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The Euler calculus -- an integral calculus based on Euler characteristic as a valuation on constructible functions -- is shown to be an incisive tool for answering questions about injectivity and invertibility of recent transforms based on…

Algebraic Topology · Mathematics 2018-06-15 Robert Ghrist , Rachel Levanger , Huy Mai

Topological methods are very rarely used in structural health monitoring (SHM), or indeed in structural dynamics generally, especially when considering the structure and topology of observed data. Topological methods can provide a way of…

Human-Computer Interaction · Computer Science 2022-09-14 Tristan Gowdridge , Nikolaos Dervilis , Keith Worden

In this article, we establish the mathematical foundations for modeling the randomness of shapes and conducting statistical inference on shapes using the smooth Euler characteristic transform. Based on these foundations, we propose two…

Methodology · Statistics 2024-05-27 Kun Meng , Jinyu Wang , Lorin Crawford , Ani Eloyan

Topological methods can provide a way of proposing new metrics and methods of scrutinising data, that otherwise may be overlooked. In this work, a method of quantifying the shape of data, via a topic called topological data analysis will be…

Machine Learning · Statistics 2022-09-25 Tristan Gowdridge , Nikolaos Dervilis , Keith Worden

The persistent homology transform (PHT) represents a shape with a multiset of persistence diagrams parameterized by the sphere of directions in the ambient space. In this work, we describe a finite set of diagrams that discretize the PHT…

Computational Geometry · Computer Science 2026-05-26 Brittany Terese Fasy , Samuel Micka , David L. Millman , Anna Schenfisch , Lucia Williams

Epigenetic Tracking (ET) is an Artificial Embryology system which allows for the evolution and development of large complex structures built from artificial cells. In terms of the number of cells, the complexity of the bodies generated with…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Alessandro Fontana , Borys Wróbel

This paper presents an experimental investigation on pattern formation and evolution in bilayered tubular organs using swelling deformation of polydimethylsiloxane (PDMS) and aims at supplying a thorough comparison with theoretical and…

Soft Condensed Matter · Physics 2022-02-15 Rui-Cheng Liu , Lishuai Jin , Zongxi Cai , Yang Liu

Thyroid nodule classification using ultrasound imaging is essential for early diagnosis and clinical decision-making; however, despite promising performance on in-distribution data, existing deep learning methods often exhibit limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yangmei Chen , Zhongyuan Zhang , Xikun Zhang , Xinyu Hao , Mingliang Hou , Renqiang Luo , Ziqi Xu

Deep learning-based medical image segmentation techniques have shown promising results when evaluated based on conventional metrics such as the Dice score or Intersection-over-Union. However, these fully automatic methods often fail to meet…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Liu Li , Qiang Ma , Cheng Ouyang , Johannes C. Paetzold , Daniel Rueckert , Bernhard Kainz

The weighted Euler characteristic transform (WECT) and Euler characteristic function (ECF) have proven to be useful tools in a variety of applications. However, current methods for computing these functions are either not optimized for GPU…

Computational Geometry · Computer Science 2026-04-06 Jessi Cisewski-Kehe , Brittany Terese Fasy , Alexander McCleary , Eli Quist

Topological Deep Learning seeks to enhance the predictive performance of neural network models by harnessing topological structures in input data. Topological neural networks operate on spaces such as cell complexes and hypergraphs, that…

Recent developments in shape reconstruction and comparison call for the use of many different (topological) descriptor types, such as persistence diagrams and Euler characteristic functions. We establish a framework to quantitatively…

Computational Geometry · Computer Science 2026-05-26 Brittany Terese Fasy , David L. Millman , Anna Schenfisch

Deep learning methods have demonstrated outstanding performances on classification and regression tasks on homogeneous data types (e.g., image, audio, and text data). However, tabular data still pose a challenge, with classic machine…

Machine Learning · Computer Science 2023-11-15 Antonio Briola , Yuanrong Wang , Silvia Bartolucci , Tomaso Aste

One of the essential tasks in connectomics is the morphology analysis of neurons and organelles like mitochondria to shed light on their biological properties. However, these biological objects often have tangled parts or complex branching…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Abhimanyu Talwar , Zudi Lin , Donglai Wei , Yuesong Wu , Bowen Zheng , Jinglin Zhao , Won-Dong Jang , Xueying Wang , Jeff W. Lichtman , Hanspeter Pfister

In this paper we introduce a statistic, the persistent homology transform (PHT), to model surfaces in $\mathbb{R}^3$ and shapes in $\mathbb{R}^2$. This statistic is a collection of persistence diagrams - multiscale topological summaries…

Statistics Theory · Mathematics 2014-07-16 Katharine Turner , Sayan Mukherjee , Doug M Boyer

Accurately modeling the spatiotemporal evolution of tumor morphology from baseline imaging is a pre-requisite for developing digital twin frameworks that can simulate disease progression and treatment response. Most existing approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Moinak Bhattacharya , Gagandeep Singh , Prateek Prasanna

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Electrical Impedance Tomography (EIT) is a powerful imaging technique with diverse applications, e.g., medical diagnosis, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Andreas Hauptmann , Bangti Jin , Peter Maass

We report upon the numerical computation of the Euler characteristic \chi (a topologic invariant) of the equipotential hypersurfaces \Sigma_v of the configuration space of the two-dimensional lattice $\phi^4$ model. The pattern…

Statistical Mechanics · Physics 2009-01-23 Roberto Franzosi , Marco Pettini , Lionel Spinelli

Neuronal morphology encodes critical information about circuit function, development, and disease, yet current methods analyze topology or graph structure in isolation. We introduce GraPHFormer, a multimodal architecture that unifies these…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Uzair Shah , Marco Agus , Mahmoud Gamal , Mahmood Alzubaidi , Corrado Cali , Pierre J. Magistretti , Abdesselam Bouzerdoum , Mowafa Househ