncover rich Liouvillian exceptional structures in a…

Quantum Physics · Physics 2026-04-23 Tian-Le Yang , Pei-Rong Han , Zhen-Biao Yang , Shi-Biao Zheng

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yan Wang , Xu Wei , Fengze Liu , Jieneng Chen , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille
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